ENSGALG00000017186


Gallus gallus

Features
Gene ID: ENSGALG00000017186
  
Biological name :BIRC2
  
Synonyms : BIRC2
  
Possible biological names infered from orthology : baculoviral IAP repeat containing 2 / baculoviral IAP repeat containing 3 / Baculoviral IAP repeat-containing protein 2 / BIRC3 / Q13489 / Q13490 / Q62210
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 182634266
Gene end: 182644438
  
Corresponding Affymetrix probe sets: Gga.4384.1.S1_at (Chicken Array)   Gga.4384.1.S2_at (Chicken Array)   Gga.4384.1.S2_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000035646
Ensembl peptide - ENSGALP00000058777
NCBI entrez gene - 374012     See in Manteia.
RefSeq - NM_001007822
RefSeq Peptide - NP_001007823
swissprot - A0A1L1RJ49
swissprot - A0A140T8H6
Ensembl - ENSGALG00000017186
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 birc2ENSDARG00000044619Danio rerio
 BIRC2ENSG00000110330Homo sapiens
 BIRC3ENSG00000023445Homo sapiens
 Birc2ENSMUSG00000057367Mus musculus
 Birc3ENSMUSG00000032000Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
XIAP / BIRC8* / P98170* / Q60989* / Q96P09* / X-linked inhibitor of apoptosis* / baculoviral IAP repeat containing 8*ENSGALG0000000849132
BIRC7 / baculoviral IAP repeat containing 7 / A2AWP0* / Q96CA5* / Baculoviral IAP repeat-containing protein 7 Baculoviral IAP repeat-containing protein 7 30 kDa subunit*ENSGALG0000000576226


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR001370  BIR repeat
 IPR001841  Zinc finger, RING-type
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042981 regulation of apoptotic process IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
TNFR2 non-canonical NF-kB pathway
Regulation of necroptotic cell death
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
Ub-specific processing proteases
IKK complex recruitment mediated by RIP1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006415 CD40LG / Q9I8D8 / CD40 ligand CD40 ligand, membrane form CD40 ligand, soluble form / P27548* / P29965* / CD40 ligand*  / complex / reaction
 ENSGALG00000011389 TRAF3 / TNF receptor associated factor 3 / Q13114* / Q60803*  / complex / reaction
 ENSGALG00000021213 UBE2D1 / ubiquitin conjugating enzyme E2 D1 / P51668* / P61080*  / complex
 ENSGALG00000006824 USP19 / ubiquitin specific peptidase 19 / O94966* / Q3UJD6*  / complex / reaction
 ENSGALG00000016852 TNFSF13B / Q9WU72* / Q9Y275* / TNF superfamily member 13b* / tumor necrosis factor (ligand) superfamily, member 13b*  / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000007015 CD40 / tumor necrosis factor receptor superfamily member 5 precursor / P25942* / P27512* / CD40 molecule* / Tumor necrosis factor receptor superfamily member 5 *  / complex / reaction
 ENSGALG00000038128 UBE2D2 / ubiquitin conjugating enzyme E2 D2 / P62838* / P62837* / Ube2d2a* / ubiquitin-conjugating enzyme E2D 2A*  / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000010638 CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*  / reaction
 ENSGALG00000012827 RIPK1 / receptor interacting serine/threonine kinase 1 / Q13546* / Q60855* / Receptor-interacting serine/threonine-protein kinase 1 *  / complex / reaction






 

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