ENSMUSG00000014503


Mus musculus

Features
Gene ID: ENSMUSG00000014503
  
Biological name :Pkd2l2
  
Synonyms : Pkd2l2 / Polycystic kidney disease 2-like 2 protein / Q9JLG4
  
Possible biological names infered from orthology : polycystin 2 like 2, transient receptor potential cation channel / Q9NZM6
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: B1
Gene start: 34409423
Gene end: 34442789
  
Corresponding Affymetrix probe sets: 10454683 (MoGene1.0st)   1419422_at (Mouse Genome 430 2.0 Array)   1449469_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000014647
Ensembl peptide - ENSMUSP00000127257
NCBI entrez gene - 53871     See in Manteia.
MGI - MGI:1858231
RefSeq - XM_017317951
RefSeq - NM_001163004
RefSeq - NM_016927
RefSeq - XM_017317948
RefSeq - XM_017317949
RefSeq - XM_017317950
RefSeq - XM_006526097
RefSeq - XM_006526101
RefSeq - XM_017317944
RefSeq - XM_017317945
RefSeq - XM_017317946
RefSeq - XM_017317947
RefSeq Peptide - NP_058623
RefSeq Peptide - NP_001156476
swissprot - Q9JLG4
Ensembl - ENSMUSG00000014503
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PKD2L2ENSGALG00000006120Gallus gallus
 PKD2L2ENSG00000078795Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2A259 / Pkd2l1 / Polycystic kidney disease 2-like 1 protein / Q9P0L9* / polycystin 2 like 1, transient receptor potential cation channel*ENSMUSG0000003757846
Pkd2 / O35245 / Polycystin-2 / Q13563* / polycystin 2, transient receptor potential cation channel*ENSMUSG0000003446244
Pkd1l2ENSMUSG0000003441623
Pkd1l3 / Q2EG98 / Polycystic kidney disease protein 1-like 3 / Q7Z443* / polycystin 1 like 3, transient receptor potential channel interacting*ENSMUSG0000004882718
Pkdrej / polycystin family receptor for egg jelly / Q9NTG1*ENSMUSG0000005249617
Pkd1 / O08852 / Polycystin-1 / P98161* / polycystin 1, transient receptor potential channel interacting*ENSMUSG0000003285517
Pkd1l1 / polycystin 1 like 1, transient receptor potential channel interacting / Q8TDX9*ENSMUSG0000004663417


Protein motifs (from Interpro)
Interpro ID Name
 IPR003915  Polycystic kidney disease type 2 protein
 IPR013122  Polycystin cation channel, PKD1/PKD2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0050982 detection of mechanical stimulus IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005262 calcium channel activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Seletm2Alb/Seletm2Alb,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pdgfrbtm1b(EUCOMM)Hmgu/Pdgfrb+
Genetic Background: C57BL/6N-Pdgfrbtm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr