ENSMUSG00000020912


Mus musculus

Features
Gene ID: ENSMUSG00000020912
  
Biological name :Krt12
  
Synonyms : keratin 12 / Krt12
  
Possible biological names infered from orthology : Q99456
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 99415666
Gene end: 99422259
  
Corresponding Affymetrix probe sets: 10390841 (MoGene1.0st)   1419230_at (Mouse Genome 430 2.0 Array)   1419231_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000017741
NCBI entrez gene - 268482     See in Manteia.
MGI - MGI:96687
RefSeq - NM_010661
RefSeq - XM_006533413
RefSeq Peptide - NP_034791
swissprot - Z4YJD9
Ensembl - ENSMUSG00000020912
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyt1ENSDARG00000092947Danio rerio
 cyt1lENSDARG00000036832Danio rerio
 krt1-19dENSDARG00000023082Danio rerio
 krt15ENSDARG00000036840Danio rerio
 krt17ENSDARG00000094041Danio rerio
 krt91ENSDARG00000036830Danio rerio
 krt92ENSDARG00000036834Danio rerio
 krt93ENSDARG00000044976Danio rerio
 krt94ENSDARG00000044975Danio rerio
 krt95ENSDARG00000014356Danio rerio
 krt96ENSDARG00000095147Danio rerio
 krt97ENSDARG00000000212Danio rerio
 krtt1c19eENSDARG00000090268Danio rerio
 si:ch211-156l18.7ENSDARG00000022334Danio rerio
 KRT12ENSGALG00000019715Gallus gallus
 KRT12ENSG00000187242Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Krt24 / A1L317 / Keratin, type I cytoskeletal 24 / Q2M2I5* / keratin 24*ENSMUSG0000002091355
Krt10 / keratin 10 / P13645*ENSMUSG0000001976153
Krt14 / Q61781 / Keratin, type I cytoskeletal 14 ENSMUSG0000004554551
Krt16 / Q9Z2K1 / keratin 16 / P08779*ENSMUSG0000005379750
Krt42 / Q6IFX2 / Keratin, type I cytoskeletal 42 ENSMUSG0000005365449
Krt27 / Q9Z320 / Keratin, type I cytoskeletal 27 / Q7Z3Y8* / keratin 27*ENSMUSG0000001758849
Krt28 / A6BLY7 / Keratin, type I cytoskeletal 28 / Q7Z3Y7* / keratin 28*ENSMUSG0000005593749
Krt13 / P08730 / Keratin, type I cytoskeletal 13 / P13646* / keratin 13*ENSMUSG0000004404148
Krt17 / Q9QWL7 / Keratin, type I cytoskeletal 17 / Q04695* / keratin 17*ENSMUSG0000003555748
Krt15 / keratin 15 / P19012*ENSMUSG0000005414648
Krt25 / Q8VCW2 / Keratin, type I cytoskeletal 25 / Q7Z3Z0* / keratin 25*ENSMUSG0000003583147
Krt19 / P19001 / Keratin, type I cytoskeletal 19 / P08727* / keratin 19*ENSMUSG0000002091143


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR002957  Keratin, type I
 IPR018039  Intermediate filament protein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005882 intermediate filament IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Krt12tm1.1(KRT12*L132P)Arte/Krt12+
Genetic Background: involves: C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ins2C95S/Ins2+
Genetic Background: C3HeB/FeJ-Ins2C95S

 MP:0006000 abnormal corneal epithelium "malformation in the one or more of the layers of epithelial cells covering the front of the cornea" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Gja5tm1(Gja7)Hvr/Gja5tm1(Gja7)Hvr
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Krt12tm1.1(KRT12*L132P)Arte/Krt12+
Genetic Background: involves: C57BL/6

Allelic Composition: Krt12tm1.1(KRT12*L132P)Arte/Krt12tm1.1(KRT12*L132P)Arte
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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