ENSDARG00000002002


Danio rerio

Features
Gene ID: ENSDARG00000002002
  
Biological name :lmcd1
  
Synonyms : LIM and cysteine-rich domains 1 / lmcd1
  
Possible biological names infered from orthology : Q8VEE1 / Q9NZU5
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 39096911
Gene end: 39108026
  
Corresponding Affymetrix probe sets: Dr.17244.1.S1_at (Zebrafish Array)   NM_201070_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000128272
Ensembl peptide - ENSDARP00000127675
NCBI entrez gene - 394045     See in Manteia.
RefSeq - NM_201070
RefSeq Peptide - NP_957364
swissprot - E7FCK0
swissprot - X1WBT3
ZFIN ID - ZDB-GENE-040426-1067
Ensembl - ENSDARG00000002002
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LMCD1ENSGALG00000008349Gallus gallus
 LMCD1ENSG00000071282Homo sapiens
 Lmcd1ENSMUSG00000057604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tes / testis derived transcript (3 LIM domains) / Gm4985* / Q9UGI8* / Gm4907* / testin LIM domain protein* / testis derived transcript*ENSDARG0000005185744
prickle3 / prickle homolog 3 / O43900* / Q80VL3* / prickle planar cell polarity protein 3*ENSDARG0000007399633
prickle1a / prickle homolog 1a / Q96MT3* / Q3U5C7* / PRICKLE1* / Prickle-like protein 1 * / prickle planar cell polarity protein 1*ENSDARG0000004064928
prickle2b / prickle homolog 2b / Q7Z3G6* / Q80Y24* / PRICKLE2* / prickle planar cell polarity protein 2*ENSDARG0000003759327
prickle1b / prickle homolog 1b / Q96MT3* / Q3U5C7* / PRICKLE1* / Prickle-like protein 1 * / prickle planar cell polarity protein 1*ENSDARG0000004569426
prickle2a / prickle homolog 2a / Q7Z3G6* / PRICKLE2* / prickle planar cell polarity protein 2*ENSDARG0000002098226


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR010442  PET domain
 IPR033724  PET testin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003714 transcription corepressor activity IBA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Surfactant metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005064 atrioventricular valve atrioventricular valve closure , abnormal
atrioventricular valve structure , abnormal
atrioventricular valve functionality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000103589 gata6 / GATA binding protein 6 / Q61169* / Q92908* / Transcription factor GATA-6 *  / reaction / complex






 

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