ENSMUSG00000031273


Mus musculus

Features
Gene ID: ENSMUSG00000031273
  
Biological name :Col4a6
  
Synonyms : Col4a6 / collagen, type IV, alpha 6
  
Possible biological names infered from orthology : collagen type IV alpha 6 chain / Q14031
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F2
Gene start: 141165403
Gene end: 141474076
  
Corresponding Affymetrix probe sets: 10607012 (MoGene1.0st)   1421006_at (Mouse Genome 430 2.0 Array)   1421007_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098765
NCBI entrez gene - 94216     See in Manteia.
MGI - MGI:2152695
RefSeq - NM_053185
RefSeq - XM_011247883
RefSeq Peptide - NP_444415
swissprot - B1AVK5
Ensembl - ENSMUSG00000031273
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 col4a6ENSDARG00000052061Danio rerio
 COL4A6ENSGALG00000008266Gallus gallus
 COL4A6ENSG00000197565Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Col4a4 / Q9QZR9 / Collagen alpha-4(IV) chain / P53420* / collagen type IV alpha 4 chain*ENSMUSG0000006715850
Col4a2 / P08122 / Collagen alpha-2(IV) chain Canstatin / P08572* / collagen type IV alpha 2 chain*ENSMUSG0000003150350
Col4a5 / collagen, type IV, alpha 5 / P29400* / collagen type IV alpha 5 chain*ENSMUSG0000003127448
Col4a3 / Q9QZS0 / Collagen alpha-3(IV) chain Tumstatin / Q01955* / collagen type IV alpha 3 chain*ENSMUSG0000007946546
Col4a1 / P02463 / Collagen alpha-1(IV) chain Arresten / P02462* / collagen type IV alpha 1 chain*ENSMUSG0000003150245
Q8BLX7 / Col16a1 / Collagen alpha-1(XVI) chain / Q07092* / collagen type XVI alpha 1 chain*ENSMUSG0000004069031
Col22a1 / collagen, type XXII, alpha 1 / Q8NFW1* / collagen type XXII alpha 1 chain*ENSMUSG0000007902231
Q0VF58 / Col19a1 / Collagen alpha-1(XIX) chain / Q14993* / collagen type XIX alpha 1 chain*ENSMUSG0000002614124


Protein motifs (from Interpro)
Interpro ID Name
 IPR001442  Collagen IV, non-collagenous
 IPR008160  Collagen triple helix repeat
 IPR016133  Insect cysteine-rich antifreeze protein
 IPR016187  C-type lectin fold
 IPR036954  Collagen IV, non-collagenous domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030198 extracellular matrix organization IDA
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway IGI
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005581 collagen trimer IEA
 cellular_componentGO:0005587 collagen type IV trimer IDA
 cellular_componentGO:0005604 basement membrane IDA
 molecular_functionGO:0005198 structural molecule activity IDA
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Extracellular matrix organization
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Integrin cell surface interactions
Anchoring fibril formation
Crosslinking of collagen fibrils
Laminin interactions
Non-integrin membrane-ECM interactions
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr2tm1Dor/Fgfr2tm1Dor,Lamb2tm1Jrs/Lamb2tm1Jrs,Tg(Mnx1-cre)1Jrs/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031503 Col4a2 / P08122 / Collagen alpha-2(IV) chain Canstatin / P08572* / collagen type IV alpha 2 chain*  / -
 ENSMUSG00000031273 Col4a6 / collagen, type IV, alpha 6 / Q14031* / collagen type IV alpha 6 chain*  / -
 ENSMUSG00000031502 Col4a1 / P02463 / Collagen alpha-1(IV) chain Arresten / P02462* / collagen type IV alpha 1 chain*  / -
 ENSMUSG00000031274 Col4a5 / collagen, type IV, alpha 5 / P29400* / collagen type IV alpha 5 chain*  / - / complex






 

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