ENSDARG00000039563


Danio rerio

Features
Gene ID: ENSDARG00000039563
  
Biological name :loxl3b
  
Synonyms : B8A4W9 / loxl3b / lysyl oxidase-like 3b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 15234521
Gene end: 15404571
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000103878
Ensembl peptide - ENSDARP00000105131
Ensembl peptide - ENSDARP00000109545
NCBI entrez gene - 336266     See in Manteia.
swissprot - B8A4W9
ZFIN ID - ZDB-GENE-030131-8210
Ensembl - ENSDARG00000039563
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
F1RD85 / loxl3a / lysyl oxidase-like 3aENSDARG0000007630669
F1QQC3 / loxl2a / lysyl oxidase-like 2a / LOXL2* / Q9Y4K0* / lysyl oxidase like 2*ENSDARG0000004401053
loxl2b / A1L1V4 / lysyl oxidase-like 2b / LOXL2* / Q9Y4K0* / P58022* / lysyl oxidase like 2* / Lysyl oxidase homolog 2 *ENSDARG0000004407453
loxl4 / lysyl oxidase-like 4ENSDARG0000002508948
si:cabz01100188.1ENSDARG0000010544225
loxl1 / lysyl oxidase-like 1 / Q08397*ENSDARG0000005445119
loxa / lysyl oxidase aENSDARG0000000325917
loxl5b / lysyl oxidase-like 5bENSDARG0000007690417
loxl5a / lysyl oxidase-like 5aENSDARG0000007168016
si:dkey-242e21.3 / CD6* / P30203* / Q61003* / CD6 molecule* / T-cell differentiation antigen CD6 *ENSDARG0000007572311
si:dkey-21h14.3ENSDARG0000009604711
scara5 / Q5RFW0 / scavenger receptor class A, member 5 (putative) / Q8K299* / Q6ZMJ2* / scavenger receptor class A member 5*ENSDARG000000104259
si:ch211-150o23.3ENSDARG000000785029
marco / macrophage receptor with collagenous structure / Q9UEW3*ENSDARG000000592948
CT583642.2ENSDARG000001113156


Protein motifs (from Interpro)
Interpro ID Name
 IPR001190  SRCR domain
 IPR001695  Lysyl oxidase
 IPR013783  Immunoglobulin-like fold
 IPR017448  SRCR-like domain
 IPR019828  Lysyl oxidase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0006954 inflammatory response ISS
 biological_processGO:0018057 peptidyl-lysine oxidation ISS
 biological_processGO:0021510 spinal cord development ISS
 biological_processGO:0030324 lung development ISS
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060021 roof of mouth development ISS
 biological_processGO:0061053 somite development ISS
 biological_processGO:1905590 fibronectin fibril organization ISS
 biological_processGO:2000329 negative regulation of T-helper 17 cell lineage commitment ISS
 biological_processGO:2001046 positive regulation of integrin-mediated signaling pathway ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0001968 fibronectin binding ISS
 molecular_functionGO:0004720 protein-lysine 6-oxidase activity ISS
 molecular_functionGO:0005044 scavenger receptor activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord kinked , abnormal
Show

 ZFA:0001205 Meckel s cartilage Meckels cartilage malformed , abnormal
Show

 ZFA:0001321 neurocranial trabecula neurocranial trabecula decreased size , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage malformed , abnormal
pharyngeal arch cartilage immature , abnormal
Show

 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage absent , abnormal
ceratobranchial cartilage malformed , abnormal
ceratobranchial cartilage supramolecular fiber increased amount , abnormal
ceratobranchial cartilage supramolecular fiber increased thickness , abnormal
ceratobranchial cartilage chondrocyte decreased size , abnormal
ceratobranchial cartilage chondrocyte immature , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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