ENSDARG00000025372


Danio rerio

Features
Gene ID: ENSDARG00000025372
  
Biological name :admp
  
Synonyms : admp / anti-dorsalizing morphogenic protein
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 53483322
Gene end: 53500424
  
Corresponding Affymetrix probe sets: Dr.6988.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000037833
swissprot - F1R5Z7
ZFIN ID - ZDB-GENE-011214-1
Ensembl - ENSDARG00000025372
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ADMPENSGALG00000037408Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bmp7a / bone morphogenetic protein 7a / BMP7* / P23359* / P18075* / Bone morphotic protein 7 * / bone morphogenetic protein 7*ENSDARG0000001826031
bmp4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *ENSDARG0000001999530
bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000004143030
bmp2a / bone morphogenetic protein 2a / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000001340929
bmp6 / bone morphogenetic protein 6 / P20722* / P22004* / Bone morphotic protein 6 *ENSDARG0000001568629
bmp5 / bone morphogenetic protein 5 / P22003*ENSDARG0000010170129
bmp7b / bone morphogenetic protein 7bENSDARG0000006323029
gdf6b / A8E7N9 / growth differentiation factor 6b / GDF6* / Q6KF10* / P43028* / growth differentiation factor 6*ENSDARG0000000551027
bmp16 / bone morphogenetic protein 16ENSDARG0000010367927
gdf6a / P85857 / growth differentiation factor 6a / GDF6* / P43028* / Q6KF10* / growth differentiation factor 6*ENSDARG0000005347926
gdf7 / growth differentiation factor 7 / P43029* / Q7Z4P5*ENSDARG0000004278426
bmp8a / bone morphogenetic protein 8a / BMP8B* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8B * / Bone morphotic protein 8A * / bone morphogenetic protein 8b*ENSDARG0000003567726
bmp10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *ENSDARG0000006176925
gdf5 / growth differentiation factor 5 / P43026* / P43027*ENSDARG0000000276025
bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*ENSDARG0000010923323
gdf2 / F1QWZ4 / growth differentiation factor 2 / Q9UK05* / Q9WV56*ENSDARG0000005917323


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048264 determination of ventral identity IMP
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060063 Spemann organizer formation at the embryonic shield IMP
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000071 shield shield increased size , abnormal
Show

 ZFA:0000132 neural plate neural plate increased size , abnormal
Show

 ZFA:0000135 notochord notochord increased width , abnormal
notochord increased size , abnormal
notochord has extra parts of type notochord cell, abnormal
Show

 ZFA:0001094 whole organism whole organism wholly dorsalized , abnormal
whole organism morphology , abnormal
whole organism lacks parts or has fewer parts of type post-vent region , abnormal
whole organism decreased length , abnormal
whole organism lacks all parts of type extension , abnormal
Show

 ZFA:0001115 trunk trunk morphology , abnormal
trunk decreased size , abnormal
trunk increased size , abnormal
Show

 ZFA:0001670 notochord posterior region notochord posterior region bifurcated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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