ENSMUSG00000026141


Mus musculus

Features
Gene ID: ENSMUSG00000026141
  
Biological name :Col19a1
  
Synonyms : Col19a1 / Collagen alpha-1(XIX) chain / Q0VF58
  
Possible biological names infered from orthology : collagen type XIX alpha 1 chain / Q14993
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: A5
Gene start: 24261890
Gene end: 24587472
  
Corresponding Affymetrix probe sets: 10353574 (MoGene1.0st)   1421698_a_at (Mouse Genome 430 2.0 Array)   1430676_at (Mouse Genome 430 2.0 Array)   1456953_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052606
Ensembl peptide - ENSMUSP00000110899
NCBI entrez gene - 12823     See in Manteia.
MGI - MGI:1095415
RefSeq - XM_006495646
RefSeq - NM_007733
RefSeq - XM_006495643
RefSeq - XM_006495644
RefSeq - XM_006495645
RefSeq - XM_006495642
RefSeq Peptide - NP_031759
swissprot - Q0VF58
swissprot - F8WHV4
Ensembl - ENSMUSG00000026141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COL19A1ENSGALG00000043584Gallus gallus
 Q14993ENSG00000082293Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Col22a1 / collagen, type XXII, alpha 1 / Q8NFW1* / collagen type XXII alpha 1 chain*ENSMUSG0000007902239
Col4a5 / collagen, type IV, alpha 5 / P29400* / collagen type IV alpha 5 chain*ENSMUSG0000003127438
Col4a4 / Q9QZR9 / Collagen alpha-4(IV) chain / P53420* / collagen type IV alpha 4 chain*ENSMUSG0000006715837
Col4a6 / collagen, type IV, alpha 6 / Q14031* / collagen type IV alpha 6 chain*ENSMUSG0000003127336
Q8BLX7 / Col16a1 / Collagen alpha-1(XVI) chain / Q07092* / collagen type XVI alpha 1 chain*ENSMUSG0000004069035
Col4a1 / P02463 / Collagen alpha-1(IV) chain Arresten / P02462* / collagen type IV alpha 1 chain*ENSMUSG0000003150235
Col4a2 / P08122 / Collagen alpha-2(IV) chain Canstatin / P08572* / collagen type IV alpha 2 chain*ENSMUSG0000003150334
Col4a3 / Q9QZS0 / Collagen alpha-3(IV) chain Tumstatin / Q01955* / collagen type IV alpha 3 chain*ENSMUSG0000007946534


Protein motifs (from Interpro)
Interpro ID Name
 IPR001791  Laminin G domain
 IPR008160  Collagen triple helix repeat
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR016133  Insect cysteine-rich antifreeze protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007517 muscle organ development IEA
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030198 extracellular matrix organization IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000418 patchy hair "uneven spots of hair growth on the body" [J:26975]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0000467 abnormal esophagus morphology "malformation of the part of the digestive canal through which food passes from the pharynx to the stomach" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0003157 impaired muscle relaxation "reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0003158 dysphagia "difficulty in swallowing food or liquid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

 MP:0003159 abnormal esophageal smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue lining the esophagus" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

 MP:0003160 abnormal esophageal development "aberrant formation of the part of the digestive canal through which food passes from the pharynx to the stomach" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

 MP:0004548 dilated esophagus "an expansion in the lumen volume of the part of the digestive canal through which food passes from the pharynx to the stomach" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

 MP:0005202 lethargy "mild impairment of consciousness resulting in reduced alertness and awareness; ultimately due to generalized brain dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Col19a1tm2Rmz/Col19a1tm2Rmz
Genetic Background: involves: 129T2/SvEmsJ

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: KitW-42J/KitW-42J
Genetic Background: C57BL/6J-KitW-42J/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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