ENSMUSG00000060924


Mus musculus

Features
Gene ID: ENSMUSG00000060924
  
Biological name :Csmd1
  
Synonyms : Csmd1 / CUB and sushi domain-containing protein 1 / Q923L3
  
Possible biological names infered from orthology : CUB and Sushi multiple domains 1
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: A1.3
Gene start: 15892537
Gene end: 17535586
  
Corresponding Affymetrix probe sets: 10577240 (MoGene1.0st)   1421449_at (Mouse Genome 430 2.0 Array)   1445531_at (Mouse Genome 430 2.0 Array)   1446273_at (Mouse Genome 430 2.0 Array)   1446468_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080751
NCBI entrez gene - 94109     See in Manteia.
MGI - MGI:2137383
RefSeq - XM_006508931
RefSeq - NM_053171
RefSeq - XM_006508930
RefSeq Peptide - NP_444401
swissprot - Q923L3
Ensembl - ENSMUSG00000060924
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CSMD1ENSGALG00000035230Gallus gallus
 CSMD1ENSG00000183117Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Csmd2 / CUB and Sushi multiple domains 2 / Q7Z408*ENSMUSG0000002880465
Csmd3 / Q80T79 / CUB and sushi domain-containing protein 3 / Q7Z407* / CUB and Sushi multiple domains 3*ENSMUSG0000002231163
Svep1 / A2AVA0 / Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 / Q4LDE5* / sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1*ENSMUSG0000002836922
Cr2 / complement C3d receptor 2 / P20023*ENSMUSG000000266167
Sez6 / Q7TSK2 / Seizure protein 6 / Q53EL9* / seizure related 6 homolog*ENSMUSG000000006326
Sez6l / Q6P1D5 / seizure related 6 homolog like / Q9BYH1*ENSMUSG000000581536
Q4V9Z5 / Sez6l2 / Seizure 6-like protein 2 / Q6UXD5* / seizure related 6 homolog like 2*ENSMUSG000000306835
Cr1l / Q64735 / Mus musculus complement component (3b/4b) receptor 1-like (Cr1l), transcript variant 2, mRNA. / Q2VPA4* / complement C3b/C4b receptor 1 like*ENSMUSG000000164813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR000859  CUB domain
 IPR035914  Spermadhesin, CUB domain superfamily
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001964 startle response IMP
 biological_processGO:0042593 glucose homeostasis IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002572 abnormal emotion/affect behavior "altered response in tests for emotional related behaviors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002573 behavioral despair "depression assayed by reduced escape attempts and/or immobility when placed in a stressful situation such as a forced swim test or a suspension test; or failure to seek pleasurable stimuli" [J:80395]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0002797 thigmotaxis "preference of a mouse for the side walls of a cage or box; usually an indicator of increased anxiety response" [J:56814]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003491 abnormal voluntary movement "anomalies in coordinated movements executed with a purpose and can be improved by learning and/or experience" [Nmice:Neuromice Consortium Submission]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Grin1tm1Jjwd/Grin1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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