ENSMUSG00000043342


Mus musculus

Features
Gene ID: ENSMUSG00000043342
  
Biological name :Hoxd9
  
Synonyms : Homeobox protein Hox-D9 / Hoxd9 / P28357
  
Possible biological names infered from orthology : homeobox D9 / P28356
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C3
Gene start: 74697727
Gene end: 74700208
  
Corresponding Affymetrix probe sets: 10472962 (MoGene1.0st)   1419126_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000058490
NCBI entrez gene - 15438     See in Manteia.
MGI - MGI:96210
RefSeq - NM_013555
RefSeq Peptide - NP_038583
swissprot - P28357
Ensembl - ENSMUSG00000043342
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HOXD9ENSGALG00000027513Gallus gallus
 HOXD9ENSG00000128709Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hoxc9 / P09633 / Homeobox protein Hox-C9 / P31274* / homeobox C9*ENSMUSG0000003613940
Hoxa9 / P09631 / Homeobox protein Hox-A9 / P31269* / AC004080.3* / homeobox A9*ENSMUSG0000003822736
Hoxb9 / P20615 / Homeobox protein Hox-B9 / P17482* / homeobox B9*ENSMUSG0000002087535
Hoxa10 / P31310 / Homeobox protein Hox-A10 / P31260* / homeobox A10*ENSMUSG0000000093830
Hoxc10 / P31257 / Homeobox protein Hox-C10 / Q9NYD6* / homeobox C10*ENSMUSG0000002248426
Hoxd10 / P28359 / Homeobox protein Hox-D10 / P28358* / homeobox D10*ENSMUSG0000005036824
Hoxd11 / homeobox D11 / P31277*ENSMUSG0000004249922
Hoxa11 / P31311 / Homeobox protein Hox-A11 / P31270* / homeobox A11*ENSMUSG0000003821020
Hoxc11 / P31313 / Homeobox protein Hox-C11 / O43248* / homeobox C11*ENSMUSG0000000165620
Hoxc12 / Q8K5B8 / Homeobox protein Hox-C12 / P31275* / homeobox C12*ENSMUSG0000005032819
Hoxd12 / P23812 / Homeobox protein Hox-D12 / P35452* / homeobox D12*ENSMUSG0000000182319
Hoxa13 / homeobox protein Hox-A13 / P31271* / homeobox A13*ENSMUSG0000003820317
Hoxc13 / P50207 / Homeobox protein Hox-C13 / P31276* / homeobox C13*ENSMUSG0000000165516
Hoxb13 / P70321 / Homeobox protein Hox-B13 / Q92826* / homeobox B13*ENSMUSG0000004960415
Hoxd13 / P70217 / Homeobox protein Hox-D13 / P35453* / homeobox D13*ENSMUSG0000000181915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006711  Hox9, N-terminal activation domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007338 single fertilization IGI
 biological_processGO:0007519 skeletal muscle tissue development IGI
 biological_processGO:0008344 adult locomotory behavior IGI
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0009954 proximal/distal pattern formation IMP
 biological_processGO:0010468 regulation of gene expression IGI
 biological_processGO:0030879 mammary gland development IGI
 biological_processGO:0035115 embryonic forelimb morphogenesis IMP
 biological_processGO:0035136 forelimb morphogenesis IGI
 biological_processGO:0035137 hindlimb morphogenesis IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0048704 embryonic skeletal system morphogenesis IGI
 biological_processGO:0048706 embryonic skeletal system development IMP
 biological_processGO:0048935 peripheral nervous system neuron development IGI
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000154 rib fusion "appearance of one or more ribs as a single structure" [J:62022, J:62023]
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Allelic Composition: Hoxa6tm1Mrc/Hoxa6tm1Mrc,Hoxb6tm1Mrc/Hoxb6tm1Mrc,Hoxc6tm1Dds/Hoxc6tm1Dds
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0000550 abnormal forelimb morphology "malformation of the entire anterior extremities" [MGI:tc]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000556 abnormal hindlimb morphology "malformation of the entire posterior extremities" [MGI:tc]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Cdh2Gt(OST49160)Lex/Cdh2Gt(OST49160)Lex
Genetic Background: involves: 129S5/SvEvBrd

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001077 abnormal spinal nerve morphology "any anomaly, deformity, or malformation of the any of the 31 paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001388 abnormal stationary movement "altered ability or inability to change body posture or shift a body part" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Il4ratm1Sz/Il4ratm1Sz
Genetic Background: BALB/c-Il4ratm1Sz

 MP:0001392 abnormal locomotor activity "altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Il4ratm1Sz/Il4ratm1Sz
Genetic Background: BALB/c-Il4ratm1Sz

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001407 short stride length "reduced average distance between steps" [J:34193]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001882 abnormal lactation "atypical production of milk from the mammary gland" [J:51296]
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Allelic Composition: Cdh2Gt(OST49160)Lex/Cdh2Gt(OST49160)Lex
Genetic Background: involves: 129S5/SvEvBrd

Allelic Composition: Hoxa9tm1Mrc/Hoxa9+,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: Not Specified

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Hoxa9tm1Ipc/Hoxa9+
Genetic Background: either: 129/Sv-Hoxa9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Hoxa9tm1Ipc/Hoxa9+
Genetic Background: either: 129/Sv-Hoxa9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa9tm1Ipc/Hoxa9+
Genetic Background: either: 129/Sv-Hoxa9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

 MP:0002651 abnormal sciatic nerve "malformation, absence or misprojection of the nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002823 abnormal rib development "anomalous formation of the bones forming the bony wall of the chest" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84754]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002932 abnormal joint "defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003036 vertebral transformation "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003049 abnormal lumbar vertebrae morphology "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003050 abnormal sacral vertebrae morphology "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003344 mammary gland hypoplasia "decreased size of mammary gland due to decreased cell number" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Cdh2Gt(OST49160)Lex/Cdh2Gt(OST49160)Lex
Genetic Background: involves: 129S5/SvEvBrd

Allelic Composition: Hoxa9tm1Mrc/Hoxa9+,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: Not Specified

 MP:0004322 abnormal sternebra morphology "any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0004353 abnormal deltoid tuberosity morphology "any structural anomaly of a rough elevation at the middle of the lateral side of the shaft of the humerus to which the deltoid muscle attaches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0004614 caudal vertebral transformation "homeotic transformation of any caudal vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0004616 lumbar vertebral transformation "homeotic transformation of any lumbar vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxd9tm1Ipc/Hoxd9+
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9+
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004617 sacral vertebral transformation "homeotic transformation of any sacral vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004622 sacral vertebral fusion "the union of one or more sacral vertebrae into a single structure in species where this does not normally occur" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxd9tm1Ipc/Hoxd9+
Genetic Background: either: 129/Sv-Hoxd9tm1Ipc or (involves: 129/Sv * 129S2/SvPas * C57BL/6)

 MP:0004625 abnormal rib attachment "any anomaly in the in the normal joining of the ribs to the vertebral column or to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004703 abnormal vertebral column "any structural anomaly of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9+,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9+
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0005296 abnormal humerus morphology "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Hoxa9tm1Ipc/Hoxa9tm1Ipc,Hoxd9tm1Ipc/Hoxd9tm1Ipc
Genetic Background: involves: 129/Sv * 129S2/SvPas * C57BL/6

 MP:0005353 abnormal patella morphology "anomalous structure of the large sesamoid bone that covers the anterior surface of the knee" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005503 abnormal tendon morphology "structural anomaly of the fibrous bands or cords of connective tissue at the ends of muscle fibers that attach muscles to bones and other structures" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:45509]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008028 pregnancy-related premature death "death occuring before the normal life span of an organism, occuring during pregnancy, parturition or lactation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009005 abnormal sesamoid bone of gastrocnemius morphology "any structural anomaly of the small sesamoid bones situated behind the condyles of the femur" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009450 abnormal axon fasiculation "anomaly in the process by which axons form into bundles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxd9tm1Emca/Hoxd9tm1Emca,Hoxd10tm1Emca/Hoxd10tm1Emca
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0010103 small thoracic cage "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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