| MP:0000231 | hypertension | "sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0000274 | enlarged heart | "increase over normal size of the heart" [J:29971] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0000280 | thin ventricular wall | "decreased depth of the cardiac wall of the heart ventricles" [J:45302] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0000301 | reduced size of endocardial cushions | "smaller than normal mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29973] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0000516 | abnormal urinary system morphology | "structural or developmental anomaly of any of the organs involved in the production or excretion of urine " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Trpm5tm1Dgen/Trpm5tm1Dgen
Genetic Background: B6.129P2-Trpm5tm1Dgen
|
| MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
Allelic Composition: Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001139 | abnormal vagina morphology | "malformation of the female reproductive canal located between the uterus and the vulva" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0001140 | abnormal vaginal epithelium | "malformation of the epithelial layer of the vagina" [J:54637, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0001142 | abnormal vaginal opening | "a malformed or absent opening to the genital canal" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0001613 | abnormal vasodilation | "anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0001785 | edema | "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001859 | kidney inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0001914 | hemorrhage | "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
Show
Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0002128 | abnormal blood circulation | "failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0002652 | thin myocardial wall | "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0002962 | increased protein excretion | "greater than the normal amount of serum proteins voided by the kidneys" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0003315 | abnormal perineum morphology | "malformation in the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0003316 | perineal fistula | "an abnormal anatomical passage that connects the perineum to organs such as the bladder or the rectum " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0003529 | enlarged clitoris | "increased size of the small, erectile body located at the anterior end of the vulva" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0003541 | vaginal inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the vagina" [ncbi:Matthew Mailman, NCBI request] |
Show
Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
|
| MP:0003550 | short perineum | "reduced length of the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
Allelic Composition: Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0003567 | abnormal cardiomyocyte proliferation | "anomalous division or replication of cardiac muscle cells" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0003915 | increased left ventricle weight | "greater than average weight of the left ventricle compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0003920 | abnormal right ventricle morphology | "structural anomaly of the right lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0004067 | abnormal ventricular trabeculae morphology | "aberrant structure of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0004217 | salt-sensitive hypertension | "sustained high blood pressure that is maintained with a normal or increase in the amount of salt consumed in the diet; blood pressure may return to normotensive with a low salt diet" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0004564 | enlarged myocardial fiber | "increased size of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0004567 | decreased myocardial fiber number | "decreased number of cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0005264 | glomerulosclerosis | "hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0005325 | abnormal glomerulus | "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
|
| MP:0005528 | decreased glomerular filtration rate | "less than the normal volume of water filtered out of the plasma through glomerular capillary walls into thte Bowman s capsule per unit time" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
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| MP:0005583 | decreased renin activity | "less than the normal ability of this enzyme to cleave angiotensinogen and create angiotensin I" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
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| MP:0005600 | increased ventricle muscle contractility | "greater thant the normal ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0006138 | congestive heart failure | "the heart is unable to adequately pump blood throughout the body" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0006143 | increased diastolic blood pressure | "abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
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| MP:0006144 | increased systolic blood pressure | "abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
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| MP:0008727 | enlarged right atrium | "increased size of the right upper chamber of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0008788 | abnormal fetal cardiomyocyte morphology | "any structural anomaly of fetal and neonatal heart cells that undergo proliferation and are not yet terminally differentiated into binucleate or multinucleate cardiac myocytes" [PMID:17429040] |
Show
Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
|
| MP:0010404 | ostium primum atrial septal defect | "interatrial communication (atrial septal defect) through the most anterior and inferior aspect of the atrial septum" [http://emedicine.medscape.com, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010408 | sinus venosus atrial septal defect | "interatrial communication (atrial septal defect) through the upper atrial septum and that is contiguous with the superior vena cava (SVC); it is rostral and posterior to the fossa ovalis (where secundum type defects occur) and is separate from it" [http://emedicine.medscape.com, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
| MP:0010413 | complete atrioventricular septal defect | "a type of atrioventricular septal defect in which a single atrioventricular valve annulus, a common atrioventricular valve, and a defect of the inlet ventricular septum are observed; deficiency of the atrioventricular septum also results in the presence of a large primum atrial septal defect" [http://emedicine.medscape.com] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010419 | inlet ventricular septal defect | "abnormal communications between the two lower chambers of the heart, located posterior to the septal leaflet of the tricuspid valve and which are not associated with defects of the atrioventricular valves" [http://emedicine.medscape.com] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010428 | abnormal heart right ventricle outflow tract morphology | "any structural anomaly of the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010429 | abnormal heart left ventricle outflow tract morphology | "any structural anomaly of the anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010463 | aorta stenosis | "diffuse constriction or narrowing of the aorta" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
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| MP:0010484 | bicuspid aortic valve | "the presence of two cusps in the aortic valve instead of three" [http://emedicine.medscape.com] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
Allelic Composition: Gata5tm1.1Nemr/Gata5tm1.1Nemr,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129 * C57BL/6 * SJL
|
| MP:0010503 | myocardial trabeculae hypoplasia | "underdevelopment or reduced size of the supporting bundles of muscular fibers lining the walls of the heart, usually due to a reduced number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
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| MP:0010556 | thin ventricle myocardium compact layer | "reduced thickness of the ventricular portion of the outer, dense layer of the myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010587 | conotruncal ridge hypoplasia | "underdevelopment or reduced size of the pair of spiral mesenchymal swellings in the primordial ventricular outflow tract, that eventually fuse to form the conotruncal septum, dividing the subvalvular outflow tract and contributing to the membranous interventricular septum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:8823298] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010595 | abnormal aortic valve cusp morphology | "any structural anomaly of the three fibrous triangular components and associated flap of the aortic valve" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
Allelic Composition: Gata5tm1.1Nemr/Gata5tm1.1Nemr,Tg(Tek-cre)1Ywa/0
Genetic Background: involves: 129 * C57BL/6 * SJL
|
| MP:0010640 | ventricular myocardium compact layer hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the ventricular portion of the outer, dense layer of the myocardium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0010724 | thick interventricular septum | "increased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
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| MP:0011099 | complete lethality throughout fetal growth and development | "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Gata4tm1Jml/Gata4+,Gata5tm1Eem/Gata5tm1Eem
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0011485 | abnormal urethra urothelium morphology | "any structural anomaly of the epithelial lining of the luminal space of the urethra" [MGI:csmith] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
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| MP:0011572 | abnormal aorta bulb morphology | "any structural anomaly of the portion of the left ventricular outflow tract delineated by the sinotubular ridge superiorly and the bases of the valve leaflets inferiorly; it comprises the aortic sinuses, the aortic valve leaflets, the commissures, and the interleaflet triangles" [MGI:csmith, PMID:10722531] |
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Allelic Composition: Pnpla2tm1.1Hsul/Pnpla2tm1.1Hsul,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
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| MP:0011749 | perivascular fibrosis | "invasion of fibrous connective tissue into the perivascular tissue, often resulting from inflammation or injury" [MGI:csmith] |
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Allelic Composition: Senp1tm1Wami/Senp1tm1Wami,Tg(Adipoq-cre)1Evdr/0
Genetic Background: B6.Cg-Senp1tm1Wami Tg(Adipoq-cre)1Evdr
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| MP:0011763 | urethritis | "local accumulation of fluid, plasma proteins, and leukocytes in the urethra, usually caused by an infection" [MGI:anna] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
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| MP:0011780 | abnormal female urethra morphology | "any structural anomaly of the short and relatively simple female fibromuscular tubular canal which extends from the urinary bladder outlet to the perineum adjacent to the anterior wall of the vagina, and opens in the vestibule of the vagina posterior to the clitoris and anterior to the vaginal orifice; small mucus urethral glands (Skene s glands) open along its entire length and drain into a single paraurethral duct, which empties at the lateral margin of the external urethral orifice: its epithelial lining changes from transitional epithelium at the bladder end to non-keratinizing stratified squamous epithelium distally" [MGI:anna] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
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| MP:0011850 | absent clitoral bone | "absence of the unique bone located in the clitoris of most mammals except humans" [MGI:anna] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
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| MP:0013313 | female preputial gland hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of any of the paired, lobulated, modified sebaceous glands located on the side of the clitoris in female rodents" [MGI:Anna] |
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Allelic Composition: Myctm2Dmlo/Myctm2Dmlo
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6J * MF1
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