ENSDARG00000061769


Danio rerio

Features
Gene ID: ENSDARG00000061769
  
Biological name :bmp10
  
Synonyms : bmp10 / bone morphogenetic protein 10
  
Possible biological names infered from orthology : Bone morphotic protein 10 / O95393 / Q9R229
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 21211135
Gene end: 21214299
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000082925
NCBI entrez gene - 562533     See in Manteia.
RefSeq - NM_001130600
RefSeq Peptide - NP_001124072
swissprot - A2BGK2
ZFIN ID - ZDB-GENE-060526-211
Ensembl - ENSDARG00000061769
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BMP10ENSGALG00000000120Gallus gallus
 BMP10ENSG00000163217Homo sapiens
 Bmp10ENSMUSG00000030046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*ENSDARG0000010923338
gdf2 / F1QWZ4 / growth differentiation factor 2 / Q9UK05* / Q9WV56*ENSDARG0000005917330
bmp2a / bone morphogenetic protein 2a / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000001340924
bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*ENSDARG0000004143024
bmp5 / bone morphogenetic protein 5 / P22003*ENSDARG0000010170122
bmp16 / bone morphogenetic protein 16ENSDARG0000010367922
bmp4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *ENSDARG0000001999522
bmp7b / bone morphogenetic protein 7bENSDARG0000006323022
bmp7a / bone morphogenetic protein 7a / BMP7* / P23359* / P18075* / Bone morphotic protein 7 * / bone morphogenetic protein 7*ENSDARG0000001826022
bmp6 / bone morphogenetic protein 6 / P20722* / P22004* / Bone morphotic protein 6 *ENSDARG0000001568621
bmp8a / bone morphogenetic protein 8a / BMP8B* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8B * / Bone morphotic protein 8A * / bone morphogenetic protein 8b*ENSDARG0000003567720
gdf6a / P85857 / growth differentiation factor 6a / GDF6* / P43028* / Q6KF10* / growth differentiation factor 6*ENSDARG0000005347920
gdf5 / growth differentiation factor 5 / P43026* / P43027*ENSDARG0000000276020
admp / anti-dorsalizing morphogenic proteinENSDARG0000002537220
gdf6b / A8E7N9 / growth differentiation factor 6b / GDF6* / Q6KF10* / P43028* / growth differentiation factor 6*ENSDARG0000000551019
gdf7 / growth differentiation factor 7 / P43029* / Q7Z4P5*ENSDARG0000004278418


Protein motifs (from Interpro)
Interpro ID Name
 IPR001111  TGF-beta, propeptide
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0030509 BMP signaling pathway IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 biological_processGO:0060840 artery development IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Signaling by BMP
Molecules associated with elastic fibres


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001051 caudal division of the internal carotid artery caudal division of the internal carotid artery increased size , abnormal
Show

 ZFA:0001267 cranial vasculature cranial vasculature malformed , abnormal
Show

 ZFA:0005000 basal communicating artery basal communicating artery increased size , abnormal
Show

 ZFA:0009065 endothelial cell endothelial cell increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018179 acvrl1 / activin A receptor like type 1 / P37023* / Q61288* / Serine/threonine-protein kinase receptor R3 *  / complex / reaction
 ENSDARG00000109233 bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*  / complex
 ENSDARG00000061769 bmp10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *  / complex






 

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