ENSG00000120341


Homo sapiens

Features
Gene ID: ENSG00000120341
  
Biological name :SEC16B
  
Synonyms : Q96JE7 / SEC16B / SEC16 homolog B, endoplasmic reticulum export factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q25.2
Gene start: 177923956
Gene end: 177984303
  
Corresponding Affymetrix probe sets: 1552880_at (Human Genome U133 Plus 2.0 Array)   1555289_at (Human Genome U133 Plus 2.0 Array)   1564423_a_at (Human Genome U133 Plus 2.0 Array)   228150_at (Human Genome U133 Plus 2.0 Array)   239618_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000475522
Ensembl peptide - ENSP00000308339
Ensembl peptide - ENSP00000431727
Ensembl peptide - ENSP00000435101
NCBI entrez gene - 89866     See in Manteia.
OMIM - 612855
RefSeq - NM_033127
RefSeq - NM_001356499
RefSeq Peptide - NP_001343428
RefSeq Peptide - NP_149118
swissprot - U3KQ39
swissprot - E9PK14
swissprot - H0YE70
swissprot - Q96JE7
Ensembl - ENSG00000120341
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec16bENSDARG00000099554Danio rerio
 SEC16BENSGALG00000004424Gallus gallus
 Q91XT4ENSMUSG00000026589Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15027 / SEC16A / SEC16 homolog A, endoplasmic reticulum export factorENSG0000014839632


Protein motifs (from Interpro)
Interpro ID Name
 IPR024298  Ancestral coatomer element 1, Sec16/Sec31
 IPR024340  Sec16, central conserved domain
 IPR024880  COPII coat assembly protein, Sec16


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007029 endoplasmic reticulum organization IDA
 biological_processGO:0007031 peroxisome organization IDA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0016559 peroxisome fission IMP
 biological_processGO:0048208 COPII vesicle coating IEA
 biological_processGO:0070863 positive regulation of protein exit from endoplasmic reticulum IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114354 TFG / Q92734 / TRK-fused gene  / reaction / complex
 ENSG00000138802 O95487 / SEC24B / SEC24 homolog B, COPII coat complex component  / reaction / complex
 ENSG00000138674 O94979 / SEC31A / SEC31 homolog A, COPII coat complex component  / complex / reaction
 ENSG00000148396 O15027 / SEC16A / SEC16 homolog A, endoplasmic reticulum export factor  / complex
 ENSG00000100934 Q15436 / SEC23A / Sec23 homolog A, coat complex II component  / reaction / complex
 ENSG00000150961 O94855 / SEC24D / SEC24 homolog D, COPII coat complex component  / complex / reaction
 ENSG00000157020 SEC13 / P55735 / SEC13 homolog, nuclear pore and COPII coat complex component  / reaction / complex
 ENSG00000176986 P53992 / SEC24C / SEC24 homolog C, COPII coat complex component  / complex / reaction
 ENSG00000113615 O95486 / SEC24A / SEC24 homolog A, COPII coat complex component  / reaction / complex
 ENSG00000107651 Q9Y6Y8 / SEC23IP / SEC23 interacting protein  / complex / reaction
 ENSG00000152700 SAR1B / Q9Y6B6 / secretion associated Ras related GTPase 1B  / reaction / complex
 ENSG00000265808 O75396 / SEC22B / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)  / complex / reaction






 

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