ENSMUSG00000038145


Mus musculus

Features
Gene ID: ENSMUSG00000038145
  
Biological name :Snrk
  
Synonyms : Mus musculus SNF related kinase (Snrk), transcript variant 5, mRNA. / Q8VDU5 / Snrk
  
Possible biological names infered from orthology : Q9NRH2 / SNF related kinase
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 122117266
Gene end: 122169702
  
Corresponding Affymetrix probe sets: 10590445 (MoGene1.0st)   1425678_a_at (Mouse Genome 430 2.0 Array)   1448864_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114132
Ensembl peptide - ENSMUSP00000113906
Ensembl peptide - ENSMUSP00000117994
Ensembl peptide - ENSMUSP00000120582
Ensembl peptide - ENSMUSP00000119878
Ensembl peptide - ENSMUSP00000112919
NCBI entrez gene - 20623     See in Manteia.
MGI - MGI:108104
RefSeq - XM_006512003
RefSeq - NM_001164572
RefSeq - NM_001357774
RefSeq - NM_001357775
RefSeq - NM_001357776
RefSeq - NM_133741
RefSeq - XM_006511998
RefSeq - XM_006511999
RefSeq - XM_006512000
RefSeq - XM_006512002
RefSeq Peptide - NP_001158044
RefSeq Peptide - NP_001344704
RefSeq Peptide - NP_001344705
RefSeq Peptide - NP_598502
RefSeq Peptide - NP_001344703
swissprot - Q8VDU5
swissprot - D3Z3V0
swissprot - D3Z1F6
swissprot - D3YXV4
swissprot - D3YVW4
Ensembl - ENSMUSG00000038145
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snrkaENSDARG00000070832Danio rerio
 SNRKENSGALG00000039920Gallus gallus
 SNRKENSG00000163788Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mark3 / Q03141 / MAP/microtubule affinity-regulating kinase 3 / P27448* / microtubule affinity regulating kinase 3*ENSMUSG0000000741128
Mark1 / Q8VHJ5 / Serine/threonine-protein kinase MARK1 / Q9P0L2* / microtubule affinity regulating kinase 1*ENSMUSG0000002662028
Mark4 / Q8CIP4 / MAP/microtubule affinity-regulating kinase 4 / Q96L34* / microtubule affinity regulating kinase 4*ENSMUSG0000003039727
Mark2 / microtubule affinity regulating kinase 2 / Q7KZI7*ENSMUSG0000002496927
Sik3 / SIK family kinase 3ENSMUSG0000003413526
Sik1 / Q60670 / Serine/threonine-protein kinase SIK1 / SIK1B* / P57059* / salt inducible kinase 1* / salt inducible kinase 1B (putative)*ENSMUSG0000002404224
Sik2 / salt inducible kinase 2 / Q9H0K1*ENSMUSG0000003711223
Nim1k / Q8BHI9 / Serine/threonine-protein kinase NIM1 / Q8IY84* / NIM1 serine/threonine protein kinase*ENSMUSG0000009593018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

Allelic Composition: Snrktm2Rra/Snrktm2Rra,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * FVB/N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

Allelic Composition: Snrktm2Rra/Snrk+,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * FVB/N

 MP:0002644 decreased circulating triglyceride level "lower than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

 MP:0002702 decreased circulating free fatty acid level "lower than normal levels of unesterified fatty acids in the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

 MP:0003921 abnormal left ventricle morphology "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrktm2Rra/Snrktm2Rra,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * FVB/N

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

 MP:0005598 decreased ventricle muscle contractility "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Snrktm2Rra/Snrktm2Rra,Tg(Myh6-cre)2182Mds/0
Genetic Background: involves: C57BL/6J * FVB/N

 MP:0010579 increased heart left ventricle size "greater than average size of the left ventricle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Intudtm/Intutm1.2Aliu
Genetic Background: involves: 129P2/OlaHsd * C3H/HeN

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr