ENSDARG00000024785


Danio rerio

Features
Gene ID: ENSDARG00000024785
  
Biological name :ctnna2
  
Synonyms : B7ZC77 / catenin (cadherin-associated protein), alpha 2 / ctnna2
  
Possible biological names infered from orthology : catenin alpha 2 / Mus musculus catenin (cadherin associated protein), alpha 2 (Ctnna2), transcript variant 4, mRNA. / P26232 / Q61301
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 42224769
Gene end: 43039672
  
Corresponding Affymetrix probe sets: Dr.18619.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118591
Ensembl peptide - ENSDARP00000156262
Ensembl peptide - ENSDARP00000143454
Ensembl peptide - ENSDARP00000129168
Ensembl peptide - ENSDARP00000123176
Ensembl peptide - ENSDARP00000092080
Ensembl peptide - ENSDARP00000098352
NCBI entrez gene - 567500     See in Manteia.
swissprot - B8JKG9
swissprot - B8A6A9
swissprot - B7ZC77
swissprot - A0A286Y8G3
swissprot - F1Q548
swissprot - X1WG13
ZFIN ID - ZDB-GENE-060815-3
Ensembl - ENSDARG00000024785
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015966Gallus gallus
 CTNNA2ENSGALG00000027853Gallus gallus
 CTNNA2ENSG00000066032Homo sapiens
 Ctnna2ENSMUSG00000063063Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ctnna1 / catenin (cadherin-associated protein), alpha 1 / P26231* / P35221* / catenin alpha 1*ENSDARG0000010244183
ctnnal1 / catenin (cadherin-associated protein), alpha-like 1 / O88327* / Q9UBT7* / Alpha-catulin * / catenin alpha like 1*ENSDARG0000001816223
vcla / vinculin a / VCL* / Q64727* / P18206* / vinculin*ENSDARG0000004496823
vcla / vinculin a / VCL* / P18206* / vinculin*ENSDARG0000009869520


Protein motifs (from Interpro)
Interpro ID Name
 IPR000633  Vinculin, conserved site
 IPR001033  Alpha-catenin
 IPR006077  Vinculin/alpha-catenin
 IPR030046  Alpha N-catenin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007409 axonogenesis ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048813 dendrite morphogenesis ISS
 biological_processGO:0048854 brain morphogenesis IEA
 biological_processGO:0051823 regulation of synapse structural plasticity ISS
 biological_processGO:0098609 cell-cell adhesion ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005912 adherens junction ISS
 cellular_componentGO:0005913 cell-cell adherens junction IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042021 O42376 / mapk12a / mitogen-activated protein kinase 12a / O08911* / MAPK12* / P53778* / mitogen-activated protein kinase 12*  / complex
 ENSDARG00000014571 ctnnb1 / catenin (cadherin-associated protein), beta 1 / P35222* / catenin beta 1*  / complex
 ENSDARG00000045836 mapk11 / mitogen-activated protein kinase 11 / Q15759* / Q9WUI1*  / complex
 ENSDARG00000006409 mapk12b / mitogen-activated protein kinase 12b / P53778* / MAPK12* / O08911* / mitogen-activated protein kinase 12*  / complex
 ENSDARG00000028721 mapk14b / mitogen-activated protein kinase 14b / Q16539* / MAPK14* / P47811* / mitogen-activated protein kinase 14*  / complex
 ENSDARG00000000857 Q9DGE2 / mapk14a / mitogen-activated protein kinase 14a / P47811* / Q16539* / MAPK14* / mitogen-activated protein kinase 14*  / complex
 ENSDARG00000013397 bnip2 / BCL2 interacting protein 2 / O54940* / Q12982* / BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 *  / complex
 ENSDARG00000068191 cdh15 / cadherin 15, type 1, M-cadherin (myotubule) / P33146* / P55291* / cadherin 15*  / complex
 ENSDARG00000061328 cdon / cell adhesion associated, oncogene regulated / Q32MD9* / Q4KMG0* / Cell adhesion molecule-related/down-regulated by oncos *  / complex / reaction
 ENSDARG00000024785 B7ZC77 / ctnna2 / catenin (cadherin-associated protein), alpha 2 / Q61301* / P26232* / catenin alpha 2* / Mus musculus catenin (cadherin associated protein), alpha 2 (Ctnna2), transcript va...  / complex
 ENSDARG00000044573 cdc42 / cell division cycle 42 / P60766* / P60953* / Cell division control *  / complex
 ENSDARG00000102441 ctnna1 / catenin (cadherin-associated protein), alpha 1 / P26231* / P35221* / catenin alpha 1*  / complex
 ENSDARG00000035187 abl1 / c-abl oncogene 1, non-receptor tyrosine kinase / P00519* / P00520* / ABL proto-oncogene 1, non-receptor tyrosine kinase*  / complex






 

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