ENSMUSG00000039194


Mus musculus

Features
Gene ID: ENSMUSG00000039194
  
Biological name :Rlbp1
  
Synonyms : Q9Z275 / retinaldehyde binding protein 1 / Rlbp1
  
Possible biological names infered from orthology : P12271
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D2
Gene start: 79374870
Gene end: 79387048
  
Corresponding Affymetrix probe sets: 10564726 (MoGene1.0st)   1418310_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137143
Ensembl peptide - ENSMUSP00000146196
Ensembl peptide - ENSMUSP00000146144
Ensembl peptide - ENSMUSP00000146075
Ensembl peptide - ENSMUSP00000145850
Ensembl peptide - ENSMUSP00000145611
Ensembl peptide - ENSMUSP00000054545
NCBI entrez gene - 19771     See in Manteia.
MGI - MGI:97930
RefSeq - NM_001173483
RefSeq - XM_011250827
RefSeq - XM_006540718
RefSeq - XM_006540717
RefSeq - NM_020599
RefSeq Peptide - NP_001166954
RefSeq Peptide - NP_001344379
RefSeq Peptide - NP_065624
swissprot - A0A0U1RPQ2
swissprot - A0A0U1RPV9
swissprot - Q544Y3
swissprot - Q9Z275
swissprot - A0A0U1RP66
swissprot - A0A0U1RNL2
swissprot - A0A0U1RQ07
Ensembl - ENSMUSG00000039194
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rlbp1aENSDARG00000012504Danio rerio
 rlbp1bENSDARG00000045808Danio rerio
 RLBP1ENSGALG00000006676Gallus gallus
 RLBP1ENSG00000140522Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clvs1 / Q9D4C9 / Clavesin-1 / Q8IUQ0*ENSMUSG0000004121635
Clvs2 / Q8BG92 / Clavesin-2 / Q5SYC1*ENSMUSG0000001978534
Ttpal / Q9D3D0 / tocopherol (alpha) transfer protein-like / Q9BTX7* / alpha tocopherol transfer protein like*ENSMUSG0000001767933
Ttpa / Q8BWP5 / tocopherol (alpha) transfer protein / P49638* / alpha tocopherol transfer protein*ENSMUSG0000007398826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001251  CRAL-TRIO lipid binding domain
 IPR011074  CRAL/TRIO, N-terminal domain
 IPR032941  Retinaldehyde-binding protein 1
 IPR036273  CRAL/TRIO, N-terminal domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0050896 response to stimulus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0044297 cell body IEA
 molecular_functionGO:0005502 11-cis retinal binding IDA
 molecular_functionGO:0016918 retinal binding IEA
 molecular_functionGO:0019841 retinol binding IEA


Pathways (from Reactome)
Pathway description
The retinoid cycle in cones (daylight vision)
The canonical retinoid cycle in rods (twilight vision)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001326 retinal degeneration "pathological change in the thin layer of neural tissue lining the back of the eyeball, which contains visual receptors and can result in the impairment or cessation of retinal neural function" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0001327 reduced retinal photoreceptor cell number "fewer than the expected number of rods and/or cones" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0003011 delayed dark adaptation "increase in time required for the eye to recover its sensitivity in the dark following exposure to bright lights" [J:68444, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0003345 decreased number of ribs "fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0003898 abnormal QRS complex "anomaly in the largest-amplitude portion of the ECG, caused by currents generated when the ventricles depolarise prior to their contraction" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Psphtm1.1(KOMP)Vlcg/Psphtm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Psphtm1.1(KOMP)Vlcg/Ucd

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025921 Rdh10 / Q8VCH7 / Retinol dehydrogenase 10 / Q8IZV5*  / reaction
 ENSMUSG00000025350 Rdh5 / O55240 / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA. / Q92781* / retinol dehydrogenase 5*  / reaction
 ENSMUSG00000031220 Awat2 / Q6E1M8 / Acyl-CoA wax alcohol acyltransferase 2 / Q6E213*  / reaction
 ENSMUSG00000066441 Rdh11 / Q9QYF1 / Retinol dehydrogenase 11 / Q8TC12* / retinol dehydrogenase 11 (all-trans/9-cis/11-cis)*  / reaction






 

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