ENSDARG00000019516


Danio rerio

Features
Gene ID: ENSDARG00000019516
  
Biological name :sp7
  
Synonyms : sp7 / Sp7 transcription factor
  
Possible biological names infered from orthology : Mus musculus Sp7 transcription factor 7 (Sp7), transcript variant 2, mRNA. / Q8TDD2 / Q8VI67
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 58622831
Gene end: 58674160
  
Corresponding Affymetrix probe sets: DrAffx.2.10.S1_s_at (Zebrafish Array)   NM_212863_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000110025
NCBI entrez gene - 405789     See in Manteia.
RefSeq - NM_212863
RefSeq Peptide - NP_998028
swissprot - F6P1R7
ZFIN ID - ZDB-GENE-040629-2
Ensembl - ENSDARG00000019516
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SP7ENSG00000170374Homo sapiens
 Sp7ENSMUSG00000060284Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sp9 / Q6NW96 / sp9 transcription factor / Q64HY3* / P0CG40* / Transcription factor Sp9 *ENSDARG0000009937430
sp8a / sp8 transcription factor a / SP8* / Q8IXZ3* / Q8BMJ8* / Sp8 transcription factor* / Transcription factor Sp8 *ENSDARG0000001187029
sp8b / Q6P0J3 / sp8 transcription factor bENSDARG0000005666629
sp4 / sp4 transcription factor / Q02446*ENSDARG0000000518624
sp3a / sp3a transcription factor / SP3* / Q02447* / O70494* / Sp3 transcription factor* / Transcription factor Sp3 *ENSDARG0000000154923
sp3b / Sp3b transcription factor / SP3* / Q02447* / O70494* / Sp3 transcription factor* / Transcription factor Sp3 *ENSDARG0000000781222
sp1 / sp1 transcription factor / O89090* / P08047* / Transcription factor Sp1 *ENSDARG0000008834722
sp5a / Sp5 transcription factor a / SP5* / Q9JHX2* / Q6BEB4* / Sp5 transcription factor* / Transcription factor Sp5 *ENSDARG0000007657121
sp5l / Sp5 transcription factor-like / SP5* / Q6BEB4* / Sp5 transcription factor*ENSDARG0000011586819
FO704755.1ENSDARG0000000584619
sp2 / sp2 transcription factor / Q02086*ENSDARG0000007676319
sp6 / Sp6 transcription factor / Q3SY56* / Q9ESX2* / trans-acting transcription factor 6*ENSDARG0000009988017
klf11b / Kruppel-like factor 11b / KLF11* / Q8K1S5* / O14901* / Kruppel like factor 11* / Krueppel-like factor 11 *ENSDARG0000001379416
klf11a / Kruppel-like factor 11a / KLF11* / Q8K1S5* / O14901* / Kruppel like factor 11* / Krueppel-like factor 11 *ENSDARG0000003084415
klf13 / Kruppel-like factor 13 / Q9JJZ6* / Q9Y2Y9* / Krueppel-like factor 13 *ENSDARG0000006136813
zgc:153115ENSDARG0000006934212
klf9 / Kruppel-like factor 9 / Q13886*ENSDARG0000006819411


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IMP
 biological_processGO:0033688 regulation of osteoblast proliferation IMP
 biological_processGO:0060363 cranial suture morphogenesis IMP
 molecular_functionGO:0003676 nucleic acid binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000184 cleithrum cleithrum decreased size , abnormal
cleithrum decreased distribution , abnormal
Show

 ZFA:0000250 opercle opercle decreased size , abnormal
opercle poorly ossified , abnormal
Show

 ZFA:0000253 orbitosphenoid orbitosphenoid poorly ossified , abnormal
Show

 ZFA:0000419 pterosphenoid pterosphenoid poorly ossified , abnormal
Show

 ZFA:0000434 skeletal system skeletal system bone mineralization decreased process quality , abnormal
Show

 ZFA:0000486 parietal bone parietal bone apatite decreased amount , abnormal
parietal bone osteoblast morphology , abnormal
Show

 ZFA:0000514 frontal bone frontal bone decreased thickness , abnormal
Show

 ZFA:0000538 rib rib broken , abnormal
Show

 ZFA:0000561 parasphenoid parasphenoid bent , abnormal
parasphenoid deformed , abnormal
parasphenoid increased angle to frontal bone , abnormal
Show

 ZFA:0000737 cranium cranium bone mineralization decreased process quality , abnormal
cranium fibrous joint increased amount , abnormal
cranium domed , abnormal
cranium has extra parts of type bone element , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001189 vertebra vertebra morphology , abnormal
vertebra shape , abnormal
vertebra size , abnormal
Show

 ZFA:0001272 palatoquadrate arch palatoquadrate arch truncated , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch protruding , abnormal
Show

 ZFA:0001502 epiphyseal bar epiphyseal bar increased width , abnormal
Show

 ZFA:0001550 caudal fin lepidotrichium caudal fin lepidotrichium undulate , abnormal
Show

 ZFA:0001559 vertebral column vertebral column increased curvature , abnormal
vertebral column bone mineralization variability , abnormal
vertebral column bone mineralization decreased process quality , abnormal
Show

 ZFA:0005476 inter-ventral hypohyal joint inter-ventral hypohyal joint increased width , abnormal
Show

 ZFA:0005606 cranial vault cranial vault fibrous joint morphology , abnormal
cranial vault anterior region truncated , abnormal
cranial vault morphology , abnormal
cranial vault closure incomplete , abnormal
cranial vault bone element irregularly shaped , abnormal
Show

 ZFA:0005851 ceratobranchial 5 primary tooth ceratobranchial 5 primary tooth tooth mineralization decreased process quality , abnormal
Show

 ZFA:0009031 osteoblast osteoblast nucleus composition , abnormal
osteoblast nucleus circular , abnormal
osteoblast extracellular matrix composition , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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