ENSDARG00000025899


Danio rerio

Features
Gene ID: ENSDARG00000025899
  
Biological name :pnx
  
Synonyms : F1R2J1 / pnx / posterior neuron-specific homeobox
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 2799285
Gene end: 2801857
  
Corresponding Affymetrix probe sets: Dr.20039.1.S1_at (Zebrafish Array)   NM_178302_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000034835
NCBI entrez gene - 352939     See in Manteia.
RefSeq - NM_178302
RefSeq Peptide - NP_840087
swissprot - F1R2J1
ZFIN ID - ZDB-GENE-030328-42
Ensembl - ENSDARG00000025899
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nkx1.2lb / NK1 transcription factor related 2-like,b / Q15270* / NKX1-1* / NK1 homeobox 1* / NK1 transcription factor-related protein 1 *ENSDARG0000009942733
nkx1.2la / NK1 transcription factor related 2-like,a / Q9UD57* / NKX1-2* / P42580* / NK1 homeobox 2* / NK1 transcription factor-related protein 2 *ENSDARG0000000635031
gbx1 / gastrulation brain homeobox 1 / P82976* / Q14549* / Homeobox protein GBX-1 *ENSDARG0000007141827
gbx2 / gastrulation brain homeobox 2 / P48031* / P52951* / Homeobox protein GBX-2 *ENSDARG0000000293326
mnx2b / motor neuron and pancreas homeobox 2bENSDARG0000003035024
mnx1 / motor neuron and pancreas homeobox 1 / P50219* / Q9QZW9*ENSDARG0000003598424
mnx2a / motor neuron and pancreas homeobox 2aENSDARG0000004210623
vox / ventral homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000009976123
vent / ventral expressed homeobox / VENTX* / O95231* / VENT homeobox*ENSDARG0000010048321
meox1 / F1Q4R9 / mesenchyme homeobox 1ENSDARG0000000789120
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000010008720
evx1 / even-skipped homeobox 1 / P23683* / P49640* / Homeobox even-skipped homolog protein 1 *ENSDARG0000009936520
meox2b / mesenchyme homeobox 2b / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000006181819
ved / ventrally expressed dharma/bozozok antagonistENSDARG0000010238919
meox2a / mesenchyme homeobox 2a / MEOX2* / P50222* / P32443* / mesenchyme homeobox 2* / Homeobox protein MOX-2 *ENSDARG0000004091119
evx2 / even-skipped homeobox 2ENSDARG0000005925519
eve1 / even-skipped-like1ENSDARG0000005601218


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site
 IPR020479  Homeobox domain, metazoa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0050767 regulation of neurogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron decreased amount , abnormal
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 ZFA:0009244 primary motor neuron primary motor neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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