ENSMUSG00000031502


Mus musculus

Features
Gene ID: ENSMUSG00000031502
  
Biological name :Col4a1
  
Synonyms : Col4a1 / Collagen alpha-1(IV) chain Arresten / P02463
  
Possible biological names infered from orthology : collagen type IV alpha 1 chain / P02462
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A1.1
Gene start: 11198423
Gene end: 11312826
  
Corresponding Affymetrix probe sets: 10576973 (MoGene1.0st)   1426348_at (Mouse Genome 430 2.0 Array)   1452035_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033898
Ensembl peptide - ENSMUSP00000148226
Ensembl peptide - ENSMUSP00000147951
Ensembl peptide - ENSMUSP00000147459
Ensembl peptide - ENSMUSP00000146554
NCBI entrez gene - 12826     See in Manteia.
MGI - MGI:88454
RefSeq - XM_017312555
RefSeq - NM_009931
RefSeq Peptide - NP_034061
swissprot - A0A140LHU8
swissprot - A0A1B0GSI7
swissprot - A0A1B0GT69
swissprot - P02463
swissprot - A0A1B0GRC0
Ensembl - ENSMUSG00000031502
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col4a1ENSDARG00000055009Danio rerio
 COL4A1ENSGALG00000036798Gallus gallus
 COL4A1ENSG00000187498Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Col4a5 / collagen, type IV, alpha 5 / P29400* / collagen type IV alpha 5 chain*ENSMUSG0000003127462
Col4a3 / Q9QZS0 / Collagen alpha-3(IV) chain Tumstatin / Q01955* / collagen type IV alpha 3 chain*ENSMUSG0000007946552
Col4a2 / P08122 / Collagen alpha-2(IV) chain Canstatin / P08572* / collagen type IV alpha 2 chain*ENSMUSG0000003150348
Col4a6 / collagen, type IV, alpha 6 / Q14031* / collagen type IV alpha 6 chain*ENSMUSG0000003127346
Col4a4 / Q9QZR9 / Collagen alpha-4(IV) chain / P53420* / collagen type IV alpha 4 chain*ENSMUSG0000006715846
Col22a1 / collagen, type XXII, alpha 1 / Q8NFW1* / collagen type XXII alpha 1 chain*ENSMUSG0000007902233
Q8BLX7 / Col16a1 / Collagen alpha-1(XVI) chain / Q07092* / collagen type XVI alpha 1 chain*ENSMUSG0000004069032
Q0VF58 / Col19a1 / Collagen alpha-1(XIX) chain / Q14993* / collagen type XIX alpha 1 chain*ENSMUSG0000002614124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001442  Collagen IV, non-collagenous
 IPR008160  Collagen triple helix repeat
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR016187  C-type lectin fold
 IPR036954  Collagen IV, non-collagenous domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0007528 neuromuscular junction development IMP
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IGI
 biological_processGO:0048514 blood vessel morphogenesis IEA
 biological_processGO:0061304 retinal blood vessel morphogenesis IEA
 biological_processGO:0061333 renal tubule morphogenesis IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 biological_processGO:0071711 basement membrane organization IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005587 collagen type IV trimer IEA
 cellular_componentGO:0005604 basement membrane IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA
 molecular_functionGO:0048407 platelet-derived growth factor binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Signaling by PDGF
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Laminin interactions
Non-integrin membrane-ECM interactions
NCAM1 interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: KitWads/Kit+
Genetic Background: involves: C57BL/6J

Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1ENU6009/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6009

Allelic Composition: Col4a1ENU6019/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6019

Allelic Composition: Col4a1ENU6024/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6024

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0000528 delayed kidney development "late onset of the induction and/or differentiation of the kidney" [J:18048]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J * CAST/EiJ

 MP:0000752 dystrophic muscle "progressive weakness and wasting of muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67994]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0000791 delaminated cerebral cortex "splitting of the layers of the gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:38857]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
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Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0001312 abnormal cornea morphology "malformation or absence of the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0001314 corneal opacity "complete or partial clouding of the cornea" [jte:Janan T. Eppig , Mouse Genome Informatics, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

 MP:0001319 irregularly shaped pupil "shape defects in the aperture of the iris through which light rays enter the eye, usually circular " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0001322 abnormal iris morphology "structural anomaly of the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

 MP:0001325 abnormal retina morphology "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Pde6brd1-4H/Pde6brd1-4H
Genetic Background: involves: BALB/cAnN * C3H/HeN

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0001762 polyuria "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0001859 kidney inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0001916 intracerebral hemorrhage "bleeding within the cerebrum" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0002064 seizures "sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0002136 abnormal kidney physiology "altered ability or inability to excrete urine, not due to anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0002792 abnormal retinal vascularization "malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0002828 abnormal glomerular capsule "anomalous structure or development of the expanded beginning of a nephron that contains the glomerulus" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0002871 albuminuria "presence of excess albumin in the urine" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: KitWads/Kit+
Genetic Background: involves: C57BL/6J

Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1ENU6009/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6009

Allelic Composition: Col4a1ENU6019/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6019

Allelic Composition: Col4a1ENU6024/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6024

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: KitWads/Kit+
Genetic Background: involves: C57BL/6J

Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1ENU6009/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6009

Allelic Composition: Col4a1ENU6019/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6019

Allelic Composition: Col4a1ENU6024/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6024

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0002959 increased microalbumin excretion "greater than the normal amount of fragments of this protein voided by the kidneys" [RGD:Rat Genome Database submission]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0002988 decreased urine osmolarity "reduction in the concentration of ions in the urine compared to normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:83000]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0003236 abnormal lens capsule morphology "malformation in the elastic, clear, membrane-like structure, that is outer most layer of the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
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Allelic Composition: KitWads/Kit+
Genetic Background: involves: C57BL/6J

Allelic Composition: Col4a1F247/Col4a1+
Genetic Background: C3.Cg-Col4a1F247

 MP:0003354 astrocytosis "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0003381 vitreal fibroplasia "production of excess fibrous tissue in the vitreous body of the eye" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0003954 abnormal Reichert s membrane "aberrant structure of the extraembryonic basement membrane that forms on the inner surface of the trophectoderm beginning at E6.0 and is secreted by the distal endoderm; required for the maternofetal exchange of nutrients and is important for the postgastrulation development" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0004193 abnormal kidney papilla morphology "any structural anomaly of the apex of the renal pyramid that projects into a calyx" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0004272 abnormal basement membrane morphology "anomaly in the structure, organization and/or placement of the extracellular supportive tissue adjacent to the basal surface of the epithelia, including the epithelium of muscle cells, fat cells and Schwann cells; it is comprised of type IV collagen, laminin, and sulfated proteoglycans and other components and consists of two layers, the basal lamina and the lamina reticularis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A10.272.220]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0004754 abnormal kidney collecting duct "any structural anomaly of the duct that drains fluid from the nephron and either allows bodily reabsorbtion of water or allows the fluid to drain to the bladder via the ureter; the collecting duct system also maintains acid-base homeostasis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0004756 abnormal proximal convoluted tubule morphology "any structural anomaly of the convoluted portion of the duct system of the nephron that extends from the renal glomeurlar capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle; fluid entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0004860 dilated kidney collecting duct "stretched or widened aperture of the luminal space of the collecting ducts" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0005161 hematuria "presence of blood in the urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:78193]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005325 abnormal glomerulus "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0005326 abnormal podocytes "anomalous structure of the foot processes of the epithelial cells of the glomerulus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57971]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005542 corneal vascularization "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0006051 brainstem hemorrhage "bleeding into the brain stem" [smb:Susan M Bello, Mouse Genome Informatics Curator, RGD:Rat Genome Database submission]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0006069 abnormal retinal neuronal layer morphology "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0006203 eye hemorrhage "bleeding into the eye" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

 MP:0006221 optic nerve hypoplasia "less than the normal number of fibers in the optic nerve" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0008056 abnormal retinal ganglion cell morphology "any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0008059 abnormal podocyte foot process morphology "any structural anomaly of the footlike extension of podocytes that interdigitate with one another to form the walls of the glomerular capillaries" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008060 abnormal podocyte slit diaphragm morphology "any structural anomaly of the thin membrane that covers the podocyte filtration slit which allows small molecules such as water, glucose, and ionic salts to pass through while retaining larger macromolecules in the bloodstream" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0008140 podocyte foot process effacement "thinning of the footlike extension of podocytes that interdigitate with one another to form the walls of the glomerular capillaries" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0009026 abnormal brain pia mater morphology "any structural anomaly of the fibrous membrane forming the innermost of the three coverings that surrounds the brain within the cranial cavity that is firmly attached to the glial capsule" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0009050 dilated proximal convoluted tubules "stretched or widened aperture of the luminal space of the convoluted portion of the duct system of the nephron that extends from the renal glomerular capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Clcn7tm2.1Mjec/Clcn7tm2.1Mjec
Genetic Background: D2.129(Cg)-Clcn7tm2.1Mjec

 MP:0009274 buphthalmos "abnormal enlargement of the eye that is usually congenital and attended by symptoms of glaucoma" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0009275 bruising "an injury to biological tissue in which the capillaries are damaged, allowing blood to seep into the surrounding tissue; it should not be confused with ecchymosis, though the terms are related" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

Allelic Composition: Col4a1Raw/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0010090 increased circulating creatine kinase level "an elevation in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0010098 abnormal retinal blood vessel pattern "anomaly in the systematic arrangement of the blood vessels supplying the retina" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0010235 abnormal retina inner limiting membrane morphology "any structural anomaly of the row of fused Muller cell processes and astrocytes that separates the retinal nerve fiber layer from the vitreous" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0010252 anterior subcapsular cataracts "a lens opacity localized beneath the anterior lens capsule" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0010259 anterior polar cataracts "a lens opacity, usually disk-shaped, that is limited to an area in the anterior pole of the lens capsular region" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1ENU6009/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6009

Allelic Composition: Col4a1ENU6019/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6019

Allelic Composition: Col4a1ENU6024/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6024

 MP:0010261 sutural cataracts "a lens opacity which follows the shape of anterior or posterior Y suture of the fetal lens and is not progressive; often more severe in males and is congenital, but usually does not affect vision" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: KitWads/Kit+
Genetic Background: involves: C57BL/6J

 MP:0010263 total cataracts "a lens opacity which involves both nuclear and cortical regions, including all fibers of a lens; usually congenital" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: B6.129S-Col4a1deltaex40

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
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Allelic Composition: Dnm1Ftfl/Dnm1Ftfl,Tg(Pvalb-EGFP)B20Zjh/0
Genetic Background: involves: C57BL/6 * C57BL/6J * FVB

Allelic Composition: Col4a1ENU911/Col4a1ENU911
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1ENU4004
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1ENU6005
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1ENU6009/Col4a1ENU6009
Genetic Background: C3H/HeJ-Col4a1ENU6009

Allelic Composition: Col4a1D456/Col4a1D456
Genetic Background: C3.D2-Col4a1D456

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011187 abnormal parietal endoderm morphology "any structural anomaly of the primitive endoderm-derived tissue that lines the luminal surface of the mural trophectoderm" [PMID:19201946]
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Allelic Composition: Nbntm2Zqw/Nbntm2Zqw,Trp53tm1Brd/Trp53tm1Brd,Tg(Nes-cre)1Wme/0
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * CBA

 MP:0011339 abnormal glomerular mesangium morphology "any structural anomaly of the inner layer of the glomerulus within the basement membrane surrounding the glomerular capillaries that contain the intraglomerular mesangial cells" [MGI:csmith]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011348 abnormal renal glomerulus basement membrane morphology "any structural anomaly of the layer of extracellular matrix that lies between the endothelium of the glomerular capillaries and the podocytes of the inner or visceral layer of the Bowman capsule; it is a fusion of the endothelial cell and podocyte basal laminas and acts as a physical barrier and an ion-selective filter" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011380 enlarged brain ventricle "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb]
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Allelic Composition: Col4a1deltaex40/Col4a1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0011402 renal cast "any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011419 erythrocyturia "presence of red blood cells in the urine" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011481 anterior iris synechia "adhesion of the iris to the cornea" [MGI:anna]
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Allelic Composition: Gdf5brp/Gdf5brp
Genetic Background: NC

Allelic Composition: Col4a1Svc/Col4a1+
Genetic Background: involves: BALB/cAnN * C3H/HeN

 MP:0011498 abnormal glomerular capsule parietal layer morphology "any structural anomaly of the outer layer of the glomerular capsule composed of a single layer of simple squamous epithelium" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011501 increased glomerular capsule space "increased volume of the luminal region between the glomerular capsule visceral and parietal layers, into which filtrate enters after passing through the filtration barrier from the glomerular capillaries" [MGI:csmith]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011502 parietal capsular epithelium metaplasia "a metaplastic change or transformation of the single layer of the parietal epithelium of Bowman s capsule from the normal structural appearance of simple squamous epithelium to a cuboidal or low columnar epithelium; also referred to as a prominent parietal epithelium" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011509 dilated glomerular capillary "stretched or widened aperture of the luminal space of the small branching blood vessel in the kidney glomerulus that receives blood from the kidney afferent arteriole" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011682 renal glomerulus cysts "abnormal membranous sacs in any portion of the renal glomerulus" [MGI:csmith]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0011697 vacuolated lens "fluid filled cavities are present in the cytoplasm of the transparent structure of the eye responsible for focusing light" [MGI:llw2]
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Allelic Composition: Col4a1ENU911/Col4a1+
Genetic Background: C3.Cg-Col4a1ENU911

Allelic Composition: Col4a1ENU4004/Col4a1+
Genetic Background: C3.D2-Col4a1ENU4004

Allelic Composition: Col4a1ENU6005/Col4a1+
Genetic Background: C3H/HeJ-Col4a1ENU6005

Allelic Composition: Col4a1D456/Col4a1+
Genetic Background: C3.D2-Col4a1D456

 MP:0011843 abnormal kidney collecting duct epithelium morphology "any structural anomaly of the simple cuboidal epithelium lining the lumen of kidney collecting ducts; the mature and differentiated CD epithelium comprises two unique cells types with principal cells responsible for vasopressin-regulated water reabsorption, and intercalated cells regulating acid-base homeostasis; injury to the epithelium is believed to cause epithelial cells to acquire mesenchymal characteristics via epithelial-mesenchymal transition (EMT), a process through which tubular epithelial cells may transform into interstitial fibroblasts and promote renal fibrosis" [MGI:anna]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0020153 abnormal urine albumin level "anomaly in the amount of albumin in the urine" [GOC:NV]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0020254 decreased collagen level "decreased level of the main structural protein of the various connective tissues in animals" [GOC:NV, PMID:11704682]
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Allelic Composition: Col4a1tm1.1Ics/Col4a1tm1.1Ics
Genetic Background: involves: 129S2/SvPas * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031503 Col4a2 / P08122 / Collagen alpha-2(IV) chain Canstatin / P08572* / collagen type IV alpha 2 chain*  / complex / -
 ENSMUSG00000031502 Col4a1 / P02463 / Collagen alpha-1(IV) chain Arresten / P02462* / collagen type IV alpha 1 chain*  / - / complex
 ENSMUSG00000002900 Lamb1 / P02469 / Laminin subunit beta-1 / P07942*  / reaction / complex
 ENSMUSG00000025044 Msr1 / P30204 / Macrophage scavenger receptor types I and II / P21757* / macrophage scavenger receptor 1*  / reaction / complex
 ENSMUSG00000031273 Col4a6 / collagen, type IV, alpha 6 / Q14031* / collagen type IV alpha 6 chain*  / -
 ENSMUSG00000031274 Col4a5 / collagen, type IV, alpha 5 / P29400* / collagen type IV alpha 5 chain*  / -






 

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