Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000060	delayed bone ossification	"late onset of the formation of bone" [J:40203]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000220	increased monocyte count	"greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her
MP:0000351	increased cell proliferation	"greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1^{tm1(Wnt1)Wrst} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000550	abnormal forelimb morphology	"malformation of the entire anterior extremities" [MGI:tc]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000562	polydactyly	"greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj
MP:0000564	syndactyly	"any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj
MP:0000565	oligodactyly	"congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000567	truncation of digits	"absence of the most proximal regions of toes" [J:19212]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000568	ectopic digits	"positional abnormality of a digit" [J:50311]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000569	abnormal digit pigmentation	"anomalous coloration of the fingers or toes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^{tm3.1(En2)Alj}/En1^{tm3.1(En2)Alj} Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
MP:0000572	abnormal autopod morphology	"malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000574	abnormal foot pad morphology	"anomalous structure of the body of fat on the foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000579	abnormal nail morphology	"structural or developmental anomaly of any of the thin, horny, translucent plates covering the dorsal surface of the distal end of each terminal phalanx of the digits" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000580	deformed nails	"atypical shape or size of the nails" [J:45400]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^{tm3.1(En2)Alj}/En1^{tm3.1(En2)Alj} Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)
MP:0000675	abnormal palmar eccrine gland morphology	"malformation or absence of the sweat glands of the palm" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0000776	abnormal inferior colliculus	"dysmorphology or disorganization of the paired inferior eminence of the mesencephalic tectum that is involved in preliminary visual processing, and control of eye movements" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Lama2^dy-2J/Lama2^dy-2J Genetic Background: involves: WK/ReJ
MP:0000777	increased size of inferior colliculus	"enlargement of the paired inferior eminence of the mesencephalic tectum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57538]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1^{tm1(Wnt1)Wrst} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^{tm1.1(Wnt1)Wrst}/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0000820	abnormal choroid plexus morphology	"malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000836	abnormal substantia nigra morphology	"malformation or absence of the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis)" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0000841	abnormal hindbrain morphology	"malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1^{tm1(Wnt1)Wrst} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N
MP:0000849	abnormal cerebellum morphology	"any malformation or absence of the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement and learning of motor skills" [J:50311, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli1^tm2Alj/Gli1^tm2Alj,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/En1⁺,En2^tm2Alj/En2^tm2Alj,Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000850	absent cerebellum	"missing the part of the metencephalon that lies in the posterior cranial fossa dorsal to the pons and medulla that is concerned with the coordination of movement" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm1Alj/En1^tm1Alj,En2^tm1Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0000852	small cerebellum	"reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Lhx1^tm1Tmj/Lhx1^tm2.1Bhr,Lhx5^tm1Lmgd/Lhx5^tm1Lmgd Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0000854	abnormal cerebellum development	"malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^{tm1(PDGFB)Nist}/En1⁺ Genetic Background: involves: 129/Sv * C57BL/6 Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli1^tm2Alj/Gli1^tm2Alj,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm1Alj,Moen1^C57BL/6/Moen1^C57BL/6 Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: En1^tm1Alj/En1^tm1Alj,Moen2^C57BL/6/Moen2^C57BL/6 Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: En1^tm1Alj/En1^tm1Alj,Moen3^C57BL/6/Moen3^C57BL/6 Genetic Background: involves: 129S1/Sv * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000857	abnormal cerebellar foliation	"malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli1^tm2Alj/Gli1^tm2Alj,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm8.1Alj/En1⁺,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0000864	abnormal vermis	"malformation in the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/En1⁺,En2^tm2Alj/En2^tm2Alj,Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000865	absent vermis	"missing narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0000866	vermis hypoplasia	"reduced cell number in the vermis" [J:61509]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000867	abnormal anterior vermis	"malformation in the anterior portion of the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0000868	decreased size of anterior vermis	"smaller appearance of the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57538]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0000869	abnormal posterior vermis	"malformation in the posterior portion of the narrow middle zone between the two hemispheres of the cerebellum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61509]	Show Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm8.1Alj/En1⁺,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000872	abnormal external granule cell layer	"malformation of the transient layer of the cerebellar cortex which is composed of the dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000873	thin external granule cell layer	"reduced thickness of the transient layer of the cerebellar cortex which is composed of dividing and migrating granule cells" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0000875	abnormal cerebellar Purkinje cell layer	"any malformation or absence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex; it contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer, and candelabrum interneurons are vertically oriented between the Purkinje cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0000876	Purkinje cell degeneration	"a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0000877	abnormal Purkinje cell	"any structural anomaly of the neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex; these inhibitory neurons provide the output of the cerebellar cortex through axons that project into the white matter, and extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells" [J:46140, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0000880	decreased Purkinje cell number	"fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Lhx1^tm2.1Bhr/Lhx1^tm2.1Bhr Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0000886	abnormal cerebellar granule layer	"any malformation or absence of the innermost cortical layer of the cerebellum; contains densly packed small neurons, mostly granule cells with some Golgi cells are found at the outer border" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0000889	abnormal cerebellar molecular layer	"any malformation or absence of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0000897	abnormal midbrain	"malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6N Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N
MP:0000899	abnormal colliculi	"malformed inferior and superior colliculus" [J:50311]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0000905	increased size of superior colliculus	"enlargement of the paired superior eminence of the mesencephalic tectum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57538]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0000913	abnormal brain development	"malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0000933	abnormal rhombomere morphology	"malformation of the transverse segments in the hindbrain region of the developing neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]	Show Allelic Composition: Fgf8^tm1.4Mrt/Fgf8⁺,Gli3^tm1.1Alj/Gli3^tm1.1Alj Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gt(ROSA)26Sor^{tm5(CAG-EGFP,-lacZ)Dym}/?,Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr,Tg(Fev-flpe)1Dym/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N
MP:0001056	abnormal cranial nerve morphology	"any anomaly, deformity, or malformation of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0001062	absent oculomotor nerve	"missing nerve of the extraocular muscles, iris and ciliary body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0001063	abnormal trochlear nerve morphology	"any malformation or misprojection of the 4th cranial nerve, which normally carries the motor innervation of the superior oblique muscles of the eye " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0001064	absent trochlear nerve	"missing nerve of the superior oblique muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0001071	abnormal facial nerve morphology	"malformed or misprojection of motor axons from the pons to the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0001211	wrinkled skin	"irregular folds and/or indentations on the skin" [J:19212]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J
MP:0001263	weight loss	"progressive reduction of body weight below normal average for age" [J:45400]	Show Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0001364	decreased anxiety-related response	"when compared to controls, subjects exhibit fewer responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:86626, J:85438, J:64043]	Show Allelic Composition: Gt(ROSA)26Sor^{tm7(CAG-mCherry,-EGFP/tetX)Dym}/Gt(ROSA)26Sor⁺,Tmem163^{Tg(ACTB-cre)2Mrt}/0,Tg(Fev-flpe)1Dym/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0001392	abnormal locomotor activity	"altered ability or inability to move from place to place" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0001393	ataxia	"inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Gadd45b^tm1Flv/Gadd45b^tm1Flv,Gadd45g^tm1Flv/Gadd45g^tm1Flv Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Gld/En1^tm1Gld,Tg(Wnt1-En1)1Amc/0 Genetic Background: involves: 129S/SvEv Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0001436	abnormal suckling behavior	"reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0001438	aphagia	"inability to eat " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30404]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0001504	abnormal posture	"atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]	Show Allelic Composition: Cxcl13^tm1Cys/Cxcl13^tm1Cys Genetic Background: B6.129X1-Cxcl13^tm1Cys
MP:0001513	limb grasping	"mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Tg(Nes-cre)1Kln/0,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0001523	impaired righting response	"reduced ability or greater amount of time needed to recover from supine position" [J:25565]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0001524	impaired limb coordination	"reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0001525	impaired balance	"reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0001676	abnormal apical ectodermal ridge	"malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Allelic Composition: En1^tm1Alj/En1^tm1Alj,Rfng^tm1Tfv/Rfng^tm1Tfv Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm1Alj/En1^tm1Alj,Rfng^tm1Tfv/Rfng⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0001679	thin apical ectodermal ridge	"decrease in the thickness of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0001731	abnormal postnatal growth	"anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]	Show Allelic Composition: Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * SJL
MP:0001905	abnormal dopamine level	"greater or less than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0001906	increased dopamine level	"greater than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002058	neonatal lethality	"death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0002081	perinatal lethality	"death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Prnp^tm2Lnq/Prnp^tm2Lnq Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0002109	abnormal limb morphology	"abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * C57BL/6
MP:0002110	abnormal digit morphology	"abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^tm1Alj/En1^tm1Alj,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0002114	abnormal axial skeleton morphology	"abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0002115	abnormal skeleton extremities morphology	"abnormal development of limb, foot or tail bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002151	abnormal neural tube morphology/development	"anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Aicda^tm1Hon/Aicda^tm1Hon,Ighm^{tm1.1(IGH-2)Cog}/Ighm⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N
MP:0002152	abnormal brain morphology	"anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0002161	abnormal fertility/fecundity	"reduced ability or inability to produce live offspring" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm3(En2)Alj/En1^tm3(En2)Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Lhx1^tm2.1Bhr/Lhx1^tm2.1Bhr Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ Allelic Composition: En1^tm2(cre)Wrst/?,Gt(ROSA)26Sor^{tm5(CAG-EGFP,-lacZ)Dym}/?,Tg(Fev-flpe)1Dym/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0002183	gliosis	"increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0002184	abnormal innervation	"the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N
MP:0002199	abnormal brain commissure morphology	"absent or defective structure in a bundle of nerve fibers connecting the two brain hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0002206	abnormal CNS synaptic transmission	"defect in the communication from a neuron to a target across a synapse in the central nervous system" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Sim1^{tm1.1(cre)Gld}/Sim1⁺,Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * SJL Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: En1^tm2(cre)Gld/En1⁺,Tg(CAG-Bgeo,-AlstR,-EGFP)192Gld/0 Genetic Background: involves: 129S1/Sv
MP:0002229	CNS neurodegeneration	"a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pink1^tm1Aub/Pink1^tm1Aub,Tg(Prnp-SNCAA53T)AAub/Tg(Prnp-SNCAA53T)AAub Genetic Background: involves: 129S/SvEv * FVB/N Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0002272	abnormal nervous system electrophysiology	"anomaly in the function of the nervous system as it relates to electrical phenomena" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0002574	increased vertical activity	"greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0002882	abnormal neuron	"anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0002892	reduced size of superior colliculus	"decreased size of the paired superior eminence of the mesencephalic tectum" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0002961	abnormal axon guidance	"defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: En1^tm1Gld/En1⁺,Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
MP:0003077	abnormal cell cycle	"failure to progress or abnormal progression through the stages of of the cell cycle" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91266]	Show Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003091	abnormal cell migration	"defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: En1^{tm1(PDGFB)Nist}/En1⁺ Genetic Background: involves: 129/Sv * C57BL/6
MP:0003203	increased neuron apoptosis	"increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0003224	neuron degeneration	"a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0003225	axonal dystrophy	"axon degeneration resulting from inadequate or faulty metabolism" [RGD:Rat Genome Database submission]	Show Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0003243	abnormal dopaminergic neuron morphology	"malformation or absence of the neurons that utilize dopamine as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her
MP:0003244	loss of dopaminergic neurons	"loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]	Show Allelic Composition: Gadd45b^tm1Flv/Gadd45b^tm1Flv,Gadd45g^tm1Flv/Gadd45g^tm1Flv Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6
MP:0003245	abnormal GABA neuron morphology	"malformation or absence of the neurons that utilize gamma-aminobutyric acid as a neurotransmitter " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: Sod2^{tm1(tetO-Sod2)Evbo}/Sod2⁺ Genetic Background: involves: 129S4/SvJae * C57BL/6
MP:0003312	abnormal locomotor coordination	"reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0003345	decreased number of ribs	"fewer than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0003354	astrocytosis	"a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0003651	abnormal axon outgrowth	"defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]	Show Allelic Composition: En1^tm1Gld/En1⁺,Ntn1^Gt(ST629)Byg/Ntn1^Gt(ST629)Byg Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
MP:0003661	abnormal locus ceruleus	"anomaly in a dense cluster of neurons within the dorsorostral pons; it is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic" [J:96328, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0003704	abnormal hair follicle development	"anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0003813	abnormal dermal papilla	"abnormalities in this specialized group of mesenchymal cells necessary for initiation of follicle development" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0003864	abnormal midbrain development	"anomaly in the formation of or the patterning of the part of the brainstem developing from the middle of the three primary cerebral vesicles of the embryo" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0003877	abnormal serotonergic neuron morphology	"malformation or absence of the neurons that secrete serotonin" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:54240]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gata2^tm1Msal/Gata2^tm1Msal Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0003990	decreased neurotransmitter release	"reduced secretion of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gadd45b^tm1Flv/Gadd45b^tm1Flv,Gadd45g^tm1Flv/Gadd45g^tm1Flv Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6
MP:0004096	abnormal midbrain-hindbrain boundary development	"anomaly in the formation of the midbrain-hindbrain domain, comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; an organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0004100	abnormal spinal cord interneuron morphology	"malformation or absence of neurons that exclusively interact with other neurons in the spinal cord" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gt(ROSA)26Sor^tm1(DTA)Riet/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv
MP:0004321	short sternum	"reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0004322	abnormal sternebra morphology	"any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0004861	abnormal Raphe nucleus morphology	"any structural anomaly of the subgroup of the reticular nuclei of the brain stem that are located in and along the median plane of the medulla oblongata, pons, and mesencephalon that include neurons that synthesize serotonin and extend ascending fibers to parts of the limbic system and descending fibers to other brain stem nuclei, the medulla oblongata, and the pons" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0004924	abnormal behavior	"anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Gadd45b^tm1Flv/Gadd45b^tm1Flv,Gadd45g^tm1Flv/Gadd45g^tm1Flv Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6
MP:0004950	abnormal brain vasculature	"any structural anomaly of the blood vessel network of the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^{tm1(PDGFB)Nist}/En1⁺ Genetic Background: involves: 129/Sv * C57BL/6
MP:0004981	decreased neuronal precursor cell number	"reduced number of the neuroblast embryonic cells that develop into nerve cells or neurons" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N
MP:0005322	abnormal serotonin level	"anomalous concentration of biochemical messenger and regulator, found in the CNS, g.i. tract, and produced by platelets; it mediates neurotransmission, g.i. motility, hemostasis, and cardiovascular integrity " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ
MP:0005323	dystonia	"impairment of muscle tone resulting in prolonged muscle contraction and involuntary movements such as repetitive movements, or twisting or writhing of the limbs" [J:84533]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0005404	abnormal axon morphology	"anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm7(CAG-mCherry,-EGFP/tetX)Dym}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺,Tg(Fev-flpe)1Dym/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ
MP:0005405	axon degeneration	"retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pink1^tm1Aub/Pink1^tm1Aub,Tg(Prnp-SNCAA53T)AAub/Tg(Prnp-SNCAA53T)AAub Genetic Background: involves: 129S/SvEv * FVB/N
MP:0005537	abnormal cerebral aqueduct	"anomalous structure of the channel in the mesencephalon that connets the third and fourth ventricles" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, hdene:Howard Dene , Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
MP:0005643	decreased dopamine level	"less than the normal concentration of this catecholamine neurotransmitter, dervied from tyrosine and the precursor to norepinephrine and epinephrine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:88298]	Show Allelic Composition: Gadd45b^tm1Flv/Gadd45b^tm1Flv,Gadd45g^tm1Flv/Gadd45g^tm1Flv Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0006035	abnormal mitochondrial morphology	"anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0006097	abnormal cerebellar lobule formation	"anomaly in the formation of the lobes of the cerebellum" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1 Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm2(cre)Gld/En1⁺,Gli2^tm1Alj/Gli2^tm6Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj
MP:0006098	absent cerebellar lobules	"missing lobes of the cerebellum" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Egfr^tm1Mag/Egfr^tm1Mag Genetic Background: involves: 129S2/SvPas * CD-1
MP:0006104	abnormal tectum morphology	"any structural alterations or malfunction of the rostral part of the midbrain roof" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator, J:65762]	Show Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/En1⁺,En2^tm2Alj/En2^tm2Alj,Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
MP:0006105	reduced tectum size	"reduced size of the rostral part of the midbrain roof" [smb:Susan M Bello, Mouse Genome Informatics Curator, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65410]	Show Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0006106	absent tectum	"absence or loss of the rostral part of the midbrain roof" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0006279	abnormal limb development	"anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj,Rfng^tm1Tfv/Rfng^tm1Tfv Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0008146	asymmetric rib-sternum attachment	"loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0008260	abnormal autophagy	"abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0008277	abnormal sternum ossification	"anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Gld/En1⁺,En2^tm1Alj/En2^tm1Alj Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster
MP:0008572	abnormal Purkinje cell dendrite morphology	"any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss
MP:0008730	fused phalanges	"anomaly of the long bones of the digits resulting in some or all the bones being joined together" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0008770	decreased survivor rate	"a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj
MP:0008874	decreased sensitivity to xenobiotics	"increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0008911	induced hyperactivity	"increased physical activity following stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0008918	microgliosis	"a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her
MP:0008948	decreased neuron number	"fewer than normal numbers of the cells of the nervous system that receive, conduct, and transmit impulses" [MESH:A08.663]	Show Allelic Composition: Crp^tm1Hjf/Crp^tm1Hjf,Ldlr^tm1Her/Ldlr^tm1Her Genetic Background: B6.Cg-Crp^tm1Hjf Ldlr^tm1Her Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6N Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0009038	decreased inferior colliculus size	"decreased size of the paired inferior eminence of the mesencephalic tectum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^tm4(en)Alj/En1^tm4(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm3(En2)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0009039	absent inferior colliculus	"absence of the paired inferior eminence of the mesencephalic tectum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1⁺,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0009040	absent superior colliculus	"absence of the paired superior eminence of the mesencephalic tectum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0009041	absent colliculi	"absence of the inferior and superior colliculus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2(cre)Wrst/En1^tm8.1Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129/Sv * Black Swiss * C57BL/6 * SJL * Swiss Webster Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster
MP:0009048	enlarged tectum	"increased size of the rostral part of the midbrain roof" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/?,Gli3^tm1Alj/Gli3^tm1Alj,Smo^tm2Amc/Smo^tm2Amc Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
MP:0009267	abnormal cerebellum fissure morphology	"any structural anomaly of the deep furrows which divide the lobules of the cerebellum, including the postcentral, primary and secondary furrows" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: En1^tm8.1Alj/En1⁺,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0009538	abnormal synapse morphology	"any strucutral anomaly of the membrane junction site of a nerve cell to a target cell, such as another nerve cell, an effector cell, or a sensory receptor cell; transmission of nerve impulses may be mediated by chemical or by electrical means" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MESH:A08.850]	Show Allelic Composition: Foxa2^tm1Jrt/Foxa2^tm1Khk,Tg(Nes-cre)1Wme/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
MP:0009546	absent gastric milk in neonates	"failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0009718	absent Purkinje cell layer	"there is no evidence of the cell layer that lies just underneath the molecular layer of the cerebellar cortex, normally containing the neuronal cell bodies of the Purkinje cells arranged side by side in a single layer, and candelabrum interneurons vertically oriented between the Purkinje cells" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Lhx1^tm1Tmj/Lhx1^tm2.1Bhr,Lhx5^tm1Lmgd/Lhx5^tm1Lmgd Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
MP:0009719	reduced cerebellar foliation	"the cerebellar lobules are reduced in size or number" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0009746	enhanced behavioral response to xenobiotic	"increased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or reduced dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0009754	enhanced behavioral response to cocaine	"increased sensitivity to cocaine resulting in a behavioral response, such as induced hyperactivity or stereotypic behavior, or decreased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0009779	enhanced behavioral response to anesthetic	"increase or exceleration in the behavioral changes that follow exposure to a given amount of an anesthetizing agent" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Drd2^tm3.1Ebo/Drd2^tm3.1Ebo,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6
MP:0009937	abnormal neuron differentiation	"abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gata2^tm1Msal/Gata2^tm1Msal Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0009957	abnormal cerebellum vermis lobule morphology	"any structural anomaly of the region of a cerebellar lobule that resides in the central section of the cerebellum between the two hemispheres; in humans, vermis lobule regions may be nearly continuous with the cerebellar hemisphere lobules dorsally but are separated by deeper longitudinal fissues in the ventral regions; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17506688]	Show Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm6Alj/En2⁺,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0009963	abnormal cerebellum hemisphere lobule morphology	"any structural anomaly of the region of a cerebellar lobule that resides in either of the lateral sections of the cerebellum outside the vermis; in mammals, the vermis portion of the cerebellum has a foliation pattern along the AP axis that is distinct from the lateral cerebellar hemispheres; distinct species specific differences in hemisphere lobulation occurs among mammals, with greatest complexity in primates" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:17506688, PMID:19693030]	Show Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm7.1Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster
MP:0009968	abnormal cerebellar granule cell proliferation	"any anomaly in the ability of a cerebellar granule cell population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster
MP:0010047	axonal spheroids	"focal 10-50 micron diameter swellings of axons, which are sometimes, but not always, terminal endbulbs, and are filled with disorganized neurofilaments, tubules, organelles or multi-lamellar inclusions" [PMID:15644421]	Show Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: En1^tm1Gld/En1⁺,En2^tm1Alj/En2^tm1Alj Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster
MP:0010149	abnormal synaptic dopamine release	"aberrant secretion across synapses of the catecholamine neurotransmitter and neurohormone, derived from tyrosine and the precursor to norepinephrine and epinephrine; functions as a neurotransmitter in the brain and as a hormone to inhibit the release of prolactin from the anterior lobe of the pituitary" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0011085	complete postnatal lethality	"premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Mfn2^tm1Dcc/Mfn2^tm3Dcc Genetic Background: involves: 129 * 129S4/SvJaeSor * Black Swiss Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.1Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Dnm1l^tm1.1Hise/Dnm1l^tm1.2Hise,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: B6.129-En1^tm1Alj Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: En1^tm1Alj/En1^tm1Alj Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J) Allelic Composition: En1^{tm1(Wnt1)Wrst}/En1^{tm1(Wnt1)Wrst} Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^{tm1.1(Wnt1)Wrst}/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: En1^{tm1(PDGFB)Nist}/En1^{tm1(PDGFB)Nist} Genetic Background: involves: 129/Sv * C57BL/6
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: En1^tm2Alj/En1^tm2Alj,En2^tm2Alj/En2⁺ Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj,En2^tm2Alj/En2^tm2Alj Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld,En2^tm1Alj/En2^tm1Alj Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld,En2^tm1Alj/En2⁺ Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^tm1Alj/En1^tm8.1Alj,En2^tm1Alj/En2^tm6Alj,Gt(ROSA)26Sor^{tm1(cre/ERT2)Alj}/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac
MP:0011090	partial perinatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Foxa2^tm1Jrt/Foxa2^tm1Khk,Tg(Nes-cre)1Wme/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA Allelic Composition: En1^tm1Alj/En1^tm1Alj,Wnt7a^tm1Amc/Wnt7a^tm1Amc,Tg(Wnt1-En1)1Amc/0 Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J)
MP:0011448	decreased dopaminergic neuron number	"fewer than normal numbers of the neurons that utilize dopamine as a neurotransmitter" [MGI:smb]	Show Allelic Composition: En1^tm1Gld/En1^tm1Gld,En2^tm1Alj/En2^tm1Alj Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld,En2^tm1Alj/En2⁺ Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.1Jyhl/Fgf8^tm1.3Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^{tm7(cre/ESR1)Alj}/0,Fgf8^tm1.3Mrt/Fgf8^tm1.4Mrt Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac Allelic Composition: En1^tm2Alj/En1⁺,Tg(Th-EGFP)6-7Okn/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J * OF1
MP:0011450	ectopic dopaminergic neuron	"abnormal location of one or more of the neurons that utilize dopamine as a neurotransmitter" [MGI:smb]	Show Allelic Composition: Cnga2^tm1Reed/Y Genetic Background: involves: 129/Sv * BALB/cJ
MP:0011940	decreased food intake	"reduction in the total number of calories/food amount taken in over time when compared to the normal state" [MGI:csmith]	Show Allelic Composition: En1^tm1Gld/En1⁺,En2^tm1Alj/En2^tm1Alj Genetic Background: involves: 129S/SvEv * 129S2/SvPas * C57BL/6 * Swiss Webster
MP:0012087	absent midbrain	"absence of the brain region derived from the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions in the adult, including eye movement and coordination of auditory and visual reflexes" [MGI:anna]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0012089	decreased midbrain size	"size reduction or truncation of the brain region derived from the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions in the adult, including eye movement and coordination of auditory and visual reflexes" [MGI:anna, MGI:csmith]	Show Allelic Composition: En1^tm5(en)Alj/En1^tm5(en)Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/En1⁺,En2^tm2Alj/En2^tm2Alj,Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: En1^tm1Gld/En1^tm1Gld Genetic Background: involves: 129S/SvEv * C57BL/6 Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
MP:0012132	abnormal midbrain-hindbrain boundary morphology	"any structural anomaly of the midbrain-hindbrain domain of the embryonic brain that is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; normally, an organizing center located at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [MGI:anna]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0012133	absent midbrain-hindbrain boundary	"absence of the midbrain-hindbrain domain of the embryonic brain that is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages; normally, an organizing center located at the boundary patterns the midbrain and hindbrain primordia of the neural plate" [MGI:anna]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0012267	abnormal red nucleus morphology	"any anomaly of the pale pink structure located in the tegmentum of the midbrain next to the substantia nigra and involved in motor coordination" [MGI:anna]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm1Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Tor1a^tm2Wtd/Tor1a^tm3.1Wtd Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6J * SJL
MP:0012703	decreased embryonic neuroepithelium thickness	"reduced width of the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [MGI:anna]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0012706	decreased embryonic neuroepithelial cell proliferation	"decrease in the expansion rate of the cells of the embryonic neuroepithelium by cell division" [CL:0000710, MGI:anna]	Show Allelic Composition: En1^tm2(cre)Wrst/En1⁺,Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
MP:0012785	decreased rhombomere 1 size	"reduced size of the first transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order with the first rhombomere arising next to the midbrain-hindbrain boundary, or isthmus" [MGI:anna]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss Allelic Composition: En1^tm2Alj/En1^tm2Alj Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster Allelic Composition: En1^{tm7(cre/ESR1)Alj}/En1⁺,En2^tm2Alj/En2^tm2Alj,Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129S6/SvEvTac * 129X1/SvJ * Swiss Webster Allelic Composition: Wnt1^tm1.1Mze/Wnt1^tm1.1Mze,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6N
MP:0012787	absent rhombomere 1	"absence of the first transiently divided segment of the developing rhombencephalon; rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates; rhombomeres are numbered in caudal to rostral order with the first rhombomere arising next to the midbrain-hindbrain boundary, or isthmus" [MGI:anna]	Show Allelic Composition: Foxc1^tm1Blh/Foxc1^tm1Blh,Foxc2^tm1Blh/Foxc2^tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
MP:0013219	abnormal substantia nigra pars compacta morphology	"any structural anomaly of the posterior (dorsal) part of grey matter of the substantia nigra which contains large, polygonal, and densely packed dopamine-producing cells; pars compacta neurons are pigmented in many species" [MGI:anna]	Show Allelic Composition: Atg7^tm1Tchi/Atg7^tm1Tchi,En1^tm2(cre)Wrst/En1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrlj

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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