MP:0000137 | abnormal vertebrae morphology | "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000464 | increased number of presacral vertebrae | "greater number of the vertebrae anterior to the sacrum" [J:13069] |
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Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
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MP:0000520 | absent kidney | "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000521 | abnormal kidney cortex | "anomalous structure or development of the outer area of the kidney, which contains the glomerular capillaries and the capsula glomeruli that enclose it " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000524 | reduced renal tubule number | "fewer loops of Henle and collecting ducts" [J:40203] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0000552 | abnormal radius morphology | "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
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MP:0000553 | absent radius | "missing the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000554 | abnormal carpal bone morphology | "malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0000555 | absent carpal bone | "missing the wrist bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0001539 | decreased number of caudal vertebrae | "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0002110 | abnormal digit morphology | "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: involves: 129S2/SvPas * C57BL/6J
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MP:0002115 | abnormal skeleton extremities morphology | "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
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MP:0002160 | abnormal reproductive system morphology | "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0002187 | abnormal fibula morphology | "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0002703 | abnormal renal tubules | "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0002705 | dilated renal tubules | "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0002769 | abnormal vas deferens morphology | "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0003049 | abnormal lumbar vertebrae morphology | "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Xisttm2Nbd/Xist+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm2Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
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MP:0003050 | abnormal sacral vertebrae morphology | "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0003446 | renal hypoplasia | "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: Not Specified
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0003600 | ectopic kidney | |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0003604 | single kidney | |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: Not Specified
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0003613 | abnormal kidney medulla development | |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0003626 | kidney medulla hypoplasia | |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0003672 | abnormal ureter development | "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0003723 | abnormal long bone morphology | "malformation of any of the several elongated bones of the extremities
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0003855 | abnormal forelimb zeugopod morphology | |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0003857 | abnormal hindlimb zeugopod morphology | |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004355 | short radius | "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004359 | short ulna | "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004360 | absent ulna | "missing the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0004509 | abnormal pelvic girdle bone morphology | "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004617 | sacral vertebral transformation | "homeotic transformation of any sacral vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: mixed
Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: Not Specified
Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004618 | thoracic vertebral transformation | "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0004634 | short metacarpal bones | "reduced length of the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
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MP:0004638 | elongated metacarpal bones | "increased length of the five bones of the forepaws/hands that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: BALB/cJ
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MP:0004647 | decreased lumbar vertebrae number | "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
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MP:0004649 | decreased sacral vertebrae number | "reduced number of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0004650 | increased lumbar vertebrae number | "increased number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0004656 | absent sacral vertebrae | "absence of all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MESH:National Library of Medicine_Medical Subject Headings] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0004936 | abnormal ureteric bud branching morphogenesis | "partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0005104 | abnormal tarsus morphology | "malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0005108 | abnormal ulna morphology | "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
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MP:0005306 | abnormal phalanx morphology | "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: BALB/cJ
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MP:0005354 | abnormal ilium morphology | "structural anomaly of the broad, flaring portion of the hip bone, which is distinct at birth, but later fuses with the ischium and the pubis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316] |
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Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
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MP:0008159 | increased diameter of fibula | "increased width of the cross-sectional distance that extends from one lateral edge of the fibula, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0008161 | increased diameter of radius | "increased width of the cross-sectional distance that extends from one lateral edge of the radius, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0008163 | increased diameter of ulna | "increased width of the cross-sectional distance that extends from one lateral edge of the ulna, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+ Genetic Background: involves: BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0008915 | fused carpal bones | "anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: mixed
Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: Not Specified
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0009728 | abnormal calcaneum morphology | "any structural anomaly of the largest quadrangular bone at the back of the tarsus; it forms the heel or hock and articulates with the talus above it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0010978 | absent ureteric bud | "absence of the epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme" [PMID:19828308] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0010983 | abnormal ureteric bud invasion | "any anomaly in the process in which the ureteric bud grows into the metanephric mesenchyme, and contributes to the formation of the metanephros" [PMID:19828308] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0010984 | abnormal metanephric mesenchyme morphology | "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)
Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd
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MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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MP:0011366 | absent metanephros | "absence of the primordium of the permanent kidney, which develops later than and caudal to the mesonephros, from the mesonephric duct and nephrogenic cord" [MGI:anna] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0011386 | increased metanephric mesenchyme apoptosis | "increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion" [MGI:anna] |
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc Genetic Background: involves: 129S7/SvEvBrd
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MP:0011565 | kidney papillary hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the apex of the renal pyramid that normally projects into a calyx" [MGI:anna] |
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa Genetic Background: involves: 129S7/SvEvBrd
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