ENSG00000177182


Homo sapiens

Features
Gene ID: ENSG00000177182
  
Biological name :CLVS1
  
Synonyms : clavesin 1 / CLVS1 / Q8IUQ0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q12.2
Gene start: 61057158
Gene end: 61501645
  
Corresponding Affymetrix probe sets: 230217_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428402
Ensembl peptide - ENSP00000429869
Ensembl peptide - ENSP00000429544
Ensembl peptide - ENSP00000429244
Ensembl peptide - ENSP00000428986
Ensembl peptide - ENSP00000325506
Ensembl peptide - ENSP00000428174
NCBI entrez gene - 157807     See in Manteia.
OMIM - 611292
RefSeq - XM_017013142
RefSeq - NM_173519
RefSeq - XM_017013141
RefSeq Peptide - NP_775790
swissprot - G3V122
swissprot - E5RK22
swissprot - Q8IUQ0
swissprot - A0A1D5RMS6
swissprot - E5RI68
Ensembl - ENSG00000177182
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clvs2ENSDARG00000053122Danio rerio
 Clvs1ENSMUSG00000041216Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLVS2 / Q5SYC1 / clavesin 2ENSG0000014635275
RLBP1 / P12271 / retinaldehyde binding protein 1ENSG0000014052231
TTPAL / Q9BTX7 / alpha tocopherol transfer protein likeENSG0000012412031
TTPA / P49638 / alpha tocopherol transfer proteinENSG0000013756125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001251  CRAL-TRIO lipid binding domain
 IPR011074  CRAL/TRIO, N-terminal domain
 IPR028634  Clavesin-1
 IPR036273  CRAL/TRIO, N-terminal domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007040 lysosome organization IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0080025 phosphatidylinositol-3,5-bisphosphate binding IEA


Pathways (from Reactome)
Pathway description
Lysosome Vesicle Biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129354 AP1M2 / Q9Y6Q5 / adaptor related protein complex 1 mu 2 subunit  / complex
 ENSG00000072958 AP1M1 / Q9BXS5 / adaptor related protein complex 1 mu 1 subunit  / complex
 ENSG00000166747 AP1G1 / O43747 / adaptor related protein complex 1 gamma 1 subunit  / complex
 ENSG00000152056 AP1S3 / Q96PC3 / adaptor related protein complex 1 sigma 3 subunit  / complex
 ENSG00000182287 AP1S2 / P56377 / adaptor related protein complex 1 sigma 2 subunit  / complex
 ENSG00000100280 AP1B1 / Q10567 / adaptor related protein complex 1 beta 1 subunit  / complex
 ENSG00000141367 CLTC / Q00610 / clathrin heavy chain  / complex
 ENSG00000106367 AP1S1 / P61966 / adaptor related protein complex 1 sigma 1 subunit  / complex






 

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