ENSMUSG00000021071


Mus musculus

Features
Gene ID: ENSMUSG00000021071
  
Biological name :Trim9
  
Synonyms : E3 ubiquitin-protein ligase TRIM9 / Q8C7M3 / Trim9
  
Possible biological names infered from orthology : Q9C026 / tripartite motif containing 9
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C2
Gene start: 70244533
Gene end: 70347614
  
Corresponding Affymetrix probe sets: 10400866 (MoGene1.0st)   1434249_s_at (Mouse Genome 430 2.0 Array)   1434595_at (Mouse Genome 430 2.0 Array)   1443989_at (Mouse Genome 430 2.0 Array)   1454886_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152496
Ensembl peptide - ENSMUSP00000152147
Ensembl peptide - ENSMUSP00000152691
Ensembl peptide - ENSMUSP00000152887
Ensembl peptide - ENSMUSP00000152692
Ensembl peptide - ENSMUSP00000106149
Ensembl peptide - ENSMUSP00000106151
Ensembl peptide - ENSMUSP00000127081
NCBI entrez gene - 94090     See in Manteia.
MGI - MGI:2137354
RefSeq - XM_017315265
RefSeq - NM_053167
RefSeq - XM_006516400
RefSeq - XM_006516401
RefSeq - XM_006516402
RefSeq - XM_006516403
RefSeq - XM_006516404
RefSeq - XM_006516405
RefSeq - XM_006516406
RefSeq - XM_006516407
RefSeq - XM_017315263
RefSeq - XM_017315264
RefSeq - NM_001110202
RefSeq - NM_001110203
RefSeq - NM_001286386
RefSeq - NM_001286387
RefSeq - NM_001286388
RefSeq Peptide - NP_001103673
RefSeq Peptide - NP_001273315
RefSeq Peptide - NP_001273316
RefSeq Peptide - NP_001273317
RefSeq Peptide - NP_444397
RefSeq Peptide - NP_001103672
swissprot - E9Q524
swissprot - A0A1Y7VP88
swissprot - E9QLH4
swissprot - Q8C7M3
swissprot - A0A1Y7VJX8
Ensembl - ENSMUSG00000021071
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trim9ENSDARG00000039123Danio rerio
 TRIM9ENSGALG00000012367Gallus gallus
 TRIM9ENSG00000100505Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q505D9 / Trim67 / Tripartite motif-containing protein 67 / Q6ZTA4* / tripartite motif containing 67*ENSMUSG0000003691360
Mid1 / O70583 / E3 ubiquitin-protein ligase Midline-1 / O15344* / midline 1*ENSMUSG0000003529922
Mid2 / Mus musculus midline 2 (Mid2), transcript variant 2, mRNA. / Q9UJV3* / midline 2*ENSMUSG0000000026622
Q7TNM2 / Trim46 / tripartite motif-containing 46 / Q7Z4K8*ENSMUSG0000004276621
Q80WG7 / Trim36 / E3 ubiquitin-protein ligase Trim36 / Q9NQ86* / tripartite motif containing 36*ENSMUSG0000003394920
Fsd1 / Q7TPM6 / Fibronectin type III and SPRY domain-containing protein 1 / Q9BTV5* / fibronectin type III and SPRY domain containing 1*ENSMUSG0000001158913
Fsd1l / Q8BYN5 / Mus musculus fibronectin type III and SPRY domain containing 1-like (Fsd1l), transcript variant 3, mRNA. / Q9BXM9* / fibronectin type III and SPRY domain containing 1 like*ENSMUSG0000005475213
Trim63 / tripartite motif-containing 63 / Q969Q1*ENSMUSG0000002883412
Trim55 / tripartite motif-containing 55 / Q9BYV6*ENSMUSG0000006091312
Q9ERP3 / Trim54 / Tripartite motif-containing protein 54 / Q9BYV2* / tripartite motif containing 54*ENSMUSG0000006207711


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003649  B-box, C-terminal
 IPR003877  SPRY domain
 IPR003961  Fibronectin type III
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR017903  COS domain
 IPR017907  Zinc finger, RING-type, conserved site
 IPR035029  E3 ubiquitin-protein ligase TRIM9
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016079 synaptic vesicle exocytosis ISO
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035544 negative regulation of SNARE complex assembly IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0045955 negative regulation of calcium ion-dependent exocytosis IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000780 abnormal corpus callosum morphology "malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa
Genetic Background: involves: 129P2/OlaHsd

 MP:0004811 abnormal neuron physiology "anomalous function of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:National Library of Medicine_Medical Subject Headings]
Show

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa
Genetic Background: involves: 129P2/OlaHsd

 MP:0009937 abnormal neuron differentiation "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Tg(Thy1-EGFP)MJrs/0,Trim9tm1.1Slgu/Trim9tm1.1Slgu
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J * CBA

 MP:0012443 increased corpus callosum size "larger thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [ISBN:0-683-40008-8, MGI:csmith]
Show

Allelic Composition: Nf2tm2Gth/Nf2tm2Gth,Yap1tm2.1Dupa/Yap1tm2.1Dupa
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Tg(Thy1-EGFP)MJrs/0,Trim9tm1.1Slgu/Trim9tm1.1Slgu
Genetic Background: involves: 129S4/SvJae * BALB/cJ * C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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