ENSMUSG00000036139


Mus musculus

Features
Gene ID: ENSMUSG00000036139
  
Biological name :Hoxc9
  
Synonyms : Homeobox protein Hox-C9 / Hoxc9 / P09633
  
Possible biological names infered from orthology : homeobox C9 / P31274
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: F3
Gene start: 102976439
Gene end: 102985099
  
Corresponding Affymetrix probe sets: 10427286 (MoGene1.0st)   1449867_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001706
Ensembl peptide - ENSMUSP00000134197
NCBI entrez gene - 15427     See in Manteia.
MGI - MGI:96199
RefSeq - NM_008272
RefSeq Peptide - NP_032298
swissprot - P09633
Ensembl - ENSMUSG00000036139
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hoxc9aENSDARG00000092809Danio rerio
 HOXC9ENSGALG00000029439Gallus gallus
 HOXC9ENSG00000180806Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Hoxd9 / P28357 / Homeobox protein Hox-D9 / P28356* / homeobox D9*ENSMUSG0000004334252
Hoxb9 / P20615 / Homeobox protein Hox-B9 / P17482* / homeobox B9*ENSMUSG0000002087550
Hoxa9 / P09631 / Homeobox protein Hox-A9 / P31269* / AC004080.3* / homeobox A9*ENSMUSG0000003822748
Hoxa10 / P31310 / Homeobox protein Hox-A10 / P31260* / homeobox A10*ENSMUSG0000000093837
Hoxd10 / P28359 / Homeobox protein Hox-D10 / P28358* / homeobox D10*ENSMUSG0000005036832
Hoxc10 / P31257 / Homeobox protein Hox-C10 / Q9NYD6* / homeobox C10*ENSMUSG0000002248431
Hoxc12 / Q8K5B8 / Homeobox protein Hox-C12 / P31275* / homeobox C12*ENSMUSG0000005032826
Hoxa11 / P31311 / Homeobox protein Hox-A11 / P31270* / homeobox A11*ENSMUSG0000003821026
Hoxd11 / homeobox D11 / P31277*ENSMUSG0000004249926
Hoxc11 / P31313 / Homeobox protein Hox-C11 / O43248* / homeobox C11*ENSMUSG0000000165624
Hoxd12 / P23812 / Homeobox protein Hox-D12 / P35452* / homeobox D12*ENSMUSG0000000182323
Hoxa13 / homeobox protein Hox-A13 / P31271* / homeobox A13*ENSMUSG0000003820322
Hoxb13 / P70321 / Homeobox protein Hox-B13 / Q92826* / homeobox B13*ENSMUSG0000004960421
Hoxd13 / P70217 / Homeobox protein Hox-D13 / P35453* / homeobox D13*ENSMUSG0000000181921
Hoxc13 / P50207 / Homeobox protein Hox-C13 / P31276* / homeobox C13*ENSMUSG0000000165520


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006711  Hox9, N-terminal activation domain
 IPR009057  Homeobox-like domain superfamily
 IPR017112  Homeobox protein HXA9/HXB9/HXC9
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0048704 embryonic skeletal system morphogenesis IMP
 biological_processGO:0048706 embryonic skeletal system development IGI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0016235 aggresome IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000154 rib fusion "appearance of one or more ribs as a single structure" [J:62022, J:62023]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000157 abnormal sternum morphology "malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000159 abnormal xiphoid process "malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0002823 abnormal rib development "anomalous formation of the bones forming the bony wall of the chest" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:84754]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003036 vertebral transformation "homeotic transformation of a specific vertebrae to adopt the fate of another" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0003050 abnormal sacral vertebrae morphology "malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004322 abnormal sternebra morphology "any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004616 lumbar vertebral transformation "homeotic transformation of any lumbar vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004618 thoracic vertebral transformation "homeotic transformation of any thoracic vertebrae to adopt the fate of another vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0004625 abnormal rib attachment "any anomaly in the in the normal joining of the ribs to the vertebral column or to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9+,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0008146 asymmetric rib-sternum attachment "loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0008148 abnormal rib-sternum attachment "any anomaly in the in the normal joining of the ribs to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nf2tm2.1Gth/Nf2tm2.1Gth
Genetic Background: involves: 129P2/OlaHsd * FVB/N

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

 MP:0010103 small thoracic cage "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hoxa9tm1Mrc/Hoxa9tm1Mrc,Hoxb9tm1Mrc/Hoxb9tm1Mrc,Hoxc9tm1Mrc/Hoxc9tm1Mrc,Hoxd9tm1Mrc/Hoxd9tm1Mrc
Genetic Background: involves: 129S7/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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