ENSMUSG00000042499


Mus musculus

Features
Gene ID: ENSMUSG00000042499
  
Biological name :Hoxd11
  
Synonyms : homeobox D11 / Hoxd11
  
Possible biological names infered from orthology : P31277
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C3
Gene start: 74679557
Gene end: 74687016
  
Corresponding Affymetrix probe sets: 10472953 (MoGene1.0st)   1450584_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122582
NCBI entrez gene - 15431     See in Manteia.
MGI - MGI:96203
RefSeq - NM_008273
RefSeq Peptide - NP_032299
swissprot - A2ASM7
Ensembl - ENSMUSG00000042499
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q90470ENSDARG00000059267Danio rerio
 HOXD11ENSGALG00000039629Gallus gallus
 HOXD11ENSG00000128713Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hoxa11 / P31311 / Homeobox protein Hox-A11 / P31270* / homeobox A11*ENSMUSG0000003821050
Hoxc11 / P31313 / Homeobox protein Hox-C11 / O43248* / homeobox C11*ENSMUSG0000000165643
Hoxa10 / P31310 / Homeobox protein Hox-A10 / P31260* / homeobox A10*ENSMUSG0000000093824
Hoxa9 / P09631 / Homeobox protein Hox-A9 / P31269* / AC004080.3* / homeobox A9*ENSMUSG0000003822722
Hoxd9 / P28357 / Homeobox protein Hox-D9 / P28356* / homeobox D9*ENSMUSG0000004334222
Hoxd10 / P28359 / Homeobox protein Hox-D10 / P28358* / homeobox D10*ENSMUSG0000005036821
Hoxb9 / P20615 / Homeobox protein Hox-B9 / P17482* / homeobox B9*ENSMUSG0000002087521
Hoxc10 / P31257 / Homeobox protein Hox-C10 / Q9NYD6* / homeobox C10*ENSMUSG0000002248421
Hoxc9 / P09633 / Homeobox protein Hox-C9 / P31274* / homeobox C9*ENSMUSG0000003613920
Hoxd12 / P23812 / Homeobox protein Hox-D12 / P35452* / homeobox D12*ENSMUSG0000000182320
Hoxa13 / homeobox protein Hox-A13 / P31271* / homeobox A13*ENSMUSG0000003820319
Hoxb13 / P70321 / Homeobox protein Hox-B13 / Q92826* / homeobox B13*ENSMUSG0000004960418
Hoxc13 / P50207 / Homeobox protein Hox-C13 / P31276* / homeobox C13*ENSMUSG0000000165518
Hoxc12 / Q8K5B8 / Homeobox protein Hox-C12 / P31275* / homeobox C12*ENSMUSG0000005032818
Hoxd13 / P70217 / Homeobox protein Hox-D13 / P35453* / homeobox D13*ENSMUSG0000000181917


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa
 IPR021918  Domain of unknown function DUF3528, homeobox protein, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000464 increased number of presacral vertebrae "greater number of the vertebrae anterior to the sacrum" [J:13069]
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Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

 MP:0000520 absent kidney "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000521 abnormal kidney cortex "anomalous structure or development of the outer area of the kidney, which contains the glomerular capillaries and the capsula glomeruli that enclose it " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000524 reduced renal tubule number "fewer loops of Henle and collecting ducts" [J:40203]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000552 abnormal radius morphology "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

 MP:0000553 absent radius "missing the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000554 abnormal carpal bone morphology "malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0000555 absent carpal bone "missing the wrist bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54637]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000572 abnormal autopod morphology "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002115 abnormal skeleton extremities morphology "abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

 MP:0002160 abnormal reproductive system morphology "structural or developmental anomaly of any of the tissues involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa11tm1Dmwe/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002187 abnormal fibula morphology "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0002703 abnormal renal tubules "anomalous structure or development of the loops of Henle and collecting ducts in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002705 dilated renal tubules "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002769 abnormal vas deferens morphology "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003049 abnormal lumbar vertebrae morphology "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Xisttm2Nbd/Xist+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm2Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003050 abnormal sacral vertebrae morphology "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0003446 renal hypoplasia "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003600 ectopic kidney 
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003604 single kidney 
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003613 abnormal kidney medulla development 
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003626 kidney medulla hypoplasia 
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0003672 abnormal ureter development "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003675 kidney cysts "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0003723 abnormal long bone morphology "malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003855 abnormal forelimb zeugopod morphology 
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0003857 abnormal hindlimb zeugopod morphology 
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004360 absent ulna "missing the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004509 abnormal pelvic girdle bone morphology "any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004617 sacral vertebral transformation "homeotic transformation of any sacral vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: mixed

Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004634 short metacarpal bones "reduced length of the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

 MP:0004638 elongated metacarpal bones "increased length of the five bones of the forepaws/hands that articulate proximally with the carpal bones and distally with the phalanges" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: BALB/cJ

 MP:0004647 decreased lumbar vertebrae number "reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

 MP:0004649 decreased sacral vertebrae number "reduced number of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004650 increased lumbar vertebrae number "increased number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm2Ddu/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm2.1Ddu/Hoxd11+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm2Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004656 absent sacral vertebrae "absence of all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0004936 abnormal ureteric bud branching morphogenesis "partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005104 abnormal tarsus morphology "malformation or absence of any of the eight bones of the instep of the paw: tibiale, talus, calcaneus, navicular, 3 cuneiform, and cuboid bones" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0005108 abnormal ulna morphology "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

 MP:0005306 abnormal phalanx morphology "aberrant structure of any of the long bones of the digits" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: BALB/cJ

 MP:0005354 abnormal ilium morphology "structural anomaly of the broad, flaring portion of the hip bone, which is distinct at birth, but later fuses with the ischium and the pubis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316]
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Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

 MP:0008159 increased diameter of fibula "increased width of the cross-sectional distance that extends from one lateral edge of the fibula, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008161 increased diameter of radius "increased width of the cross-sectional distance that extends from one lateral edge of the radius, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008163 increased diameter of ulna "increased width of the cross-sectional distance that extends from one lateral edge of the ulna, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm2.1(Hoxd11)Mrc/Hoxd11+
Genetic Background: involves: BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008770 decreased survivor rate "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0008915 fused carpal bones "anomaly of the nine nodular bones of the joint between the forelimb bones and the front paws/hands resulting in some or all the bones being joined together" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11+,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: mixed

Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm2.1Ddu/Hoxd11tm2.1Ddu
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Del(2Hoxd11-Hoxd13)29Ddu/Del(2Hoxd11-Hoxd13)29Ddu,Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Hoxd11tm1Ipc/Hoxd11tm1Ipc
Genetic Background: either: (involves: 129/Sv * 129S2/SvPas) or (involves: 129S2/SvPas * C57BL/6)

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm2.1(Hoxd11)Mrc
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0009728 abnormal calcaneum morphology "any structural anomaly of the largest quadrangular bone at the back of the tarsus; it forms the heel or hock and articulates with the talus above it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0010978 absent ureteric bud "absence of the epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme" [PMID:19828308]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0010983 abnormal ureteric bud invasion "any anomaly in the process in which the ureteric bud grows into the metanephric mesenchyme, and contributes to the formation of the metanephros" [PMID:19828308]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11+,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11+,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0010984 abnormal metanephric mesenchyme morphology "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm2.1(Hoxa13)Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: either: (involves: 129P2/OlaHsd * 129S2/SvPas * 129S7/SvEvBrd) or (involves: 129S1/Sv * 129S2/SvPas * 129S7/SvEvBrd * 129X1/SvJ)

Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Hoxa11tm1Ssp/Hoxa11tm1Ssp,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0011090 partial perinatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011366 absent metanephros "absence of the primordium of the permanent kidney, which develops later than and caudal to the mesonephros, from the mesonephric duct and nephrogenic cord" [MGI:anna]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011386 increased metanephric mesenchyme apoptosis "increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion" [MGI:anna]
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Allelic Composition: Hoxa11tm1Mrc/Hoxa11tm1Mrc,Hoxc11tm1Mrc/Hoxc11tm1Mrc,Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0011565 kidney papillary hypoplasia "underdevelopment or reduced size, usually due to a reduced number of cells, of the apex of the renal pyramid that normally projects into a calyx" [MGI:anna]
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Allelic Composition: Ednratm1Ywa/Ednratm1Ywa
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
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