ENSDARG00000069450


Danio rerio

Features
Gene ID: ENSDARG00000069450
  
Biological name :gja5b
  
Synonyms : gap junction protein, alpha 5b / gja5b
  
Possible biological names infered from orthology : gap junction protein alpha 5 / GJA5 / P36382 / Q01231
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 47414734
Gene end: 47431453
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091879
NCBI entrez gene - 570445     See in Manteia.
RefSeq - NM_001034988
RefSeq Peptide - NP_001030160
swissprot - B3DID2
ZFIN ID - ZDB-GENE-050616-11
Ensembl - ENSDARG00000069450
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000042735Gallus gallus
 GJA5ENSGALG00000039452Gallus gallus
 GJA5ENSG00000265107Homo sapiens
 Gja5ENSMUSG00000057123Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gja5a / gap junction protein, alpha 5a / GJA5* / P36382* / Q01231* / gap junction protein alpha 5*ENSDARG0000004006564
gja3 / gap junction protein, alpha 3 / Q64448* / Q9Y6H8*ENSDARG0000002188945
cx39.9 / connexin 39.9ENSDARG0000000408241
gja8b / gap junction protein alpha 8 paralog b / GJA8* / P28236* / P48165* / gap junction protein alpha 8*ENSDARG0000001507641
cx43 / O57474 / connexin 43ENSDARG0000004179939
gja8a / gap junction protein alpha 8 paralog a / GJA8* / P28236* / P48165* / gap junction protein alpha 8*ENSDARG0000006945139
cx52.6 / connexin 52.6 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000003493036
cx52.7 / connexin 52.7 / GJA10* / Q9WUS4* / Q969M2* / gap junction protein alpha 10*ENSDARG0000005779236
cx52.9 / connexin 52.9 / GJA9* / P57773* / gap junction protein alpha 9*ENSDARG0000008645336
cx34.5 / connexin 34.5ENSDARG0000006941135
cx40.8 / connexin 40.8 / GJA1* / P23242* / P17302* / gap junction protein alpha 1*ENSDARG0000007119235
cx32.3 / connexin 32.3ENSDARG0000004178733
cx28.9 / connexin 28.9ENSDARG0000004179732
cx39.4 / connexin 39.4 / GJA4* / P35212* / P28235* / gap junction protein alpha 4*ENSDARG0000007035732
cx47.1 / connexin 47.1 / GJC2* / Q8BQU6* / Q5T442* / gap junction protein gamma 2*ENSDARG0000007389629
cx32.2 / Q7T047 / connexin 32.2ENSDARG0000007678929
cx43.4 / connexin 43.4ENSDARG0000000709928
cx44.2 / connexin 44.2 / si:dkey-91f15.8ENSDARG0000003420728
cx28.1 / connexin 28.1ENSDARG0000004179228
cx36.7 / connexin 36.7ENSDARG0000001792726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000500  Connexin
 IPR002264  Gap junction alpha-5 protein (Cx40)
 IPR013092  Connexin, N-terminal
 IPR017990  Connexin, conserved site
 IPR019570  Gap junction protein, cysteine-rich domain
 IPR031862  Gap junction alpha-5 protein (Cx40), C-terminal
 IPR034634  Connexin, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097324 melanocyte migration IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0005922 connexin complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0055077 gap junction hemi-channel activity IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain acetylcholinesterase activity increased process quality , abnormal
Show

 ZFA:0000368 integument integument pigmentation disrupted , abnormal
Show

 ZFA:0001058 caudal fin caudal fin melanophore stripe spotted , abnormal
caudal fin melanophore stripe absent , abnormal
caudal fin melanocyte decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism spotted , abnormal
whole organism has fewer parts of type melanocyte , abnormal
whole organism dappled , abnormal
Show

 ZFA:0001162 anal fin anal fin has fewer parts of type melanocyte , abnormal
anal fin has fewer parts of type xanthophore , abnormal
anal fin spotted , abnormal
anal fin melanophore stripe patchy , abnormal
anal fin melanophore stripe undulate , abnormal
anal fin melanophore stripe spotted , abnormal
anal fin melanophore stripe absent , abnormal
anal fin melanocyte decreased amount , abnormal
Show

 ZFA:0001463 melanophore stripe melanophore stripe spatial pattern , abnormal
melanophore stripe spotted , abnormal
melanophore stripe absent , abnormal
melanophore stripe broken , abnormal
melanophore stripe irregular spatial pattern , abnormal
melanophore stripe patchy , abnormal
melanophore stripe increased width , abnormal
melanophore stripe undulate , abnormal
melanophore stripe disheveled , abnormal
melanophore stripe decreased width , abnormal
melanophore stripe morphology , abnormal
Show

 ZFA:0009090 pigment cell pigment cell spatial pattern , abnormal
pigment cell quality , abnormal
pigment cell irregular spatial pattern , abnormal
Show

 ZFA:0009091 melanocyte melanocyte disorganized , abnormal
melanocyte dispersed , abnormal
melanocyte distributed , abnormal
Show

 ZFA:0009198 xanthophore xanthophore absent , abnormal
Show

 ZFA:0009199 iridophore iridophore pigmentation process quality , abnormal
iridophore absent , abnormal
iridophore dispersed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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