ENSDARG00000016404


Danio rerio

Features
Gene ID: ENSDARG00000016404
  
Biological name :ptch1
  
Synonyms : patched 1 / ptch1
  
Possible biological names infered from orthology : Mus musculus patched 1 (Ptch1), transcript variant 2, mRNA. / Q13635 / Q61115
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 29962635
Gene end: 30068277
  
Corresponding Affymetrix probe sets: Dr.8054.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114906
Ensembl peptide - ENSDARP00000025418
NCBI entrez gene - 30189     See in Manteia.
RefSeq - NM_001305542
RefSeq Peptide - NP_001292471
swissprot - F1R8E2
swissprot - F1QHX5
ZFIN ID - ZDB-GENE-980526-196
Ensembl - ENSDARG00000016404
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTCH1ENSGALG00000012620Gallus gallus
 PTCH1ENSG00000185920Homo sapiens
 Ptch1ENSMUSG00000021466Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptch2 / patched 2 / 2 * / O35595* / Q9Y6C5*ENSDARG0000005502654
npc1 / Niemann-Pick disease, type C1 / O15118* / O35604* / Niemann-Pick C1 protein * / NPC intracellular cholesterol transporter 1*ENSDARG0000001718016
si:ch211-250m6.7 / PTCHD3* / Q0EEE2* / Q3KNS1* / patched domain containing 3*ENSDARG0000006887412
NPC1L1 / NPC1 like intracellular cholesterol transporter 1 / Q9UHC9*ENSDARG0000009955811
ptchd4 / Q5RIV7 / patched domain containing 4 / Q6ZW05* / Mus musculus patched domain containing 4 (Ptchd4), transcript variant 1, mRNA.*ENSDARG0000000824911
ptchd1 / patched domain containing 1 / Q14B62* / Q96NR3* / Patched domain-containing protein 1 *ENSDARG0000001806610
CR792422.1 / PTCHD3* / Q3KNS1* / patched domain containing 3*ENSDARG000000100758
ptch1 / patched 1 / Q13635* / Q61115* / Mus musculus patched 1 (Ptch1), transcript variant 2, mRNA.*ENSDARG000000958598


Protein motifs (from Interpro)
Interpro ID Name
 IPR000731  Sterol-sensing domain
 IPR003392  Protein patched/dispatched
 IPR004766  Transmembrane receptor, patched


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IMP
 biological_processGO:0001957 intramembranous ossification IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010002 cardioblast differentiation IGI
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IMP
 biological_processGO:0048635 negative regulation of muscle organ development IGI
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060042 retina morphogenesis in camera-type eye IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008158 hedgehog receptor activity IEA


Pathways (from Reactome)
Pathway description
Hedgehog off state
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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