ENSMUSG00000026620


Mus musculus

Features
Gene ID: ENSMUSG00000026620
  
Biological name :Mark1
  
Synonyms : Mark1 / Q8VHJ5 / Serine/threonine-protein kinase MARK1
  
Possible biological names infered from orthology : microtubule affinity regulating kinase 1 / Q9P0L2
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H5
Gene start: 184896789
Gene end: 184999570
  
Corresponding Affymetrix probe sets: 10360863 (MoGene1.0st)   1419834_x_at (Mouse Genome 430 2.0 Array)   1425509_at (Mouse Genome 430 2.0 Array)   1425510_at (Mouse Genome 430 2.0 Array)   1425511_at (Mouse Genome 430 2.0 Array)   1449630_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027929
Ensembl peptide - ENSMUSP00000142314
NCBI entrez gene - 226778     See in Manteia.
MGI - MGI:2664902
RefSeq - XM_006497141
RefSeq - NM_145515
RefSeq - XM_006497139
RefSeq - XM_006497140
RefSeq Peptide - NP_663490
swissprot - A0A0A6YY78
swissprot - Q8VHJ5
Ensembl - ENSMUSG00000026620
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mark3bENSDARG00000026630Danio rerio
 MARK1ENSGALG00000009483Gallus gallus
 MARK1ENSG00000116141Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mark3 / Q03141 / MAP/microtubule affinity-regulating kinase 3 / P27448* / microtubule affinity regulating kinase 3*ENSMUSG0000000741169
Mark2 / microtubule affinity regulating kinase 2 / Q7KZI7*ENSMUSG0000002496967
Mark4 / Q8CIP4 / MAP/microtubule affinity-regulating kinase 4 / Q96L34* / microtubule affinity regulating kinase 4*ENSMUSG0000003039755
Sik3 / SIK family kinase 3ENSMUSG0000003413533
Sik2 / salt inducible kinase 2 / Q9H0K1*ENSMUSG0000003711228
Sik1 / Q60670 / Serine/threonine-protein kinase SIK1 / SIK1B* / P57059* / salt inducible kinase 1* / salt inducible kinase 1B (putative)*ENSMUSG0000002404228
Snrk / Q8VDU5 / Mus musculus SNF related kinase (Snrk), transcript variant 5, mRNA. / Q9NRH2* / SNF related kinase*ENSMUSG0000003814527
Nim1k / Q8BHI9 / Serine/threonine-protein kinase NIM1 / Q8IY84* / NIM1 serine/threonine protein kinase*ENSMUSG0000009593019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001772  Kinase associated domain 1 (KA1)
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR015940  Ubiquitin-associated domain
 IPR017441  Protein kinase, ATP binding site
 IPR028375  KA1 domain/Ssp2, C-terminal
 IPR033627  Serine/threonine-protein kinase MARK1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030010 establishment of cell polarity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0001786 phosphatidylserine binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050321 tau-protein kinase activity ISS
 molecular_functionGO:0070300 phosphatidic acid binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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