ENSDARG00000030350


Danio rerio

Features
Gene ID: ENSDARG00000030350
  
Biological name :mnx2b
  
Synonyms : mnx2b / motor neuron and pancreas homeobox 2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 5449777
Gene end: 5455502
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000100110
Ensembl peptide - ENSDARP00000040367
NCBI entrez gene - 406206     See in Manteia.
RefSeq - NM_001009887
RefSeq - NM_001328358
RefSeq Peptide - NP_001009887
RefSeq Peptide - NP_001315287
swissprot - A2CEW5
swissprot - F1RCJ6
ZFIN ID - ZDB-GENE-040415-2
Ensembl - ENSDARG00000030350
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011349Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mnx2a / motor neuron and pancreas homeobox 2aENSDARG0000004210658
mnx1 / motor neuron and pancreas homeobox 1 / P50219* / Q9QZW9*ENSDARG0000003598443
gbx1 / gastrulation brain homeobox 1 / P82976* / Q14549* / Homeobox protein GBX-1 *ENSDARG0000007141820
gbx2 / gastrulation brain homeobox 2 / P48031* / P52951* / Homeobox protein GBX-2 *ENSDARG0000000293318
evx2 / even-skipped homeobox 2ENSDARG0000005925518
nkx1.2lb / NK1 transcription factor related 2-like,b / Q15270* / NKX1-1* / NK1 homeobox 1* / NK1 transcription factor-related protein 1 *ENSDARG0000009942718
vox / ventral homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000009976116
meox2a / mesenchyme homeobox 2a / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000004091115
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000010008715
nkx1.2la / NK1 transcription factor related 2-like,a / Q9UD57* / NKX1-2* / P42580* / NK1 homeobox 2* / NK1 transcription factor-related protein 2 *ENSDARG0000000635015
meox2b / mesenchyme homeobox 2b / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000006181814
ved / ventrally expressed dharma/bozozok antagonistENSDARG0000010238914
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000009936513
eve1 / even-skipped-like1ENSDARG0000005601213
meox1 / F1Q4R9 / mesenchyme homeobox 1ENSDARG0000000789113
pnx / F1R2J1 / posterior neuron-specific homeoboxENSDARG0000002589913
vent / ventral expressed homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000010048311


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021520 spinal cord motor neuron cell fate specification IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005179 MiP motor neuron MiP motor neuron lacks parts or has fewer parts of type MiP motor neuron axon, abnormal
MiP motor neuron axon mislocalised , abnormal
MiP motor neuron axon truncated , abnormal
MiP motor neuron axon physical object quality , abnormal
Show

 ZFA:0005754 primary islet primary islet elongated , abnormal
Show

 ZFA:0009243 CaP motoneuron CaP motoneuron axon branched , abnormal
CaP motoneuron axon truncated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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