ENSDARG00000025495


Danio rerio

Features
Gene ID: ENSDARG00000025495
  
Biological name :nhlh2
  
Synonyms : nescient helix loop helix 2 / nhlh2
  
Possible biological names infered from orthology : nescient helix-loop-helix 1 / NHLH1 / Q02575 / Q02576 / Q02577 / Q64221
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 32978302
Gene end: 32981660
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015418
NCBI entrez gene - 402968     See in Manteia.
RefSeq - NM_205669
RefSeq Peptide - NP_991232
swissprot - Q6P0A8
ZFIN ID - ZDB-GENE-040426-1809
Ensembl - ENSDARG00000025495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NHLH1ENSGALG00000025817Gallus gallus
 NHLH1ENSG00000171786Homo sapiens
 NHLH2ENSG00000177551Homo sapiens
 Nhlh1ENSMUSG00000051251Mus musculus
 Nhlh2ENSMUSG00000048540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tal1 / O93507 / T-cell acute lymphocytic leukemia 1 / P22091* / P17542* / TAL bHLH transcription factor 1, erythroid differentiation factor*ENSDARG0000001993038
twist3ENSDARG0000001964632
scxa / scleraxis bHLH transcription factor a / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000003569531
si:ch211-246m6.4ENSDARG0000004285730
twist1b / twist family bHLH transcription factor 1b / Q8WVJ9* / TWIST1* / TWIST2* / P26687* / Q15672* / twist family bHLH transcription factor 1* / twist family bHLH transcription factor 2*...ENSDARG0000007601030
tcf15 / transcription factor 15ENSDARG0000006754430
scxb / scleraxis bHLH transcription factor b / SCX* / Q7RTU7* / Q64124* / scleraxis* / scleraxis bHLH transcription factor*ENSDARG0000001163530
CABZ01066694.1 / LYL1* / P12980* / P27792* / Protein lyl-1 * / LYL1, basic helix-loop-helix family member*ENSDARG0000011017828
twist1a / twist family bHLH transcription factor 1a / Q8WVJ9* / TWIST1* / TWIST2* / P26687* / Q15672* / twist family bHLH transcription factor 1* / twist family bHLH transcription factor 2*...ENSDARG0000003040228
twist2 / Q15672* / Q8WVJ9* / TWIST1* / P26687* / twist family bHLH transcription factor 2* / twist family bHLH transcription factor 1* / twist basic helix-loop-helix transcription factor 1*...ENSDARG0000007826628
tal2 / T-cell acute lymphocytic leukemia 2 / Q16559* / Q62282* / TAL bHLH transcription factor 2*ENSDARG0000004204127
hand2 / heart and neural crest derivatives expressed 2 / P61296* / Q61039* / Heart- and neural crest derivatives-expressed protein 2 *ENSDARG0000000830525


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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