Manteia

ENSDARG00000013409

Danio rerio

Features

Gene ID:	ENSDARG00000013409

Biological name :	bmp2a

Synonyms :	bmp2a / bone morphogenetic protein 2a

Possible biological names infered from orthology :	BMP2 / bone morphogenetic protein 2 / Bone morphotic protein 2 / P12643 / P21274

Species:	Danio rerio

Chr. number:	17
Strand:	-1
Band:
Gene start:	4227254
Gene end:	4231532

Corresponding Affymetrix probe sets:	Dr.1463.1.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000013686 swissprot - B3DI86 ZFIN ID - ZDB-GENE-980526-388 Ensembl - ENSDARG00000013409

See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
BMP2	ENSGALG00000029301	Gallus gallus
BMP2	ENSG00000125845	Homo sapiens
Bmp2	ENSMUSG00000027358	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
bmp2b / bone morphogenetic protein 2b / BMP2* / P21274* / P12643* / Bone morphotic protein 2 * / bone morphogenetic protein 2*	ENSDARG00000041430	67
bmp4 / bone morphogenetic protein 4 / P12644* / P21275* / Bone morphotic protein 4 *	ENSDARG00000019995	57
bmp16 / bone morphogenetic protein 16	ENSDARG00000103679	43
bmp5 / bone morphogenetic protein 5 / P22003*	ENSDARG00000101701	31
bmp10 / bone morphogenetic protein 10 / O95393* / Q9R229* / Bone morphotic protein 10 *	ENSDARG00000061769	30
bmp8a / bone morphogenetic protein 8a / BMP8B* / Q7Z5Y6* / P34820* / P34821* / P55105* / Bone morphotic protein 8B * / Bone morphotic protein 8A * / bone morphogenetic protein 8b*	ENSDARG00000035677	30
gdf2 / F1QWZ4 / growth differentiation factor 2 / Q9UK05* / Q9WV56*	ENSDARG00000059173	30
bmp7b / bone morphogenetic protein 7b	ENSDARG00000063230	30
bmp6 / bone morphogenetic protein 6 / P20722* / P22004* / Bone morphotic protein 6 *	ENSDARG00000015686	30
admp / anti-dorsalizing morphogenic protein	ENSDARG00000025372	30
bmp7a / bone morphogenetic protein 7a / BMP7* / P23359* / P18075* / Bone morphotic protein 7 * / bone morphogenetic protein 7*	ENSDARG00000018260	29
gdf6a / P85857 / growth differentiation factor 6a / GDF6* / P43028* / Q6KF10* / growth differentiation factor 6*	ENSDARG00000053479	28
gdf6b / A8E7N9 / growth differentiation factor 6b / GDF6* / Q6KF10* / P43028* / growth differentiation factor 6*	ENSDARG00000005510	27
gdf5 / growth differentiation factor 5 / P43026* / P43027*	ENSDARG00000002760	27
bmp10l / bone morphogenetic protein 10, like / BMP10* / O95393* / bone morphogenetic protein 10*	ENSDARG00000109233	27
gdf7 / growth differentiation factor 7 / P43029* / Q7Z4P5*	ENSDARG00000042784	27

Protein motifs (from Interpro)

Interpro ID	Name
IPR001111	TGF-beta, propeptide
IPR001839	Transforming growth factor-beta, C-terminal
IPR015615	Transforming growth factor-beta-related
IPR017948	Transforming growth factor beta, conserved site
IPR029034	Cystine-knot cytokine

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0000122	negative regulation of transcription by RNA polymerase II	IBA
biological_process	GO:0010469	regulation of signaling receptor activity	IEA
biological_process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA
biological_process	GO:0030513	positive regulation of BMP signaling pathway	IDA
biological_process	GO:0042981	regulation of apoptotic process	IBA
biological_process	GO:0043408	regulation of MAPK cascade	IBA
biological_process	GO:0048468	cell development	IBA
biological_process	GO:0060395	SMAD protein signal transduction	IBA
cellular_component	GO:0005576	extracellular region	IEA
cellular_component	GO:0005615	extracellular space	IBA
molecular_function	GO:0005125	cytokine activity	IBA
molecular_function	GO:0005160	transforming growth factor beta receptor binding	IBA
molecular_function	GO:0008083	growth factor activity	IEA
molecular_function	GO:0070700	BMP receptor binding	IBA

Pathways (from Reactome)

Pathway description

Signaling by BMP

Molecules associated with elastic fibres

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000019	epiphysis	epiphysis has fewer parts of type photoreceptor cell , abnormal	Show
ZFA:0001369	anterior pancreatic bud	anterior pancreatic bud hypoplastic , abnormal anterior pancreatic bud aplastic , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr