ENSMUSG00000020358


Mus musculus

Features
Gene ID: ENSMUSG00000020358
  
Biological name :Hnrnpab
  
Synonyms : Heteroous nuclear ribonucleoprotein A/B / Hnrnpab / Q99020
  
Possible biological names infered from orthology : heterogeneous nuclear ribonucleoprotein A/B / Q99729
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B1.3
Gene start: 51600100
Gene end: 51606847
  
Corresponding Affymetrix probe sets: 10385686 (MoGene1.0st)   1415914_at (Mouse Genome 430 2.0 Array)   1426114_at (Mouse Genome 430 2.0 Array)   1431349_at (Mouse Genome 430 2.0 Array)   1448144_at (Mouse Genome 430 2.0 Array)   1453849_s_at (Mouse Genome 430 2.0 Array)   1455855_x_at (Mouse Genome 430 2.0 Array)   1459880_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074238
Ensembl peptide - ENSMUSP00000098807
Ensembl peptide - ENSMUSP00000104731
NCBI entrez gene - 15384     See in Manteia.
MGI - MGI:1330294
RefSeq - NM_010448
RefSeq - NM_001048061
RefSeq Peptide - NP_001041526
RefSeq Peptide - NP_034578
swissprot - Q20BD0
swissprot - Q544Z3
swissprot - Q80XR6
swissprot - Q99020
Ensembl - ENSMUSG00000020358
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hnrnpabaENSDARG00000007960Danio rerio
 hnrnpabbENSDARG00000099865Danio rerio
 HNRNPABENSGALG00000014381Gallus gallus
 Q99729ENSG00000197451Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hnrnpd / Q60668 / Heteroous nuclear ribonucleoprotein D0 / Q14103* / heterogeneous nuclear ribonucleoprotein D*ENSMUSG0000000056865
Hnrnpdl / heterogeneous nuclear ribonucleoprotein D like / O14979*ENSMUSG0000002932856
Rbm31y / predicted, 21379 ENSMUSG0000009536538
Msi2 / Q920Q6 / RNA-binding 2 / Q96DH6* / musashi RNA binding protein 2*ENSMUSG0000006976935
Msi1 / Q61474 / RNA-binding 1 / O43347* / musashi RNA binding protein 1*ENSMUSG0000005425633
Dazap1 / Q9JII5 / DAZ-associated protein 1 / Q96EP5*ENSMUSG0000006956529
Q921F2 / Tardbp / TAR DNA binding protein / Q13148*ENSMUSG0000004145927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR012956  CARG-binding factor, N-terminal
 IPR034846  hnRNPAB, RNA recognition motif 1
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IGI
 biological_processGO:0001837 epithelial to mesenchymal transition IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008235 increased susceptibility to neuronal excitotoxicity "greater than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kaniate-induced neuronal cell death mediated via a glutamate excitotoxic process" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: E2f1tm1Njd/E2f1tm1Njd,Klhl40tm1.1Itl/Klhl40tm1.1Itl
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6N

 MP:0008415 abnormal neurite morphology "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572]
Show

Allelic Composition: E2f1tm1Njd/E2f1tm1Njd,Klhl40tm1.1Itl/Klhl40tm1.1Itl
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6N

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: E2f1tm1Njd/E2f1tm1Njd,Klhl40tm1.1Itl/Klhl40tm1.1Itl
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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