ENSG00000146352


Homo sapiens

Features
Gene ID: ENSG00000146352
  
Biological name :CLVS2
  
Synonyms : clavesin 2 / CLVS2 / Q5SYC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q22.31
Gene start: 122995971
Gene end: 123072927
  
Corresponding Affymetrix probe sets: 1562443_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000275162
Ensembl peptide - ENSP00000357423
NCBI entrez gene - 134829     See in Manteia.
OMIM - 616945
RefSeq - XM_017010266
RefSeq - NM_001010852
RefSeq Peptide - NP_001010852
swissprot - Q5SYC1
Ensembl - ENSG00000146352
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CLVS2ENSGALG00000014853Gallus gallus
 Clvs2ENSMUSG00000019785Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLVS1 / Q8IUQ0 / clavesin 1ENSG0000017718281
RLBP1 / P12271 / retinaldehyde binding protein 1ENSG0000014052233
TTPAL / Q9BTX7 / alpha tocopherol transfer protein likeENSG0000012412033
TTPA / P49638 / alpha tocopherol transfer proteinENSG0000013756127


Protein motifs (from Interpro)
Interpro ID Name
 IPR001251  CRAL-TRIO lipid binding domain
 IPR011074  CRAL/TRIO, N-terminal domain
 IPR028636  Clavesin-2
 IPR036273  CRAL/TRIO, N-terminal domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007040 lysosome organization ISS
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129354 AP1M2 / Q9Y6Q5 / adaptor related protein complex 1 mu 2 subunit  / complex
 ENSG00000072958 AP1M1 / Q9BXS5 / adaptor related protein complex 1 mu 1 subunit  / complex
 ENSG00000141367 CLTC / Q00610 / clathrin heavy chain  / complex
 ENSG00000166747 AP1G1 / O43747 / adaptor related protein complex 1 gamma 1 subunit  / complex
 ENSG00000152056 AP1S3 / Q96PC3 / adaptor related protein complex 1 sigma 3 subunit  / complex
 ENSG00000182287 AP1S2 / P56377 / adaptor related protein complex 1 sigma 2 subunit  / complex
 ENSG00000100280 AP1B1 / Q10567 / adaptor related protein complex 1 beta 1 subunit  / complex
 ENSG00000106367 AP1S1 / P61966 / adaptor related protein complex 1 sigma 1 subunit  / complex






 

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