MP:0000074 | abnormal neurocranium morphology | "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000079 | abnormal basioccipital bone morphology | "malformed basilar process of the occipital bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000097 | short maxilla | "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000106 | abnormal basisphenoid bone morphology | "malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000107 | abnormal frontal bone morphology | "malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000120 | malocclusion | "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000160 | kyphosis | "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Ltbp3m1Btlr/Ltbp3m1Btlr Genetic Background: either: C57BL/6J-Ltbp3m1Btlr or (involves: C3H/HeJ * C57BL/6J)
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MP:0000428 | abnormal craniofacial morphology | "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mapkapk5tm1Pqs/Mapkapk5+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0000438 | abnormal skull morphology | "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000440 | domed skull | |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0000755 | hindlimb paralysis | "loss of power of voluntary movement in the muscles of the hindlimb through injury or disease of it or its nerve supply" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ltbp3m1Btlr/Ltbp3m1Btlr Genetic Background: either: C57BL/6J-Ltbp3m1Btlr or (involves: C3H/HeJ * C57BL/6J)
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0001300 | ocular hypertelorism | "increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0001349 | excessive tearing | "an unusually high amount of fluid secreted by the lacrimal glands, often resulting in overflow of fluid from the eye" [hdene:Howard Dene, Mouse Genome Informatics Curator, J:38104] |
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Allelic Composition: Ltbp3m1Btlr/Ltbp3m1Btlr Genetic Background: either: C57BL/6J-Ltbp3m1Btlr or (involves: C3H/HeJ * C57BL/6J)
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Ltbp3m1Btlr/Ltbp3m1Btlr Genetic Background: either: C57BL/6J-Ltbp3m1Btlr or (involves: C3H/HeJ * C57BL/6J)
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MP:0002092 | abnormal eye morphology | "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0002116 | abnormal craniofacial bone morphology | "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002233 | abnormal nose morphology | "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0002576 | abnormal enamel morphology | "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002577 | reduced enamel thickness | "thin hard coating of the exposed portion of the tooth" [J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002932 | abnormal joint | "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002998 | abnormal bone remodeling | "aberrant process of the turnover of bone matrix that involves a balance of resorbtion and formation by osteoclasts and osteoblasts, respectively" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003047 | abnormal thoracic vertebrae morphology | "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003048 | abnormal cervical vertebrae morphology | "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003408 | increased width of hypertrophic chondrocyte zone | "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003416 | premature bone ossification | "early onset of the formation of bone" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003560 | osteoarthritis | "a type of arthritis that is caused by the breakdown and eventual loss of the cartilage of one or more joints" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95374] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0003662 | abnormal proliferative zone | "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0004053 | abnormal synchondrosis | "anomalous or persistent cartilagenous fusion of two bones " [J:102870, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Ltbp3m1Btlr/Ltbp3m1Btlr Genetic Background: either: C57BL/6J-Ltbp3m1Btlr or (involves: C3H/HeJ * C57BL/6J)
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MP:0004686 | decreased length of long bones | "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0005422 | osteosclerosis | "abnormal hardening or eburnation (change in exposed subchondral bone in degenerative joint disease in which bone is converted into a dense substance with a smooth surface) of bone " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathy M Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010029 | abnormal basicranium morphology | "any structural anomaly of the sloping floor of the cranial cavity that is comprised of parts of the ethmoidal, occipital and sphenoid bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010099 | abnormal thoracic cage shape | "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010208 | prognathia | "abnormal protrusion of the mandible relative to the facial skeleton and soft tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010714 | coloboma of the iris | "congenital defect of the iris in which some part of the structure is absent" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0010747 | abnormal enamel organ morphology | "any structural anomaly of the circumscribed mass of ectodermal cells which bud off from the dental lamina; it becomes cup-shaped and develops on its internal face the ameloblast layer of cells that produces the enamel cap of a developing tooth" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010872 | increased trabecular bone mass | "greater total amount of trabecular bone tissue contained in the skeleton" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0010941 | abnormal foramen magnum morphology | "any structural anomaly of the large orifice in the occipital bone through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0014166 | ectopic cranial bone | "the appearance of an extra bone structure at an atypical location in or near the cranium" [MGI:csmith] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0030066 | short face | "an abnormally decreased height (length) of the face" [MGI:anna] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0030104 | round orbits | "orbits present a more circular rather than the ususal oval appearance" [MGI:anna, PMID:27671791] |
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Allelic Composition: Apobtm2Sgy/Apobtm2Sgy,Apoetm1Unc/Apoetm1Unc,Lepob/Lepob Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
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MP:0030245 | round head | "overall shape of the head is more circular than usual as viewed from the front" [MGI:anna] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0030264 | occipital bossing | "an area of marked prominence or protrusion in the occipital region at the back of the skull" [MGI:anna] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0030420 | short basicranium | "decreased length of the anterior and/or posterior portions of the skull base" [MGI:anna] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0030541 | misaligned incisors | "abnormal alignment of the upper and lower incisor teeth, usually resulting in malocclusion; in gnawing rodents, where incisors are rootless and grow continually, signs of incisor malocclusion include uneven wear patterns, sloping of the cutting edges, fractured teeth, altered pigmentation, and obvious pathological overgrowth of the incisors" [HP:0011062, https://books.google.com/books?isbn=0323394302, PMID:19622764] |
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Allelic Composition: Foxg1tm1(tTA)Lai/Foxg1tm1M,Tg(tetO-Foxg1)1Lai/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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