ENSDARG00000042041


Danio rerio

Features
Gene ID: ENSDARG00000042041
  
Biological name :tal2
  
Synonyms : tal2 / T-cell acute lymphocytic leukemia 2
  
Possible biological names infered from orthology : Q16559 / Q62282 / TAL bHLH transcription factor 2
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 9348284
Gene end: 9349045
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124306
NCBI entrez gene - 394239     See in Manteia.
swissprot - F1QUD8
ZFIN ID - ZDB-GENE-040115-1
Ensembl - ENSDARG00000042041
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TAL2ENSGALG00000023114Gallus gallus
 TAL2ENSG00000186051Homo sapiens
 Tal2ENSMUSG00000028417Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tal1 / O93507 / T-cell acute lymphocytic leukemia 1 / P22091* / P17542* / TAL bHLH transcription factor 1, erythroid differentiation factor*ENSDARG0000001993054
CABZ01066694.1 / LYL1* / P12980* / P27792* / Protein lyl-1 * / LYL1, basic helix-loop-helix family member*ENSDARG0000011017848
twist1a / twist family bHLH transcription factor 1a / Q8WVJ9* / TWIST1* / TWIST2* / P26687* / Q15672* / twist family bHLH transcription factor 1* / twist family bHLH transcription factor 2*...ENSDARG0000003040234
scxb / scleraxis bHLH transcription factor b / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000001163534
twist1b / twist family bHLH transcription factor 1b / Q8WVJ9* / TWIST1* / TWIST2* / P26687* / Q15672* / twist family bHLH transcription factor 1* / twist family bHLH transcription factor 2*...ENSDARG0000007601033
scxa / scleraxis bHLH transcription factor a / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000003569533
twist3ENSDARG0000001964633
tcf15 / transcription factor 15ENSDARG0000006754432
si:ch211-246m6.4ENSDARG0000004285732
twist2 / Q15672* / Q8WVJ9* / TWIST1* / P26687* / twist family bHLH transcription factor 2* / twist family bHLH transcription factor 1* / twist basic helix-loop-helix transcription factor 1*...ENSDARG0000007826632
nhlh2 / nescient helix loop helix 2 / NHLH1* / Q02575* / Q64221* / Q02576* / Q02577* / nescient helix-loop-helix 1*ENSDARG0000002549530
hand2 / heart and neural crest derivatives expressed 2 / P61296* / Q61039* / Heart- and neural crest derivatives-expressed protein 2 *ENSDARG0000000830526


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007420 brain development IEP
 biological_processGO:0021514 ventral spinal cord interneuron differentiation IMP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000778 spinal cord interneuron spinal cord interneuron cellular quality , abnormal
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 ZFA:0001256 lateral floor plate lateral floor plate Kolmer-Agduhr neuron cellular quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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