ENSDARG00000002945


Danio rerio

Features
Gene ID: ENSDARG00000002945
  
Biological name :bgnb
  
Synonyms : bgnb / biglycan b
  
Possible biological names infered from orthology : BGN / biglycan / P21810 / P28653
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 20014030
Gene end: 20051369
  
Corresponding Affymetrix probe sets: Dr.16232.1.A1_at (Zebrafish Array)   NM_001001825_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000049835
NCBI entrez gene - 792197     See in Manteia.
RefSeq - NM_001001825
RefSeq Peptide - NP_001001825
swissprot - B7ZDB5
ZFIN ID - ZDB-GENE-040426-21
Ensembl - ENSDARG00000002945
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BGNENSG00000182492Homo sapiens
 BgnENSMUSG00000031375Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bgna / biglycan a / BGN* / P21810* / P28653* / biglycan*ENSDARG0000001788466
dcn / decorin / P07585* / P28654*ENSDARG0000001206651
aspn / asporin (LRR class 1) / Q99MQ4* / Q9BXN1* / asporin*ENSDARG0000000219248
zgc:113307ENSDARG0000004489428
prelp / proline/arginine-rich end leucine-rich repeat protein / Q9JK53* / P51888* / proline arginine-rich end leucine-rich repeat* / proline and arginine rich end leucine rich repeat protein*ENSDARG0000007059727
lum / lumican / P51884* / P51885*ENSDARG0000004558027
ecm2 / extracellular matrix protein 2, female organ and adipocyte specific / O94769* / Q5FW85* / extracellular matrix protein 2*ENSDARG0000007154927
fmoda / fibromodulin a / FMOD* / P50608* / Q06828* / fibromodulin*ENSDARG0000004489527
fmodb / fibromodulin b / FMOD* / P50608* / Q06828* / fibromodulin*ENSDARG0000001029426
si:dkey-6n6.1ENSDARG0000006248725
kera / Q5RI43 / keratocan / O35367* / O60938*ENSDARG0000005693824
omd / osteomodulin / O35103* / Q99983*ENSDARG0000009360023
si:dkey-32e6.6ENSDARG0000007085723
wu:fc23c09ENSDARG0000008800223
podn / podocan / Q7TQ62* / Q7Z5L7*ENSDARG0000001902521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR016352  Small leucine-rich proteoglycan, class I, decorin/asporin/byglycan
 IPR028547  Biglycan
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr