Manteia

ENSDARG00000015686

Danio rerio

Features

Gene ID:	ENSDARG00000015686

Biological name :	bmp6

Synonyms :	bmp6 / bone morphogenetic protein 6

Possible biological names infered from orthology :	Bone morphotic protein 6 / P20722 / P22004

Species:	Danio rerio

Chr. number:	24
Strand:	1
Band:
Gene start:	7861373
Gene end:	7935809

Corresponding Affymetrix probe sets:	Dr.15495.1.A1_at (Zebrafish Array) NM_001013339_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000022649 Ensembl peptide - ENSDARP00000112872 NCBI entrez gene - 503761 See in Manteia. RefSeq - NM_001013339 RefSeq Peptide - NP_001013357 swissprot - F1R678 swissprot - E9QDT7 ZFIN ID - ZDB-GENE-050306-42 Ensembl - ENSDARG00000015686

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
BMP6	ENSGALG00000012787	Gallus gallus
BMP6	ENSG00000153162	Homo sapiens
Bmp6	ENSMUSG00000039004	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
bmp7b / bone morphogenetic protein 7b	ENSDARG00000063230	63
bmp5 / bone morphogenetic protein 5 / P22003*	ENSDARG00000101701	60
bmp7a / bone morphogenetic protein 7a / BMP7* / P23359* / P18075* / Bone morphotic protein 7 * / bone morphogenetic protein 7*	ENSDARG00000018260	55
bmp8a / bone morphogenetic protein 8a / BMP8B* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8B * / Bone morphotic protein 8A * / bone morphogenetic protein 8b*	ENSDARG00000035677	44
bmp4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *	ENSDARG00000019995	30
bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*	ENSDARG00000041430	29
bmp2a / bone morphogenetic protein 2a / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*	ENSDARG00000013409	28
admp / anti-dorsalizing morphogenic protein	ENSDARG00000025372	27
bmp16 / bone morphogenetic protein 16	ENSDARG00000103679	26
gdf5 / growth differentiation factor 5 / P43026* / P43027*	ENSDARG00000002760	24
bmp10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *	ENSDARG00000061769	24
gdf7 / growth differentiation factor 7 / P43029* / Q7Z4P5*	ENSDARG00000042784	23
gdf6b / A8E7N9 / growth differentiation factor 6b / GDF6* / Q6KF10* / P43028* / growth differentiation factor 6*	ENSDARG00000005510	23
bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*	ENSDARG00000109233	23
gdf2 / F1QWZ4 / growth differentiation factor 2 / Q9UK05* / Q9WV56*	ENSDARG00000059173	22
gdf6a / P85857 / growth differentiation factor 6a / GDF6* / P43028* / Q6KF10* / growth differentiation factor 6*	ENSDARG00000053479	22

Protein motifs (from Interpro)

Interpro ID	Name
IPR001111	TGF-beta, propeptide
IPR001839	Transforming growth factor-beta, C-terminal
IPR015615	Transforming growth factor-beta-related
IPR017948	Transforming growth factor beta, conserved site
IPR029034	Cystine-knot cytokine

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA
biological_process	GO:0030509	BMP signaling pathway	IBA
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0043408	regulation of MAPK cascade	IBA
biological_process	GO:0048468	cell development	IBA
biological_process	GO:0060395	SMAD protein signal transduction	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IBA
molecular_function	GO:0005125	cytokine activity	IBA
molecular_function	GO:0005160	transforming growth factor beta receptor binding	IBA
molecular_function	GO:0008083	growth factor activity	IEA
molecular_function	GO:0070700	BMP receptor binding	IBA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr