ENSDARG00000015076


Danio rerio
connexinjunctiongja8bgapmembraneproteincellplasmaintegralcomponentalpha-cxn-terminalconservedsitecysteine-richdomainc-terminalcommunicationtransmembranetransportcomplexhemi-channelactivity

Features
Gene ID: ENSDARG00000015076
  
Biological name :gja8b
  
Synonyms : gap junction protein alpha 8 paralog b / gja8b
  
Possible biological names infered from orthology : gap junction protein alpha 8 / GJA8 / P28236 / P48165
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 47446032
Gene end: 47448850
  
Corresponding Affymetrix probe sets: Dr.10459.1.S1_at (Zebrafish Array)   NM_131809_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026053
Ensembl peptide - ENSDARP00000106191
NCBI entrez gene - 114403     See in Manteia.
RefSeq - NM_131809
RefSeq Peptide - NP_571884
swissprot - Q503J6
ZFIN ID - ZDB-GENE-010607-3
Ensembl - ENSDARG00000015076
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GJA8ENSGALG00000015488Gallus gallus
 GJA8ENSG00000121634Homo sapiens
 Gja8ENSMUSG00000049908Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gja8a / gap junction protein alpha 8 paralog a / GJA8* / P28236* / P48165* / gap junction protein alpha 8*ENSDARG0000006945173
gja3 / gap junction protein, alpha 3 / Q64448* / Q9Y6H8*ENSDARG0000002188948
cx39.9 / connexin 39.9ENSDARG0000000408242
gja5a / gap junction protein, alpha 5a / GJA5* / P36382* / Q01231* / gap junction protein alpha 5*ENSDARG0000004006540
cx43 / O57474 / connexin 43ENSDARG0000004179939
gja5b / gap junction protein, alpha 5b / GJA5* / P36382* / Q01231* / gap junction protein alpha 5*ENSDARG0000006945039
cx52.9 / connexin 52.9 / GJA9* / P57773* / gap junction protein alpha 9*ENSDARG0000008645337
cx52.6 / connexin 52.6 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000003493036
cx52.7 / connexin 52.7 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000005779236
cx40.8 / connexin 40.8 / GJA1* / P23242* / P17302* / gap junction protein alpha 1*ENSDARG0000007119236
cx32.3 / connexin 32.3ENSDARG0000004178735
cx34.5 / connexin 34.5ENSDARG0000006941135
cx28.9 / connexin 28.9ENSDARG0000004179733
cx39.4 / connexin 39.4 / GJA4* / P35212* / P28235* / gap junction protein alpha 4*ENSDARG0000007035732
cx32.2 / Q7T047 / connexin 32.2ENSDARG0000007678931
cx43.4 / connexin 43.4ENSDARG0000000709930
gjd2b / gap junction protein delta 2b / GJD2* / O54851* / Q9UKL4* / gap junction protein delta 2*ENSDARG0000007078130
cx44.2 / connexin 44.2 / si:dkey-91f15.8ENSDARG0000003420729
cx28.1 / connexin 28.1ENSDARG0000004179229
cx47.1 / connexin 47.1 / GJC2* / Q8BQU6* / Q5T442* / gap junction protein gamma 2*ENSDARG0000007389628


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002266  Gap junction alpha-8 protein (Cx50)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain
 IPR034634  Connexin, C-terminal


Gene Ontology (GO)
cell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationestablishment of localizationcell communicationcell communicationestablishment of localizationestablishment of localization
transmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activitytransmembrane transporter activity
cellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellmembranecell junctionprotein-containing complexcellcellmembranemembranecell junctioncell junctionprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IC
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0055077 gap junction hemi-channel activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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