Manteia

ENSMUSG00000023387

Mus musculus

Features

Gene ID:	ENSMUSG00000023387

Biological name :	Kcnk16

Synonyms :	Kcnk16

Possible biological names infered from orthology :	potassium two pore domain channel subfamily K member 16 / Q96T55

Species:	Mus musculus

Chr. number:	14
Strand:	-1
Band:	A3
Gene start:	20261376
Gene end:	20269199

Corresponding Affymetrix probe sets:	10417807 (MoGene1.0st) 1429913_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000024155 Ensembl peptide - ENSMUSP00000153256 NCBI entrez gene - 74571 See in Manteia. MGI - MGI:1921821 RefSeq - NM_029006 RefSeq Peptide - NP_083282 swissprot - G5E845 swissprot - A0A286YDH8 Ensembl - ENSMUSG00000023387

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Kcnk10 / potassium channel, subfamily K, member 10 / P57789* / potassium two pore domain channel subfamily K member 10*	ENSMUSG00000033854	37
Kcnk4 / O88454 / Potassium channel subfamily K member 4 / Q9NYG8* / potassium two pore domain channel subfamily K member 4*	ENSMUSG00000024957	36
Kcnk2 / P97438 / Mus musculus potassium channel, subfamily K, member 2 (Kcnk2), transcript variant 5, mRNA. / O95069* / potassium two pore domain channel subfamily K member 2*	ENSMUSG00000037624	35
Kcnk5 / potassium two pore domain channel subfamily K member 5 / O95279*	ENSMUSG00000023243	35
Kcnk1 / O08581 / Potassium channel subfamily K member 1 / O00180* / potassium two pore domain channel subfamily K member 1*	ENSMUSG00000033998	30
Kcnk6 / potassium inwardly-rectifying channel, subfamily K, member 6 / Q9Y257* / potassium two pore domain channel subfamily K member 6*	ENSMUSG00000046410	30
Kcnk15 / potassium two pore domain channel subfamily K member 15 / Q9H427*	ENSMUSG00000035238	30
Kcnk3 / O35111 / Potassium channel subfamily K member 3 / O14649* / potassium two pore domain channel subfamily K member 3*	ENSMUSG00000049265	30
Kcnk9 / Q3LS21 / Potassium channel subfamily K member 9 / Q9NPC2* / potassium two pore domain channel subfamily K member 9*	ENSMUSG00000036760	29
Kcnk7 / potassium two pore domain channel subfamily K member 7 / Q9Y2U2*	ENSMUSG00000024936	26

Protein motifs (from Interpro)

Interpro ID	Name
IPR003092	Two pore domain potassium channel, TASK family
IPR003280	Two pore domain potassium channel
IPR013099	Potassium channel domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0006813	potassium ion transport	ISO
biological_process	GO:0030322	stabilization of membrane potential	IBA
biological_process	GO:0071805	potassium ion transmembrane transport	IBA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0005267	potassium channel activity	ISO
molecular_function	GO:0022841	potassium ion leak channel activity	IBA

Pathways (from Reactome)

Pathway description

Phase 4 - resting membrane potential

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0003058	increased insulin secretion	"greater than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission]	Show Allelic Composition: Ano6^tm1Avor/Ano6^tm1Avor Genetic Background: involves: 129
MP:0003562	abnormal beta cell physiology	"anomaly in the function of the insulin-producing cells of the islets of Langerhans in the pancreas" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ano6^tm1Avor/Ano6^tm1Avor Genetic Background: involves: 129
MP:0013277	abnormal fasted circulating glucose level	"any anomaly in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]	Show Allelic Composition: Ano6^tm1Avor/Ano6^tm1Avor Genetic Background: involves: 129

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSMUSG00000023387	Kcnk16 / Q96T55* / potassium two pore domain channel subfamily K member 16*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr