ENSMUSG00000009741


Mus musculus

Features
Gene ID: ENSMUSG00000009741
  
Biological name :Ubp1
  
Synonyms : Q811S7 / Ubp1 / upstream binding protein 1
  
Possible biological names infered from orthology : Q9NZI7
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F3
Gene start: 113930934
Gene end: 113977202
  
Corresponding Affymetrix probe sets: 10589848 (MoGene1.0st)   1455222_a_at (Mouse Genome 430 2.0 Array)   1460655_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112192
Ensembl peptide - ENSMUSP00000081946
Ensembl peptide - ENSMUSP00000149908
Ensembl peptide - ENSMUSP00000150023
Ensembl peptide - ENSMUSP00000009885
NCBI entrez gene - 22221     See in Manteia.
MGI - MGI:104889
RefSeq - XM_006512058
RefSeq - NM_001083319
RefSeq - NM_013699
RefSeq - XM_006512052
RefSeq - XM_006512054
RefSeq - XM_006512055
RefSeq - XM_006512050
RefSeq - XM_006512051
RefSeq Peptide - NP_038727
RefSeq Peptide - NP_001076788
swissprot - Q811S7
Ensembl - ENSMUSG00000009741
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ubp1ENSDARG00000018000Danio rerio
 UBP1ENSGALG00000035630Gallus gallus
 UBP1ENSG00000153560Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tfcp2 / Q9ERA0 / Mus musculus transcription factor CP2 (Tfcp2), transcript variant 3, mRNA. / Q12800* / transcription factor CP2*ENSMUSG0000000973367
Q3UNW5 / Tfcp2l1 / Transcription factor CP2-like protein 1 / Q9NZI6* / transcription factor CP2 like 1*ENSMUSG0000002638058
Grhl2 / Q8K5C0 / Grainyhead-like / Q6ISB3* / grainyhead like transcription factor 2*ENSMUSG0000002228623
Grhl1 / Q921D9 / Grainyhead-like / Q9NZI5* / grainyhead like transcription factor 1*ENSMUSG0000002065621
Grhl3 / Q5FWH3 / Grainyhead-like / Q8TE85* / grainyhead like transcription factor 3*ENSMUSG0000003718821


Protein motifs (from Interpro)
Interpro ID Name
 IPR007604  CP2 transcription factor
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000260 abnormal angiogenesis "aberrant process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000292 distended pericardial sacs "stretched outer parietal layer of the pericardium" [J:25248]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0000295 poorly developed ventricular trabeculae "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001718 abnormal yolk sac "malformed extraembryonic tissue which contributes to hematopoietic circulation" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:12623]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001719 absent vitelline blood vessels "missing vasculature of the yolk sac" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62571, J:12623]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001723 disorganized vascular plexus 
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002652 thin myocardial wall "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0004937 dilated heart "stretched or widened aperture of the luminal spaces of the heart, usually with an increase in contained fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Disp1icb/Disp1tm1Amc,Shhtm1Amc/Shh+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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