ENSMUSG00000019785


Mus musculus

Features
Gene ID: ENSMUSG00000019785
  
Biological name :Clvs2
  
Synonyms : Clavesin-2 / Clvs2 / Q8BG92
  
Possible biological names infered from orthology : Q5SYC1
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B1
Gene start: 33512286
Gene end: 33624769
  
Corresponding Affymetrix probe sets: 10368598 (MoGene1.0st)   1437292_at (Mouse Genome 430 2.0 Array)   1443063_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151805
Ensembl peptide - ENSMUSP00000019920
Ensembl peptide - ENSMUSP00000125100
NCBI entrez gene - 215890     See in Manteia.
MGI - MGI:2443223
RefSeq - NM_175448
RefSeq - XM_006512693
RefSeq - XM_017313882
RefSeq Peptide - NP_780657
swissprot - A0A1W2P7U8
swissprot - Q8BG92
Ensembl - ENSMUSG00000019785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLVS2ENSGALG00000014853Gallus gallus
 CLVS2ENSG00000146352Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clvs1 / Q9D4C9 / Clavesin-1 / Q8IUQ0*ENSMUSG0000004121680
Rlbp1 / Q9Z275 / retinaldehyde binding protein 1 / P12271*ENSMUSG0000003919433
Ttpal / Q9D3D0 / tocopherol (alpha) transfer protein-like / Q9BTX7* / alpha tocopherol transfer protein like*ENSMUSG0000001767932
Ttpa / Q8BWP5 / tocopherol (alpha) transfer protein / P49638* / alpha tocopherol transfer protein*ENSMUSG0000007398827


Protein motifs (from Interpro)
Interpro ID Name
 IPR001251  CRAL-TRIO lipid binding domain
 IPR011074  CRAL/TRIO, N-terminal domain
 IPR028636  Clavesin-2
 IPR036273  CRAL/TRIO, N-terminal domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007040 lysosome organization ISS
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding ISS


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003309 Ap1m2 / adaptor related protein complex 1 mu 2 subunit / Q9Y6Q5*  / complex
 ENSMUSG00000009090 Ap1b1 / O35643 / Mus musculus adaptor protein complex AP-1, beta 1 subunit (Ap1b1), transcript variant 4, mRNA. / Q10567* / adaptor related protein complex 1 beta 1 subunit*  / complex
 ENSMUSG00000004849 Ap1s1 / P61967 / AP-1 complex subunit sigma-1A / P61966* / adaptor related protein complex 1 sigma 1 subunit*  / complex
 ENSMUSG00000031367 Ap1s2 / Q9DB50 / AP-1 complex subunit sigma-2 / P56377* / adaptor related protein complex 1 sigma 2 subunit*  / complex
 ENSMUSG00000031731 Ap1g1 / P22892 / AP-1 complex subunit gamma-1 / O43747* / adaptor related protein complex 1 gamma 1 subunit*  / complex
 ENSMUSG00000054702 Ap1s3 / Q7TN05 / AP-1 complex subunit sigma-3 / Q96PC3* / adaptor related protein complex 1 sigma 3 subunit*  / complex
 ENSMUSG00000003033 Ap1m1 / P35585 / AP-1 complex subunit mu-1 / Q9BXS5* / adaptor related protein complex 1 mu 1 subunit*  / complex






 

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