ENSMUSG00000020955


Mus musculus

Features
Gene ID: ENSMUSG00000020955
  
Biological name :Ap4s1
  
Synonyms : AP-4 complex subunit sigma-1 / Ap4s1 / Q9WVL1
  
Possible biological names infered from orthology : adaptor related protein complex 4 sigma 1 subunit / Q9Y587
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: B3
Gene start: 51691033
Gene end: 51744786
  
Corresponding Affymetrix probe sets: 10395672 (MoGene1.0st)   1451665_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021338
Ensembl peptide - ENSMUSP00000151472
NCBI entrez gene - 11782     See in Manteia.
MGI - MGI:1337065
RefSeq - XM_017314942
RefSeq - NM_021710
RefSeq - XM_006515437
RefSeq - XM_017314940
RefSeq - XM_017314941
RefSeq - XM_006515432
RefSeq - XM_006515433
RefSeq - XM_006515434
RefSeq - XM_006515436
RefSeq Peptide - NP_068356
swissprot - Q9WVL1
swissprot - A0A1W2P708
Ensembl - ENSMUSG00000020955
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ap4s1ENSDARG00000054220Danio rerio
 AP4S1ENSGALG00000009936Gallus gallus
 AP4S1ENSG00000100478Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ap2s1 / P62743 / AP-2 complex subunit sigma / P53680* / adaptor related protein complex 2 sigma 1 subunit*ENSMUSG0000000803642
Ap1s2 / Q9DB50 / AP-1 complex subunit sigma-2 / P56377* / adaptor related protein complex 1 sigma 2 subunit*ENSMUSG0000003136736
Ap1s3 / Q7TN05 / AP-1 complex subunit sigma-3 / Q96PC3* / adaptor related protein complex 1 sigma 3 subunit*ENSMUSG0000005470236
Ap1s1 / P61967 / AP-1 complex subunit sigma-1A / P61966* / adaptor related protein complex 1 sigma 1 subunit*ENSMUSG0000000484935


Protein motifs (from Interpro)
Interpro ID Name
 IPR011012  Longin-like domain superfamily
 IPR016635  Adaptor protein complex, sigma subunit
 IPR022775  AP complex, mu/sigma subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030124 AP-4 adaptor complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001998 Ap4e1 / Q80V94 / AP-4 complex subunit epsilon-1 / Q9UPM8* / adaptor related protein complex 4 epsilon 1 subunit*  / complex
 ENSMUSG00000022892 App / P12023 / amyloid beta (A4) precursor protein / P05067* / amyloid beta precursor protein*  / reaction / complex
 ENSMUSG00000019518 Ap4m1 / Q9JKC7 / AP-4 complex subunit mu-1 / O00189* / adaptor related protein complex 4 mu 1 subunit*  / complex
 ENSMUSG00000032952 Ap4b1 / Q9WV76 / AP-4 complex subunit beta-1 / Q9Y6B7* / adaptor related protein complex 4 beta 1 subunit*  / complex






 

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