ENSMUSG00000038679


Mus musculus

Features
Gene ID: ENSMUSG00000038679
  
Biological name :Trps1
  
Synonyms : transcriptional repressor GATA binding 1 / Trps1
  
Possible biological names infered from orthology : Q9UHF7
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: C
Gene start: 50654752
Gene end: 50890463
  
Corresponding Affymetrix probe sets: 10428534 (MoGene1.0st)   10428536 (MoGene1.0st)   1434286_at (Mouse Genome 430 2.0 Array)   1438214_at (Mouse Genome 430 2.0 Array)   1449530_at (Mouse Genome 430 2.0 Array)   1457445_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139115
Ensembl peptide - ENSMUSP00000077089
Ensembl peptide - ENSMUSP00000129779
Ensembl peptide - ENSMUSP00000138835
Ensembl peptide - ENSMUSP00000138905
Ensembl peptide - ENSMUSP00000138967
Ensembl peptide - ENSMUSP00000139017
Ensembl peptide - ENSMUSP00000139063
NCBI entrez gene - 83925     See in Manteia.
MGI - MGI:1927616
RefSeq - XM_011245780
RefSeq - NM_001310481
RefSeq - NM_001310485
RefSeq - NM_032000
RefSeq - XM_006521560
RefSeq - XM_006521563
RefSeq - XM_011245776
RefSeq - XM_011245777
RefSeq - XM_011245778
RefSeq Peptide - NP_114389
RefSeq Peptide - NP_001297410
RefSeq Peptide - NP_001297414
swissprot - V9GXE9
swissprot - G3UW90
swissprot - Q80V18
swissprot - V9GX39
swissprot - Q8BZ62
swissprot - V9GX74
swissprot - V9GXA5
Ensembl - ENSMUSG00000038679
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trps1ENSDARG00000104082Danio rerio
 TRPS1ENSGALG00000031700Gallus gallus
 TRPS1ENSG00000104447Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gata3 / P23772 / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA. / P23771* / GATA binding protein 3*ENSMUSG000000156199
Gata6 / Q61169 / Transcription factor GATA-6 / Q92908* / GATA binding protein 6*ENSMUSG000000058369
Gata5 / P97489 / Transcription factor GATA-5 / Q9BWX5* / GATA binding protein 5*ENSMUSG000000156278
Gata4 / Q08369 / Transcription factor GATA-4 / P43694* / GATA binding protein 4*ENSMUSG000000219448
Gata2 / O09100 / Mus musculus GATA binding protein 2 (Gata2), transcript variant 2, mRNA. / P23769* / GATA binding protein 2*ENSMUSG000000150538
Gata1 / P17679 / Erythroid transcription factor / P15976* / GATA binding protein 1*ENSMUSG000000311627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000679  Zinc finger, GATA-type
 IPR013087  Zinc finger C2H2-type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR028440  Transcription factor TRPS1
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
Show

Allelic Composition: Trps1tm1.1Shiv/Trps1+
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)

 MP:0000069 kyphoscoliosis "kyphosis combined with scoliosis" [MGI:CML, J:66943]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0000097 short maxilla "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000161 scoliosis "lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000166 abnormal chondrocyte morphology "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0000377 abnormal hair follicle "malformed invagination of the epidermis from which the hair shaft develops" [J:65031]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0000379 reduced hair follicle number "fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Trps1tm1.1Shiv/Trps1+
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0000416 sparse fur "fur that is significantly less dense" [J:46854]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0000527 abnormal kidney development "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001175 abnormal lung morphology "malformed organ of respiration" [J:35802]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0001177 atelectasis "collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001179 thicker alveolar septa 
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001216 abnormal epidermal layer morphology "anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: H2dlAb1-Ea/H2dlAb1-Ea,Rag1tm1Mom/Rag1tm1Mom,Tg(HLA-DRA,HLA-DRB5*0101)loKito/0,Tg(TRATL3A6,TRBTL3A6)#Kito/0
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6

 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002270 abnormal alveoli morphology "any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002273 abnormal alveolar epithelial cell morphology "any structural anomaly of the cells lining the alveoli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002282 abnormal trachea morphology "structral anomaly of the tube descending from the larynx and branching into the right and left main bronchi" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0002427 dwarfism "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Raratm3Ipc/Rara+,Speer6-ps1Tg(Alb-cre)21Mgn/?,Trim24tm1Los/Trim24tm1Los
Genetic Background: involves: 129/Sv * C57BL/6 * DBA * SJL

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003641 small lung "reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0003704 abnormal hair follicle development "anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003761 arched palate "abnormally concaved shape to the roof of the oral cavity" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Trps1tm1.1Shiv/Trps1+
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)

 MP:0004320 split sternum "the appearance of an abnormal division in the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004321 short sternum "reduced length of the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004505 decreased renal glomerulus number "reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004553 absent tracheal cartilage rings "absence of the 16-20 incomplete rings of hyaline cartilage forming the skeleton of the trachea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004624 abnormal thoracic cage "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004674 thin ribs "a more slender appearance of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008271 abnormal bone ossification "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010099 abnormal thoracic cage shape "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010103 small thoracic cage "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010981 abnormal branching involved in ureteric bud morphogenesis "anomaly in the process in which the branching structure of the ureteric bud is generated and organized" [GO:0001658]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010984 abnormal metanephric mesenchyme morphology "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Cdk2tm1Sgo/Cdk2tm1Sgo,Cdk4tm1Bbd/Cdk4tm1Bbd,Cdk6tm1Bbd/Cdk6tm1Bbd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Trps1tm1Shiv/Trps1tm1Shiv
Genetic Background: either: (involves: 129S4/SvJae) or (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)

Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011290 decreased nephron number "reduction in the total number of filtering units of the kidney" [MGI:anna]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011425 abnormal kidney interstitium morphology "any structural anomaly of the kidney region located between the nephrons, ureteric epithelia (ureteric tips, trunk and collecting duct system) and renal vasculature, and composed of renal support cells, including fibroblasts and macrophages, and mesenchymal stroma or interstitial cells; the renal vasculature lies within the renal interstitium but is not a part of it; various conditions can lead to scarring (fibrosis) and congestion of this area, which can cause kidney dysfunction and failure" [MGI:anna]
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Allelic Composition: Trps1tm1Ymur/Trps1tm1Ymur
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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