ENSDARG00000017821


Danio rerio

Features
Gene ID: ENSDARG00000017821
  
Biological name :gata5
  
Synonyms : gata5 / GATA binding protein 5
  
Possible biological names infered from orthology : P97489 / Q9BWX5 / Transcription factor GATA-5
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 7379728
Gene end: 7391028
  
Corresponding Affymetrix probe sets: Dr.8100.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000026381
NCBI entrez gene - 30482     See in Manteia.
RefSeq - NM_131235
RefSeq Peptide - NP_571310
swissprot - Q9W6U0
ZFIN ID - ZDB-GENE-980526-340
Ensembl - ENSDARG00000017821
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GATA5ENSGALG00000005352Gallus gallus
 GATA5ENSG00000130700Homo sapiens
 Gata5ENSMUSG00000015627Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gata6 / GATA binding protein 6 / Q61169* / Q92908* / Transcription factor GATA-6 *ENSDARG0000010358946
gata4 / GATA binding protein 4 / P43694* / Q08369* / Transcription factor GATA-4 *ENSDARG0000009895244
gata3 / Q91428 / GATA binding protein 3 / P23771* / P23772* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*ENSDARG0000001652634
gata2a / GATA binding protein 2a / GATA2* / O09100* / P23769* / GATA binding protein 2* / Mus musculus GATA binding protein 2 (Gata2), transcript variant 2, mRNA.*ENSDARG0000005932733
gata1a / GATA binding protein 1a / GATA1* / P17679* / P15976* / GATA binding protein 1* / Erythroid transcription factor *ENSDARG0000001347732
gata2b / GATA binding protein 2bENSDARG0000000909431
gata1b / GATA binding protein 1b / GATA1* / P17679* / P15976* / GATA binding protein 1* / Erythroid transcription factor *ENSDARG0000005913028
trps1 / trichorhinophalangeal syndrome I / Q9UHF7* / transcriptional repressor GATA binding 1*ENSDARG0000010408223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000679  Zinc finger, GATA-type
 IPR008013  GATA-type transcription activator, N-terminal
 IPR013088  Zinc finger, NHR/GATA-type
 IPR016375  Transcription factor GATA-4/5/6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001706 endoderm formation IMP
 biological_processGO:0001889 liver development IMP
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007492 endoderm development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0030099 myeloid cell differentiation IGI
 biological_processGO:0030878 thyroid gland development IMP
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0048618 post-embryonic foregut morphogenesis IMP
 biological_processGO:0055007 cardiac muscle cell differentiation IMP
 biological_processGO:0060972 left/right pattern formation IMP
 biological_processGO:0060975 cardioblast migration to the midline involved in heart field formation IGI
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000990 transcription factor activity, core RNA polymerase binding IDA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000028 heart primordium heart primordium left side unfused from heart primordium right side, abnormal
Show

 ZFA:0000056 pharynx pharynx increased amount , abnormal
pharynx increased width , abnormal
Show

 ZFA:0000114 heart heart physical object quality , abnormal
heart bifurcated , abnormal
heart quality , abnormal
heart position , abnormal
heart increased amount , abnormal
heart decreased size , abnormal
heart cardiac muscle cell decreased amount , abnormal
heart duplicated , abnormal
heart morphology , abnormal
heart spatial pattern , abnormal
heart increased distribution , abnormal
Show

 ZFA:0000360 heart tube heart tube fused with heart tube , abnormal
heart tube duplicated , abnormal
heart tube malformed , abnormal
heart tube bifurcated , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
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 ZFA:0001174 pharyngeal epithelium pharyngeal epithelium absent , abnormal
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 ZFA:0001338 intestine intestine decreased size , abnormal
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 ZFA:0001383 fin bud fin bud aplastic , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0005041 anterior lateral plate mesoderm anterior lateral plate mesoderm myocardial precursor decreased amount , abnormal
anterior lateral plate mesoderm decreased amount , abnormal
anterior lateral plate mesoderm physical object quality , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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