ENSMUSG00000032852


Mus musculus

Features
Gene ID: ENSMUSG00000032852
  
Biological name :Rspo4
  
Synonyms : Q8BJ73 / Rspo4 / R-spondin-4
  
Possible biological names infered from orthology : Q2I0M5
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: G3
Gene start: 151842927
Gene end: 151874668
  
Corresponding Affymetrix probe sets: 10477035 (MoGene1.0st)   1453711_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041578
NCBI entrez gene - 228770     See in Manteia.
MGI - MGI:1924467
RefSeq - XM_006499308
RefSeq - NM_001040689
RefSeq Peptide - NP_001035779
swissprot - Q0P5Y9
swissprot - Q8BJ73
Ensembl - ENSMUSG00000032852
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rspo4ENSDARG00000038593Danio rerio
 RSPO4ENSGALG00000023640Gallus gallus
 RSPO4ENSG00000101282Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rspo2 / Q8BFU0 / Mus musculus R-spondin 2 (Rspo2), transcript variant 1, mRNA. / Q6UXX9* / R-spondin 2*ENSMUSG0000005192042
Rspo3 / Q2TJ95 / R-spondin-3 / Q9BXY4*ENSMUSG0000001988035
Rspo1 / R-spondin 1 / Q2MKA7*ENSMUSG0000002887134


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR006212  Furin-like repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0035878 nail development IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000041961 Znrf3 / Q5SSZ7 / zinc and ring finger 3 / Q9ULT6*  / complex / reaction
 ENSMUSG00000042793 Lgr6 / Q3UVD5 / Leucine-rich repeat-containing G-protein coupled receptor 6 / Q9HBX8*  / complex / reaction
 ENSMUSG00000034177 Rnf43 / Q5NCP0 / E3 ubiquitin-protein ligase RNF43 / Q68DV7* / ring finger protein 43*  / complex / reaction
 ENSMUSG00000050199 Lgr4 / A2ARI4 / Leucine-rich repeat-containing G-protein coupled receptor 4 / Q9BXB1*  / reaction / complex
 ENSMUSG00000020140 Lgr5 / Q9Z1P4 / Leucine-rich repeat-containing G-protein coupled receptor 5 / O75473*  / reaction / complex






 

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