ENSMUSG00000035325


Mus musculus

Features
Gene ID: ENSMUSG00000035325
  
Biological name :Sec31a
  
Synonyms : Protein transport protein Sec31A / Q3UPL0 / Sec31a
  
Possible biological names infered from orthology : O94979 / SEC31 homolog A, COPII coat complex component
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E4
Gene start: 100361649
Gene end: 100416234
  
Corresponding Affymetrix probe sets: 10531675 (MoGene1.0st)   1453014_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092157
Ensembl peptide - ENSMUSP00000138507
Ensembl peptide - ENSMUSP00000138571
Ensembl peptide - ENSMUSP00000138129
Ensembl peptide - ENSMUSP00000138213
Ensembl peptide - ENSMUSP00000138366
Ensembl peptide - ENSMUSP00000138428
NCBI entrez gene - 69162     See in Manteia.
MGI - MGI:1916412
RefSeq - XM_017321089
RefSeq - NM_026969
RefSeq - XM_011249558
RefSeq - XM_011249559
RefSeq - XM_011249560
RefSeq - XM_011249561
RefSeq - XM_011249562
RefSeq - XM_011249563
RefSeq - XM_017321088
RefSeq - XM_006535192
RefSeq - XM_006535193
RefSeq - XM_006535194
RefSeq - XM_006535207
RefSeq - XM_011249551
RefSeq - XM_011249552
RefSeq - XM_011249553
RefSeq - XM_011249554
RefSeq - XM_011249555
RefSeq - XM_011249556
RefSeq - XM_011249557
RefSeq Peptide - NP_081245
swissprot - S4R192
swissprot - S4R1T5
swissprot - Q3UPL0
swissprot - S4R256
swissprot - S4R2A9
swissprot - S4R1Y8
Ensembl - ENSMUSG00000035325
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec31aENSDARG00000021082Danio rerio
 SEC31AENSGALG00000040484Gallus gallus
 O94979ENSG00000138674Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3TZ89 / Sec31b / Protein transport protein Sec31B / Q9NQW1* / SEC31 homolog B, COPII coat complex component*ENSMUSG0000005198443


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR024298  Ancestral coatomer element 1, Sec16/Sec31
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0051592 response to calcium ion ISO
 biological_processGO:0090110 cargo loading into COPII-coated vesicle ISO
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0012507 ER to Golgi transport vesicle membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030120 vesicle coat ISO
 cellular_componentGO:0030127 COPII vesicle coat ISS
 cellular_componentGO:0030134 COPII-coated ER to Golgi transport vesicle ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0070971 endoplasmic reticulum exit site ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding ISO


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
MHC class II antigen presentation
Antigen Presentation: Folding, assembly and peptide loading of class I MHC


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001052 Sec24b / Sec24 related gene family, member B (S. cerevisiae) / O95487* / SEC24 homolog B, COPII coat complex component*  / reaction / complex
 ENSMUSG00000020386 Sar1b / Q9CQC9 / secretion associated Ras related GTPase 1B / Q9Y6B6*  / complex / reaction
 ENSMUSG00000025162 Csnk1d / Q9DC28 / casein kinase 1, delta / P48730*  / reaction
 ENSMUSG00000020986 Q01405 / Sec23a / Protein transport protein Sec23A / Q15436* / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSMUSG00000026589 Q91XT4 / Sec16b / Protein transport protein Sec16B / Q96JE7* / SEC16 homolog B, endoplasmic reticulum export factor*  / complex / reaction
 ENSMUSG00000036594 H2-Aa / P14434 / H-2 class II histocompatibility antigen, A-B alpha chain / P01909* / P01906* / HLA-DQA2* / HLA-DQA1* / major histocompatibility complex, class II, DQ alpha 2* / major hist...  / complex / reaction
 ENSMUSG00000030298 Sec13 / Q9D1M0 / SEC13 homolog, nuclear pore and COPII coat complex component / P55735*  / complex / reaction
 ENSMUSG00000055319 Sec23ip / Sec23 interacting protein / Q9Y6Y8*  / complex
 ENSMUSG00000073421 H2-Ab1 / P14483 / histocompatibility 2, class II antigen A, beta 1 / P05538* / HLA-DQB1* / HLA-DQB2* / major histocompatibility complex, class II, DQ beta 1* / major histocompatibility comp...  / complex / reaction
 ENSMUSG00000036391 Q3U2P1 / Sec24a / Protein transport protein Sec24A / O95486* / SEC24 homolog A, COPII coat complex component*  / reaction / complex
 ENSMUSG00000024610 Cd74 / P04441 / CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) / P04233* / CD74 molecule*  / complex / reaction
 ENSMUSG00000067341 H2-Eb2 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / complex / reaction
 ENSMUSG00000039234 Sec24d / Sec24 related gene family, member D (S. cerevisiae) / O94855* / SEC24 homolog D, COPII coat complex component*  / complex / reaction
 ENSMUSG00000026924 Sec16a / SEC16 homolog A, endoplasmic reticulum export factor / O15027*  / complex / reaction
 ENSMUSG00000002546 Golga2 / Q921M4 / golgi autoantigen, golgin subfamily a, 2 / A7E2F4* / A8MQT2* / D6RF30* / F8WBI6* / A6NCC3* / A6NDK9* / A6NDN3* / A6NMD2* / H3BSY2* / I6L899* / P0CG33* / P0CJ92* / Q08379* ...  / complex / reaction
 ENSMUSG00000027879 O08547 / Sec22b / Vesicle-trafficking protein SEC22b / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / complex / reaction
 ENSMUSG00000035325 Q3UPL0 / Sec31a / Protein transport protein Sec31A / O94979* / SEC31 homolog A, COPII coat complex component*  / complex
 ENSMUSG00000060802 B2m / P01887 / Beta-2-microglobulin / P61769*  / complex / reaction
 ENSMUSG00000032513 Q91X51 / Gorasp1 / golgi reassembly stacking protein 1 / Q9BQQ3*  / reaction / complex
 ENSMUSG00000020149 Rab1 / P62821 / Ras-related protein Rab-1A / RAB1A* / P62820* / RAB1A, member RAS oncogene family*  / complex / reaction
 ENSMUSG00000060586 H2-Eb1 / Q9GIY3* / P01911* / P04229* / Q29974* / Q30154* / HLA-DRB5* / HLA-DRB1* / major histocompatibility complex, class II, DR beta 1* / major histocompatibility complex, class II, DR beta 5*  / reaction / complex
 ENSMUSG00000029407 Uso1 / Q9Z1Z0 / USO1 vesicle docking factor / O60763* / USO1 vesicle transport factor*  / reaction / complex






 

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