ENSMUSG00000026589


Mus musculus

Features
Gene ID: ENSMUSG00000026589
  
Biological name :Sec16b
  
Synonyms : Protein transport protein Sec16B / Q91XT4 / Sec16b
  
Possible biological names infered from orthology : Q96JE7 / SEC16 homolog B, endoplasmic reticulum export factor
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H1
Gene start: 157506728
Gene end: 157568425
  
Corresponding Affymetrix probe sets: 10350864 (MoGene1.0st)   1450734_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027881
Ensembl peptide - ENSMUSP00000083300
Ensembl peptide - ENSMUSP00000107329
Ensembl peptide - ENSMUSP00000119359
NCBI entrez gene - 89867     See in Manteia.
MGI - MGI:2148802
RefSeq - XM_017312986
RefSeq - NM_001159986
RefSeq - NM_033354
RefSeq - XM_006497049
RefSeq - XM_017312983
RefSeq - XM_017312984
RefSeq Peptide - NP_001153458
RefSeq Peptide - NP_203505
swissprot - F6Q2Y9
swissprot - Q91XT4
Ensembl - ENSMUSG00000026589
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec16bENSDARG00000099554Danio rerio
 SEC16BENSGALG00000004424Gallus gallus
 Q96JE7ENSG00000120341Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sec16a / SEC16 homolog A, endoplasmic reticulum export factor / O15027*ENSMUSG0000002692432


Protein motifs (from Interpro)
Interpro ID Name
 IPR024298  Ancestral coatomer element 1, Sec16/Sec31
 IPR024340  Sec16, central conserved domain
 IPR024880  COPII coat assembly protein, Sec16


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007029 endoplasmic reticulum organization ISO
 biological_processGO:0007031 peroxisome organization ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0016559 peroxisome fission ISO
 biological_processGO:0048208 COPII vesicle coating IEA
 biological_processGO:0070863 positive regulation of protein exit from endoplasmic reticulum ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000183 decreased circulating LDL cholesterol level "less than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rnf10tm1a(KOMP)Wtsi/Rnf10tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1a(KOMP)Wtsi/Wtsi

 MP:0000186 decreased circulating HDL cholesterol level "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rnf10tm1a(KOMP)Wtsi/Rnf10tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1a(KOMP)Wtsi/Wtsi

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Rnf10tm1a(KOMP)Wtsi/Rnf10tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1a(KOMP)Wtsi/Wtsi

 MP:0005179 decreased total circulating cholesterol level "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Rnf10tm1a(KOMP)Wtsi/Rnf10tm1a(KOMP)Wtsi
Genetic Background: C57BL/6N-Rnf10tm1a(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001052 Sec24b / Sec24 related gene family, member B (S. cerevisiae) / O95487* / SEC24 homolog B, COPII coat complex component*  / complex / reaction
 ENSMUSG00000020386 Sar1b / Q9CQC9 / secretion associated Ras related GTPase 1B / Q9Y6B6*  / complex / reaction
 ENSMUSG00000020986 Q01405 / Sec23a / Protein transport protein Sec23A / Q15436* / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSMUSG00000035325 Q3UPL0 / Sec31a / Protein transport protein Sec31A / O94979* / SEC31 homolog A, COPII coat complex component*  / complex / reaction
 ENSMUSG00000055319 Sec23ip / Sec23 interacting protein / Q9Y6Y8*  / complex / reaction
 ENSMUSG00000027879 O08547 / Sec22b / Vesicle-trafficking protein SEC22b / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / complex / reaction
 ENSMUSG00000026924 Sec16a / SEC16 homolog A, endoplasmic reticulum export factor / O15027*  / complex
 ENSMUSG00000030298 Sec13 / Q9D1M0 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735*  / complex / reaction
 ENSMUSG00000036391 Q3U2P1 / Sec24a / Protein transport protein Sec24A / O95486* / SEC24 homolog A, COPII coat complex component*  / complex / reaction
 ENSMUSG00000039234 Sec24d / Sec24 related gene family, member D (S. cerevisiae) / O94855* / SEC24 homolog D, COPII coat complex component*  / complex / reaction






 

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