ENSDARG00000044016


Danio rerio

Features
Gene ID: ENSDARG00000044016
  
Biological name :myo6a
  
Synonyms : myo6a / myosin VIa
  
Possible biological names infered from orthology : MYO6 / myosin VI / Q9UM54
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 715739
Gene end: 777219
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000027227
Ensembl peptide - ENSDARP00000112958
Ensembl peptide - ENSDARP00000115756
Ensembl peptide - ENSDARP00000126697
NCBI entrez gene - 445473     See in Manteia.
RefSeq - NM_001004111
RefSeq - XM_009294502
RefSeq - XM_021468404
RefSeq Peptide - NP_001004111
swissprot - F1Q6Q6
swissprot - E9QCU8
swissprot - R4GDY7
ZFIN ID - ZDB-GENE-040819-2
Ensembl - ENSDARG00000044016
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYO6ENSGALG00000015898Gallus gallus
 MYO6ENSG00000196586Homo sapiens
 Myo6ENSMUSG00000033577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myo6b / myosin VIb / MYO6* / Q9UM54* / myosin VI*ENSDARG0000004214183
myo7ab / myosin VIIAb / MYO7A* / P97479* / Q13402* / myosin VIIA* / Unconventional myosin-VIIa *ENSDARG0000004463227
si:ch73-194h10.2 / MYO7B* / Q6PIF6* / Q99MZ6* / myosin VIIB* / Unconventional myosin-VIIb *ENSDARG0000004444126
myo5b / myosin VB / Q9ULV0* / AC090227.1*ENSDARG0000006200326
myo7aa / myosin VIIAa / MYO7A* / Q13402* / myosin VIIA*ENSDARG0000009987126
myo5aa / myosin VAa / MYO5A* / Q99104* / Q9Y4I1* / myosin VA* / Unconventional myosin-Va *ENSDARG0000006163526
myo10l1 / myosin X-like 1ENSDARG0000007472325
myo9aa / myosin IXAa / MYO9A* / B2RTY4* / myosin IXA*ENSDARG0000007672925
myo5ab / myosin VAb / MYO5A* / Q99104* / Q9Y4I1* / myosin VA* / Unconventional myosin-Va *ENSDARG0000002521825
myo7bb / myosin VIIBb / MYO7B* / Q6PIF6* / Q99MZ6* / myosin VIIB* / Unconventional myosin-VIIb *ENSDARG0000007720125
myo10 / myosin X / F8VQB6* / Q9HD67* / Mus musculus myosin X (Myo10), transcript variant 3, mRNA.*ENSDARG0000001700425
myo5c / myosin VC / Q9NQX4*ENSDARG0000010423524
MYO9B / si:zfos-588f8.1 / Q13459* / myosin IXB*ENSDARG0000007831324
myo9ab / myosin IXAb / MYO9A* / Q8C170* / B2RTY4* / myosin IXA* / Unconventional myosin-IXa *ENSDARG0000007384323
myo9b / myosin IXb / Q13459*ENSDARG0000007741023
mbd3b / si:dkey-110c1.10ENSDARG0000006181021
myo10l3 / myosin X-like 3ENSDARG000000741438


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR004009  Myosin, N-terminal, SH3-like
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032412  Myosin VI, cargo binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0035479 angioblast cell migration from lateral mesoderm to midline IMP
 biological_processGO:0048844 artery morphogenesis IMP
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
Gap junction degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta decreased diameter , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel blood vessel endothelial cell slender , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel malformed , abnormal
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 ZFA:0005295 axial blood vessel axial blood vessel malformed , abnormal
Show

 ZFA:0009258 angioblastic mesenchymal cell angioblastic mesenchymal cell mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr