ENSMUSG00000020911


Mus musculus

Features
Gene ID: ENSMUSG00000020911
  
Biological name :Krt19
  
Synonyms : Keratin, type I cytoskeletal 19 / Krt19 / P19001
  
Possible biological names infered from orthology : keratin 19 / P08727
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 100140810
Gene end: 100148665
  
Corresponding Affymetrix probe sets: 10391036 (MoGene1.0st)   1417156_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000007317
NCBI entrez gene - 16669     See in Manteia.
MGI - MGI:96693
RefSeq - NM_001313963
RefSeq - NM_008471
RefSeq Peptide - NP_001300892
RefSeq Peptide - NP_032497
swissprot - P19001
swissprot - B1AQ78
Ensembl - ENSMUSG00000020911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyt1ENSDARG00000092947Danio rerio
 cyt1lENSDARG00000036832Danio rerio
 krt1-19dENSDARG00000023082Danio rerio
 krt15ENSDARG00000036840Danio rerio
 krt17ENSDARG00000094041Danio rerio
 krt91ENSDARG00000036830Danio rerio
 krt92ENSDARG00000036834Danio rerio
 krt93ENSDARG00000044976Danio rerio
 krt94ENSDARG00000044975Danio rerio
 krt95ENSDARG00000014356Danio rerio
 krt96ENSDARG00000095147Danio rerio
 krt97ENSDARG00000000212Danio rerio
 krtt1c19eENSDARG00000090268Danio rerio
 si:ch211-156l18.7ENSDARG00000022334Danio rerio
 KRT19ENSGALG00000019719Gallus gallus
 KRT19ENSG00000171345Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Krt42 / Q6IFX2 / Keratin, type I cytoskeletal 42 ENSMUSG0000005365466
Krt13 / P08730 / Keratin, type I cytoskeletal 13 / P13646* / keratin 13*ENSMUSG0000004404165
Krt14 / Q61781 / Keratin, type I cytoskeletal 14 ENSMUSG0000004554565
Krt15 / keratin 15 / P19012*ENSMUSG0000005414665
Krt17 / Q9QWL7 / Keratin, type I cytoskeletal 17 / Q04695* / keratin 17*ENSMUSG0000003555765
Krt16 / Q9Z2K1 / keratin 16 / P08779*ENSMUSG0000005379762
Krt10 / keratin 10 / P13645*ENSMUSG0000001976157
Krt12 / keratin 12 / Q99456*ENSMUSG0000002091252
Krt24 / A1L317 / Keratin, type I cytoskeletal 24 / Q2M2I5* / keratin 24*ENSMUSG0000002091351
Krt27 / Q9Z320 / Keratin, type I cytoskeletal 27 / Q7Z3Y8* / keratin 27*ENSMUSG0000001758849
Krt28 / A6BLY7 / Keratin, type I cytoskeletal 28 / Q7Z3Y7* / keratin 28*ENSMUSG0000005593749
Krt25 / Q8VCW2 / Keratin, type I cytoskeletal 25 / Q7Z3Z0* / keratin 25*ENSMUSG0000003583148


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR002957  Keratin, type I
 IPR018039  Intermediate filament protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IDA
 biological_processGO:0043627 response to estrogen IEA
 biological_processGO:0045214 sarcomere organization IEA
 biological_processGO:0060706 cell differentiation involved in embryonic placenta development IGI
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016010 dystrophin-associated glycoprotein complex IEA
 cellular_componentGO:0016327 apicolateral plasma membrane IDA
 cellular_componentGO:0030018 Z disc IDA
 cellular_componentGO:0042383 sarcolemma IDA
 cellular_componentGO:0043034 costamere ISO
 cellular_componentGO:0071944 cell periphery IEA
 cellular_componentGO:1990357 terminal web IDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008307 structural constituent of muscle IEA


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000164 abnormal cartilage development "anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Cd19tm1(cre)Cgn/Cd19+,Cxcr4tm1Tng/Cxcr4tm2Tng
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000351 increased cell proliferation "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj
Genetic Background: Not Specified

 MP:0000652 enlarged sebaceous gland "increased size of the sebum secreting glands of the hair shaft" [J:30249]
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Allelic Composition: Tbx4tm1(cre)Tmj/Tbx4tm1(cre)Tmj
Genetic Background: Not Specified

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Flt4tm1Ali/Flt4tm2Ali
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR

 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
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Allelic Composition: Gabrg2tm2.1Geh/Gabrg2tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0001711 abnormal placenta 
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0001716 abnormal placental labyrinth "malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [J:23171]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0001726 abnormal allantois "malformed fetal membrane which contributes to the formation of the umbilical cord and placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:12622]
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Allelic Composition: Pink1tm1Aub/Pink1tm1Aub
Genetic Background: involves: 129S/SvEv

 MP:0002038 carcinoma "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0002051 skin papilloma "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/?
Genetic Background: involves: 129X1/SvJ

 MP:0002086 abnormal extraembryonic tissue morphology "structural abnormality or development of the membranes involved with embryonic protection and nutrition" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:40594, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gabrg2tm2.1Geh/Gabrg2tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cacna1smdg/Cacna1smdg
Genetic Background: involves: 129P1/ReJ * STOCK T/t4

Allelic Composition: Krt19tm1(cre/ERT)Ggu/Krt19tm1(cre/ERT)Ggu
Genetic Background: involves: C57BL/6 * CD-1

 MP:0002404 intestinal adenoma "benign tumors of the small and large intestine" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/?
Genetic Background: involves: 129X1/SvJ

 MP:0002740 heart hypoplasia "decreased cell number in the heart" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:77765]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002785 absent Leydig cells "lack of the interstitial cells of the seminiferous tubules that secrete testosterone " [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002995 primary sex reversal "gonad type is not consistent with chromosomal sex" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003645 increased number of pancreatic beta cells "greater than normal number of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Nrxn2tm4Sud/Nrxn2tm4Sud
Genetic Background: involves: C57BL/6

 MP:0003780 lip tumor "presence of abnormal rapidly proliferating cells in the lip, usually in the form of a distinct mass" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0003830 abnormal testis development "abnormal morphogenesis of the male reproductive gland containing the germ cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:100020]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

 MP:0004255 abnormal spongiotrophoblast layer morphology "anomaly in the structure of the outer structural layer of the rodent placenta" [PMID:11433360]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0004259 small placenta "reduced size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gabrg2tm2.1Geh/Gabrg2tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0005031 abnormal trophoblast "malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0005033 abnormal trophoblast cells "anomaly of the cells covering the blastocyst that erode the uterine mucosa and contribute to the formation of the placenta " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator, J:57761]
Show

Allelic Composition: Gabrg2tm2.1Geh/Gabrg2tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0006372 impaired placental function "reduction in the ability of the placenta to supply nutrients or remove waste" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0006424 absent testis cords "missing the attachments derived from the primordial seminiferous cords that differentiate into seminiferous tubules in adolescence" [J:104330, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008803 abnormal placental labyrinth vasculature morphology "any structural anomaly in blood vessels of the layer of the placenta where embryonic and maternal blood vessels interdigitate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0008959 abnormal spongiotrophoblast cell morphology "any structural anomaly of a trophoblast cell that arises in the junctional zone of the placenta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0009139 failure of Mullerian duct regression "failure of the transient embryonic paramesonephric ducts, which normally develop into the oviduct, uterus, cervix and upper vagina in the female, to regress in the male; persistence of Mullerian ducts is typically consistent with a loss of anti-Mullerian hormone signaling and may allow development of the female reproductive tract in males" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009238 coiled sperm flagellum "abnormal twisting of the sperm flagellum into coils or spirals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009239 short sperm flagellum "decreased length of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009241 thick sperm flagellum "increased thickness of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009377 ectopic manchette "abnormal position of the conic array of microtubules that normally invests the posterior nucleus of a spermatid" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Wwtr1tm1Benj/Wwtr1tm1Benj
Genetic Background: 129S6/SvEvTac-Wwtr1tm1Benj

Allelic Composition: Krt19tm1Alki/Krt19+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0009397 increased trophoblast giant cell number "greater than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0009535 abnormal skin sebaceous gland morphology "any structural anomaly of the holocrine glands of the dermis that secrete sebum into the hair follicles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0009759 abnormal hair follicle bulge "an anomaly in the area located in the bottom of the permanent portion of a resting (telogen) hair follicle where the cells of the external root sheath of the hair follicle are contiguous with the basal layer of the epidermis; this portion of the follicle is involved in the generation of a new hair at the onset of the hair growth cycle (anagen)" [ISBN:0-8493-8372-2 "Sundberg, JP (ed.) Handbook of Mouse Mutations with Skin and Hair Abnormalities", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0009794 sebaceous gland hyperplasia "overdevelopment and increased size of the sebum secreting glands of the hair shaft, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

 MP:0010279 increased gastrointestinal tumor incidence "greater than the expected number of tumors originating in the gastrointestinal system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

 MP:0010300 increased skin tumor incidence "greater than the expected number of neoplasms in the skin tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Krastm4Tyj/Kras+,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac

Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Gabrg2tm2.1Geh/Gabrg2tm2.1Geh
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N

Allelic Composition: Flt4tm1Ali/Flt4tm2.1Ali,Krt19tm1(cre)Mmt/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL

Allelic Composition: Krt19tm2Mmt/Krt19tm2Mmt,Krt8tm1Rgo/Krt8tm1Rgo
Genetic Background: FVB.129S2-Krt19tm2Mmt Krt8tm1Rgo

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Pink1tm1Aub/Pink1tm1Aub
Genetic Background: involves: 129S/SvEv

 MP:0011400 complete lethality "all individuals of a given genotype in a population die before the end of the normal lifespan but time(s) of death are unspecified" [MGI:llw2]
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Allelic Composition: Krastm4Tyj/Kras+,Trp53tm1Brn/Trp53tm1Brn,Krt19tm1(cre/ERT)Ggu/Krt19+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

 MP:0012756 impaired cranial neural crest cell differentiation "abnormal or arrest of differentiation or patterning of the cranial neural crest cells" [MGI:anna]
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Allelic Composition: Sox9tm1Gsr/Sox9tm1Gsr,Krt19tm1(cre)Mmt/Krt19+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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