ENSMUSG00000038975


Mus musculus

Features
Gene ID: ENSMUSG00000038975
  
Biological name :Rabggtb
  
Synonyms : P53612 / Rab geranylgeranyl transferase, b subunit / Rabggtb
  
Possible biological names infered from orthology : P53611 / Rab geranylgeranyltransferase beta subunit
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: H3
Gene start: 153907287
Gene end: 153913009
  
Corresponding Affymetrix probe sets: 10502934 (MoGene1.0st)   10502949 (MoGene1.0st)   1419553_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142999
Ensembl peptide - ENSMUSP00000143701
Ensembl peptide - ENSMUSP00000143567
Ensembl peptide - ENSMUSP00000143551
Ensembl peptide - ENSMUSP00000143458
Ensembl peptide - ENSMUSP00000143452
Ensembl peptide - ENSMUSP00000143258
Ensembl peptide - ENSMUSP00000087396
Ensembl peptide - ENSMUSP00000129481
Ensembl peptide - ENSMUSP00000142402
Ensembl peptide - ENSMUSP00000142682
NCBI entrez gene - 19352     See in Manteia.
MGI - MGI:99537
RefSeq - NM_001163478
RefSeq - NM_001163479
RefSeq - NM_011231
RefSeq Peptide - NP_001156951
RefSeq Peptide - NP_035361
RefSeq Peptide - NP_001156950
swissprot - Q3TVF4
swissprot - Q6PFA1
swissprot - A0A0G2JGU4
swissprot - Q9JIF6
swissprot - A0A0G2JGH5
swissprot - A0A0G2JG79
swissprot - A0A0G2JFP7
swissprot - A0A0G2JF29
swissprot - A0A0G2JDK3
swissprot - P53612
Ensembl - ENSMUSG00000038975
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rabggtbENSDARG00000068587Danio rerio
 RABGGTBENSGALG00000011388Gallus gallus
 P53611ENSG00000137955Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pggt1b / Q8BUY9 / Geranylgeranyl transferase type-1 subunit beta / P53609* / protein geranylgeranyltransferase type I subunit beta*ENSMUSG0000002447728


Protein motifs (from Interpro)
Interpro ID Name
 IPR001330  PFTB repeat
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR026873  Geranylgeranyl transferase type-2 subunit beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018344 protein geranylgeranylation IEA
 cellular_componentGO:0005968 Rab-protein geranylgeranyltransferase complex IBA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004659 prenyltransferase activity IEA
 molecular_functionGO:0004663 Rab geranylgeranyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017137 Rab GTPase binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
RAB geranylgeranylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / complex / reaction
 ENSMUSG00000040472 Q9JHK4 / Rabggta / Geranylgeranyl transferase type-2 subunit alpha / Q92696* / Rab geranylgeranyltransferase alpha subunit*  / reaction / complex
 ENSMUSG00000028788 O70274 / Ptp4a2 / Protein tyrosine phosphatase type IVA 2 / Q12974* / protein tyrosine phosphatase type IVA, member 2*  / reaction / complex
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / reaction / complex






 

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