ENSDARG00000007891


Danio rerio

Features
Gene ID: ENSDARG00000007891
  
Biological name :meox1
  
Synonyms : F1Q4R9 / meox1 / mesenchyme homeobox 1
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 27462225
Gene end: 27469267
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000096438
NCBI entrez gene - 436723     See in Manteia.
swissprot - F1Q4R9
ZFIN ID - ZDB-GENE-040718-149
Ensembl - ENSDARG00000007891
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MEOX1ENSGALG00000001191Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
meox2b / mesenchyme homeobox 2b / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000006181843
meox2a / mesenchyme homeobox 2a / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000004091140
gbx2 / gastrulation brain homeobox 2 / P48031* / P52951* / Homeobox protein GBX-2 *ENSDARG0000000293321
gbx1 / gastrulation brain homeobox 1 / P82976* / Q14549* / Homeobox protein GBX-1 *ENSDARG0000007141819
mnx1 / motor neuron and pancreas homeobox 1 / P50219* / Q9QZW9*ENSDARG0000003598418
nkx1.2la / NK1 transcription factor related 2-like,a / Q9UD57* / NKX1-2* / P42580* / NK1 homeobox 2* / NK1 transcription factor-related protein 2 *ENSDARG0000000635017
nkx1.2lb / NK1 transcription factor related 2-like,b / Q15270* / NKX1-1* / NK1 homeobox 1* / NK1 transcription factor-related protein 1 *ENSDARG0000009942717
mnx2b / motor neuron and pancreas homeobox 2bENSDARG0000003035017
evx2 / even-skipped homeobox 2ENSDARG0000005925517
vox / ventral homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000009976116
mnx2a / motor neuron and pancreas homeobox 2aENSDARG0000004210616
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000010008715
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000009936515
pnx / F1R2J1 / posterior neuron-specific homeoboxENSDARG0000002589915
ved / ventrally expressed dharma/bozozok antagonistENSDARG0000010238914
vent / ventral expressed homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000010048314
eve1 / even-skipped-like1ENSDARG0000005601213


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0055001 muscle cell development IMP
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 biological_processGO:0061053 somite development ISS
 biological_processGO:0061056 sclerotome development ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding ISS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain quality , abnormal
hindbrain morphology , abnormal
hindbrain deformed , abnormal
Show

 ZFA:0000155 somite somite quality , abnormal
somite slow muscle cell disorganized , abnormal
somite slow muscle cell decreased amount , abnormal
somite fast muscle cell decreased amount , abnormal
Show

 ZFA:0000175 posterior lateral line nerve posterior lateral line nerve misrouted , abnormal
posterior lateral line nerve truncated , abnormal
Show

 ZFA:0000200 dorsal root ganglion dorsal root ganglion increased amount , abnormal
Show

 ZFA:0000207 fin musculature fin musculature muscle hypoplastic , abnormal
Show

 ZFA:0000473 trunk musculature trunk musculature muscle hypoplastic , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein increased diameter , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum hypoplastic , abnormal
Show

 ZFA:0001056 myotome myotome slow muscle cell decreased amount , abnormal
myotome fast muscle cell decreased amount , abnormal
Show

 ZFA:0001085 hypaxial myotome region hypaxial myotome region muscle malformed , abnormal
hypaxial myotome region muscle hypoplastic , abnormal
Show

 ZFA:0001089 myoseptum myoseptum quality , abnormal
myoseptum hypoplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism lacks all parts of type horizontal myoseptum , abnormal
Show

 ZFA:0001115 trunk trunk melanophore stripe branched , abnormal
trunk melanophore stripe curved , abnormal
trunk melanophore stripe malformed , abnormal
trunk melanocyte mislocalised , abnormal
trunk iridophore mislocalised , abnormal
Show

 ZFA:0001157 posterior lateral line primordium posterior lateral line primordium misrouted , abnormal
Show

 ZFA:0001651 sternohyoid sternohyoid hypoplastic , abnormal
Show

 ZFA:0005145 muscle muscle hypoplastic , abnormal
Show

 ZFA:0005223 lateral larval melanophore stripe lateral larval melanophore stripe absent , abnormal
Show

 ZFA:0009053 sensory neuron sensory neuron mislocalised , abnormal
Show

 ZFA:0009090 pigment cell pigment cell quality , abnormal
pigment cell irregular spatial pattern , abnormal
Show

 ZFA:0009091 melanocyte melanocyte irregular spatial pattern , abnormal
melanocyte mislocalised , abnormal
melanocyte decreased amount , abnormal
melanocyte position , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell mislocalised , abnormal
Show

 ZFA:0009198 xanthophore xanthophore decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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